AR111131A1 - RECEIVERS OF CHEMICAL ANTIGENS FOR MELANOMA AND USES OF THESE - Google Patents

RECEIVERS OF CHEMICAL ANTIGENS FOR MELANOMA AND USES OF THESE

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Publication number
AR111131A1
AR111131A1 ARP180100576A ARP180100576A AR111131A1 AR 111131 A1 AR111131 A1 AR 111131A1 AR P180100576 A ARP180100576 A AR P180100576A AR P180100576 A ARP180100576 A AR P180100576A AR 111131 A1 AR111131 A1 AR 111131A1
Authority
AR
Argentina
Prior art keywords
melanoma
genetically modified
lymphocytes
compositions
polynucleotides
Prior art date
Application number
ARP180100576A
Other languages
Spanish (es)
Original Assignee
Kite Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kite Pharma Inc filed Critical Kite Pharma Inc
Publication of AR111131A1 publication Critical patent/AR111131A1/en

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente divulgación se refiere a receptores de antígenos quiméricos (CAR) que comprenden dominios de unión al antígeno que se unen específicamente a células de melanoma, polinucleótidos que codifican dichos CAR, y vectores que comprenden dichos polinucleótidos. Se refiere, además, a células modificadas genéticamente que comprenden dichos polinucleótidos y/o translúcidas con dichos vectores virales y composiciones que incluyen múltiples linfocitos T modificados genéticamente. También se refiere a métodos para producir dichas composiciones y linfocitos T modificados genéticamente y usos (para tratar un melanoma) de dichas composiciones y linfocitos T modificados genéticamente.The present disclosure relates to chimeric antigen (CAR) receptors comprising antigen binding domains that specifically bind to melanoma cells, polynucleotides encoding said CAR, and vectors comprising said polynucleotides. It also refers to genetically modified cells comprising said polynucleotides and / or translucent with said viral vectors and compositions that include multiple genetically modified T lymphocytes. It also refers to methods for producing said compositions and genetically modified T lymphocytes and uses (for treating a melanoma) of said compositions and genetically modified T lymphocytes.

ARP180100576A 2017-03-13 2018-03-13 RECEIVERS OF CHEMICAL ANTIGENS FOR MELANOMA AND USES OF THESE AR111131A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762470703P 2017-03-13 2017-03-13

Publications (1)

Publication Number Publication Date
AR111131A1 true AR111131A1 (en) 2019-06-05

Family

ID=67060520

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180100576A AR111131A1 (en) 2017-03-13 2018-03-13 RECEIVERS OF CHEMICAL ANTIGENS FOR MELANOMA AND USES OF THESE

Country Status (1)

Country Link
AR (1) AR111131A1 (en)

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