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Publication of AR113757A1publicationCriticalpatent/AR113757A1/en
La descripción proporciona proteínas de unión que se unen polipéptidos CD38, p. ej., polipéptidos CD38 humanos y de mono cinomolgo. Por ejemplo, las proteínas de unión pueden ser proteínas de unión monoespecíficas, biespecíficas, o triespecíficas con al menos un dominio de unión a antígeno que se une a un polipéptido CD38. La descripción también proporciona métodos para preparar proteínas de unión que se unen polipéptidos CD38 y usos de tales proteínas de unión.The description provides binding proteins that bind CD38 polypeptides, e.g. eg, human and cynomolgus monkey CD38 polypeptides. For example, the binding proteins can be monospecific, bispecific, or trispecific binding proteins with at least one antigen-binding domain that binds to a CD38 polypeptide. The disclosure also provides methods for preparing binding proteins that bind CD38 polypeptides and uses of such binding proteins.
ARP180102925A2017-10-102018-10-10
ANTI-CD38 ANTIBODIES AND METHODS OF USE
AR113757A1
(en)