AR115755A1 - ISOFORM SELECTIVE HIGH AFFINITY TGFb1 INHIBITORS AND THEIR USES - Google Patents

ISOFORM SELECTIVE HIGH AFFINITY TGFb1 INHIBITORS AND THEIR USES

Info

Publication number
AR115755A1
AR115755A1 ARP190101955A ARP190101955A AR115755A1 AR 115755 A1 AR115755 A1 AR 115755A1 AR P190101955 A ARP190101955 A AR P190101955A AR P190101955 A ARP190101955 A AR P190101955A AR 115755 A1 AR115755 A1 AR 115755A1
Authority
AR
Argentina
Prior art keywords
tgfb1
inhibitors
high affinity
selective high
isoform selective
Prior art date
Application number
ARP190101955A
Other languages
Spanish (es)
Inventor
Justin W Jackson
Susan Lin
Alan Buckler
Gregory J Carven
Christopher Littlefield
Stefan Wawersik
Christopher Chapron
Kevin B Dagbay
Constance Martin
Thomas Schurpf
Allan Capili
Abhishek Datta
Original Assignee
Scholar Rock Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scholar Rock Inc filed Critical Scholar Rock Inc
Publication of AR115755A1 publication Critical patent/AR115755A1/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

En el presente documento se describen anticuerpos monoclonales y fragmentos de unión a antígeno de los mismos capaces de inhibir selectivamente TGFb1 con alta potencia. Composiciones relacionadas, métodos y usos terapéuticos también se describen.Monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGF-1 with high potency are described herein. Related compositions, methods, and therapeutic uses are also described.

ARP190101955A 2018-07-11 2019-07-11 ISOFORM SELECTIVE HIGH AFFINITY TGFb1 INHIBITORS AND THEIR USES AR115755A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862696752P 2018-07-11 2018-07-11

Publications (1)

Publication Number Publication Date
AR115755A1 true AR115755A1 (en) 2021-02-24

Family

ID=74672529

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190101955A AR115755A1 (en) 2018-07-11 2019-07-11 ISOFORM SELECTIVE HIGH AFFINITY TGFb1 INHIBITORS AND THEIR USES

Country Status (1)

Country Link
AR (1) AR115755A1 (en)

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