AR115506A1 - Proteínas de fijación multiespecífica para el tratamiento del cáncer - Google Patents

Proteínas de fijación multiespecífica para el tratamiento del cáncer

Info

Publication number
AR115506A1
AR115506A1 ARP190101568A ARP190101568A AR115506A1 AR 115506 A1 AR115506 A1 AR 115506A1 AR P190101568 A ARP190101568 A AR P190101568A AR P190101568 A ARP190101568 A AR P190101568A AR 115506 A1 AR115506 A1 AR 115506A1
Authority
AR
Argentina
Prior art keywords
proteins
cancer
treatment
binding proteins
specific binding
Prior art date
Application number
ARP190101568A
Other languages
English (en)
Inventor
Vladimir H Voynov
Justin Scheer
Pankaj Gupta
Priyanka Gupta
Philip Nicholas Gorman
Rajkumar Ganesan
Michael Dziegelewski
Paul Adam
Susanne Hipp
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR115506A1 publication Critical patent/AR115506A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Proteínas de fijación a DLL3 / CD3. También ácidos nucleicos que codifican estas proteínas; métodos para preparar estas proteínas; células huésped que expresan o pueden expresar estas proteínas; composiciones que comprenden estas proteínas; y usos de estas proteínas o estas composiciones, en particular, con fines terapéuticos en el campo de las enfermedades cancerosas.
ARP190101568A 2018-06-09 2019-06-07 Proteínas de fijación multiespecífica para el tratamiento del cáncer AR115506A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18176888 2018-06-09

Publications (1)

Publication Number Publication Date
AR115506A1 true AR115506A1 (es) 2021-01-27

Family

ID=62712762

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190101568A AR115506A1 (es) 2018-06-09 2019-06-07 Proteínas de fijación multiespecífica para el tratamiento del cáncer

Country Status (1)

Country Link
AR (1) AR115506A1 (es)

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