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Application filed by Res Institute At Nationwide Children’S HospitalfiledCriticalRes Institute At Nationwide Children’S Hospital
Publication of AR113395A1publicationCriticalpatent/AR113395A1/en
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
La presente descripción se refiere a la administración de virus adenoasociado recombinante (rAAV) de un polinucleótido de neurotrofina 3 (NT-3). La descripción proporciona rAAV y métodos para utilizar la terapia génica rAAV para NT-3 para mejorar la fuerza muscular, estimular el crecimiento muscular y tratar trastornos de desgaste muscular, como la distrofia muscular y la neuropatía de Charcot-Marie-Tooth.The present description refers to the administration of recombinant adeno-associated virus (rAAV) of a neurotrophin 3 (NT-3) polynucleotide. The description provides rAAV and methods for using rAAV gene therapy for NT-3 to improve muscle strength, stimulate muscle growth, and treat muscle wasting disorders, such as muscular dystrophy and Charcot-Marie-Tooth neuropathy.
ARP180103071A2017-10-202018-10-19
METHODS AND MATERIALS FOR NT-3 GENE THERAPY
AR113395A1
(en)
SOLID AGGREGATION MICROPARTICLE, LYOPHILIZED SOLID OR RECONSTITUABLE AGGREGATION MICROPARTICLES, METHOD FOR TREATING AN EYE DISORDER, AND, USE OF SOLID AGGREGATION MICROPARTICLES
[Use of the inventive name established by ISA under Rule 37.2] The use of a complex vitamin composition for the preparation of a medicament for promoting gastrointestinal motility
polynucleotide, nucleic acid vector, pharmaceutical preparation, kit, and methods for making a recombinant adeno-associated viral vector and for treating a disease