AR111971A1 - METHODS FOR TREATING PATIENTS WITH FABRY'S DISEASE WHO HAVE KIDNEY FAILURE - Google Patents
METHODS FOR TREATING PATIENTS WITH FABRY'S DISEASE WHO HAVE KIDNEY FAILUREInfo
- Publication number
- AR111971A1 AR111971A1 ARP180101424A ARP180101424A AR111971A1 AR 111971 A1 AR111971 A1 AR 111971A1 AR P180101424 A ARP180101424 A AR P180101424A AR P180101424 A ARP180101424 A AR P180101424A AR 111971 A1 AR111971 A1 AR 111971A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- patient
- fabry
- disease
- treating patients
- Prior art date
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se proveen métodos para el tratamiento de la enfermedad de Fabry en un paciente que tiene insuficiencia renal y/o proteinuria elevada. Ciertos métodos comprenden administrar al paciente entre aproximadamente 100 y aproximadamente 150 mg de equivalente de base libre de migalastat o una sal del mismo, a una frecuencia de una vez, día por medio. Ciertos métodos también proveen la estabilización de la función renal, reduciendo el índice de masa ventricular izquierda, reduciendo la globotriaosilsfingosina en plasma y/o incrementando la actividad de la a-galactosidasa A en el paciente.Methods are provided for the treatment of Fabry disease in a patient who has renal failure and / or elevated proteinuria. Certain methods comprise administering to the patient between about 100 and about 150 mg of migalastat free base equivalent or a salt thereof, at a frequency of once every other day. Certain methods also provide stabilization of renal function, reducing the left ventricular mass index, reducing plasma globotriaosylsphingosine and / or increasing the activity of α-galactosidase A in the patient.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762512458P | 2017-05-30 | 2017-05-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR111971A1 true AR111971A1 (en) | 2019-09-04 |
Family
ID=64662279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP180101424A AR111971A1 (en) | 2017-05-30 | 2018-05-30 | METHODS FOR TREATING PATIENTS WITH FABRY'S DISEASE WHO HAVE KIDNEY FAILURE |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR111971A1 (en) |
AU (1) | AU2018220047A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR120055A1 (en) * | 2019-06-11 | 2022-02-02 | Amicus Therapeutics Inc | METHODS TO TREAT FABRY'S DISEASE IN PATIENTS WITH KIDNEY FAILURE |
-
2018
- 2018-05-30 AR ARP180101424A patent/AR111971A1/en unknown
- 2018-08-22 AU AU2018220047A patent/AU2018220047A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2018220047A1 (en) | 2018-12-20 |
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