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Application filed by Iovance Biotherapeutics IncfiledCriticalIovance Biotherapeutics Inc
Publication of AR110733A1publicationCriticalpatent/AR110733A1/en
La presente proporciona mejores métodos y/o métodos acortados para expandir TILs y producir poblaciones terapéuticas de TILs, incluyendo métodos para expandir las poblaciones de TILs en un sistema cerrado que llevan a una mayor eficacia, mayor fenotipo y mayor salud metabólica de los TILs en un período de tiempo más corto, mientras permite una contaminación microbiana reducida así como menores costos. Estos TILs se usan en regímenes de tratamiento terapéuticos.This provides better methods and / or shortened methods to expand TILs and produce therapeutic populations of TILs, including methods to expand populations of TILs in a closed system that lead to greater efficacy, greater phenotype and greater metabolic health of TILs in a shorter period of time, while allowing reduced microbial contamination as well as lower costs. These TILs are used in therapeutic treatment regimens.
ARP180100035A2017-03-292018-01-05
PROCESSES TO PRODUCE TUMOR INFILTRATING LYMPHOCYTES AND USES OF THE SAME IN IMMUNOTHERAPY
AR110733A1
(en)