AR107209A1

AR107209A1 - INTRAVAGINAL DEVICE CONTAINING HORMONES FOR THE SYNCHRONIZATION OF CELO AND OVULATION IN MAMMALS OF ZOOTECHNICAL INTEREST

Info

Publication number: AR107209A1
Application number: ARP170100058A
Authority: AR
Original assignee: Scandolo Lucini Diego German
Priority date: 2017-01-10
Filing date: 2017-01-10
Publication date: 2018-04-11

Abstract

Es un dispositivo concebido para ser utilizado con la finalidad de mantener los niveles de progesterona en valores cercanos o superiores de 2 ng/mL en hembras que ingresan a un protocolo de sincronización de celo u ovulación, con el objetivo de incrementar las tasas de inseminación y concepción, las que podrán ser vaca, oveja, cabra, búfalo o yegua y equivalentes. Comprende un cuerpo cilíndrico y hueco, sustancialmente maleable y con memoria elástica, constituido por el moldeo de una silicona vulcanizada, que contiene la progesterona, definiendo una geometría variable capaz de permanecer en la cavidad vaginal de la hembra seleccionada, adaptándose a la configuración interna de la vagina y a las contracciones que se producen en la misma. El mismo presenta una superficie externa de entre 30 cm² y 300 cm² y contiene un peso de progesterona de entre un 0,3% a 10% en relación al peso del dispositivo. La pared de silicona vulcanizada está revestida con una cubierta laminar biocompatible, de material sintético o biológico. El peso del dispositivo inventado varía entre 20 g y 90 g, donde se incluye entre 0,5 g y 1,5 g de progesterona, cuya pared podrá presentar un espesor de entre 2 mm a 20 mm y un diámetro de entre 2 cm a 10 cm.It is a device designed to be used for the purpose of maintaining progesterone levels at values close to or greater than 2 ng / mL in females that enter a heat or ovulation synchronization protocol, with the aim of increasing insemination rates and conception, which may be cow, sheep, goat, buffalo or mare and equivalent. It comprises a cylindrical and hollow body, substantially malleable and with elastic memory, constituted by the molding of a vulcanized silicone, which contains the progesterone, defining a variable geometry capable of remaining in the vaginal cavity of the selected female, adapting to the internal configuration of the vagina and the contractions that occur in it. It has an external surface area between 30 cm² and 300 cm² and contains a progesterone weight of between 0.3% and 10% in relation to the weight of the device. The vulcanized silicone wall is coated with a biocompatible sheet cover, made of synthetic or biological material. The weight of the invented device varies between 20 g and 90 g, which includes between 0.5 g and 1.5 g of progesterone, whose wall may have a thickness between 2 mm to 20 mm and a diameter between 2 cm to 10 cm .