AR115883A1 - PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ADDICTION TO PSYCHOACTIVE SUBSTANCES AND / OR FOR THE PREVENTION OF RELIPS TO SUCH ADDICTION - Google Patents

PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ADDICTION TO PSYCHOACTIVE SUBSTANCES AND / OR FOR THE PREVENTION OF RELIPS TO SUCH ADDICTION

Info

Publication number
AR115883A1
AR115883A1 ARP190102178A ARP190102178A AR115883A1 AR 115883 A1 AR115883 A1 AR 115883A1 AR P190102178 A ARP190102178 A AR P190102178A AR P190102178 A ARP190102178 A AR P190102178A AR 115883 A1 AR115883 A1 AR 115883A1
Authority
AR
Argentina
Prior art keywords
addiction
psychoactive substances
treatment
pharmaceutical composition
prevention
Prior art date
Application number
ARP190102178A
Other languages
Spanish (es)
Inventor
Fernando Ezquer
Marcelo Ezquer
Jacard Yedy Israel
Gonzlez Mara Elena Quintanilla
Retamales Paola Morales
Marschitz Mario Herrera
Original Assignee
Univ Del Desarrollo
Univ Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Del Desarrollo, Univ Chile filed Critical Univ Del Desarrollo
Publication of AR115883A1 publication Critical patent/AR115883A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente se refiere a una composición farmacéutica para el tratamiento de la adicción crónica a sustancias psicoactivas y/o para prevenir la recaída a la adicción a sustancias psicoactivas, que comprende secretoma y/o exosomas derivados de células madre mesenquimales precondicionadas; y el uso de dicha composición para el tratamiento de la adicción a sustancias psicoactivas y prevención de la recaídas a dicha adicción. Reivindicación 1: Una composición farmacéutica para el tratamiento de la adicción a sustancias psicoactivas y/o para prevenir la recaída a la adicción a sustancias psicoactivas, caracterizada porque comprende entre 0,05 a 50 mg de proteínas totales de exosomas derivados de células madre mesenquimáticas precondicionadas durante su cultivo; y un excipiente farmacéuticamente aceptable. Reivindicación 6: La composición farmacéutica según la reivindicación 1, caracterizada porque las células madre mesenquimáticas se obtienen de tejido adiposo.The present refers to a pharmaceutical composition for the treatment of chronic addiction to psychoactive substances and / or to prevent relapse to addiction to psychoactive substances, comprising secretome and / or exosomes derived from preconditioned mesenchymal stem cells; and the use of said composition for the treatment of addiction to psychoactive substances and prevention of relapses to said addiction. Claim 1: A pharmaceutical composition for the treatment of addiction to psychoactive substances and / or to prevent relapse to addiction to psychoactive substances, characterized in that it comprises between 0.05 to 50 mg of total exosome proteins derived from preconditioned mesenchymal stem cells during its cultivation; and a pharmaceutically acceptable excipient. Claim 6: The pharmaceutical composition according to claim 1, characterized in that the mesenchymal stem cells are obtained from adipose tissue.

ARP190102178A 2018-08-03 2019-08-01 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ADDICTION TO PSYCHOACTIVE SUBSTANCES AND / OR FOR THE PREVENTION OF RELIPS TO SUCH ADDICTION AR115883A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CL2018/050063 WO2020024071A1 (en) 2018-08-03 2018-08-03 Pharmaceutical composition for the treatment of addiction to psychoactive substances and/or the prevention of relapse to said addiction

Publications (1)

Publication Number Publication Date
AR115883A1 true AR115883A1 (en) 2021-03-10

Family

ID=63578894

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190102178A AR115883A1 (en) 2018-08-03 2019-08-01 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ADDICTION TO PSYCHOACTIVE SUBSTANCES AND / OR FOR THE PREVENTION OF RELIPS TO SUCH ADDICTION

Country Status (3)

Country Link
AR (1) AR115883A1 (en)
UY (1) UY38319A (en)
WO (1) WO2020024071A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022014605A (en) 2020-05-19 2022-12-16 Cybin Irl Ltd Deuterated tryptamine derivatives and methods of use.
WO2024007670A1 (en) * 2022-07-07 2024-01-11 Pharward Biotechnology, Inc. Pte. Ltd. Method for treating cocaine addiction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170258843A1 (en) 2016-03-14 2017-09-14 AngioStem, Inc. Stem cell mediated neuroregeneration and neuroprotection
AU2017354272A1 (en) 2016-11-03 2019-05-23 Exostem Biotec Ltd. Mesenchymal stem cells populations, their products, and use thereof

Also Published As

Publication number Publication date
WO2020024071A1 (en) 2020-02-06
UY38319A (en) 2020-02-28

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