AR107075A1 - ANTI-TL1A / ANTI-TNF-a BISPECIFIC ANTIGEN BIND PROTEINS AND ITS USES - Google Patents
ANTI-TL1A / ANTI-TNF-a BISPECIFIC ANTIGEN BIND PROTEINS AND ITS USESInfo
- Publication number
- AR107075A1 AR107075A1 ARP160103884A ARP160103884A AR107075A1 AR 107075 A1 AR107075 A1 AR 107075A1 AR P160103884 A ARP160103884 A AR P160103884A AR P160103884 A ARP160103884 A AR P160103884A AR 107075 A1 AR107075 A1 AR 107075A1
- Authority
- AR
- Argentina
- Prior art keywords
- tl1a
- tnf
- binding proteins
- antigen binding
- bispecific antigen
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente hace referencia a proteínas de unión al antígeno que se unen a TL1A (citocina miembro de la familia de TNF-a), inclusive proteínas de unión al antígeno biespecífico (p. ej.,anticuerpos) a TL1A y TNF-a. Dichos anticuerpos biespecíficos pueden estar en un formato de inmunoglobulina tetramérica convencional, en el cual un par de cadena pesada-cadena ligera del anticuerpo se dirige al TL1A y el otro a TNF-a. Las proteínas de unión al antígeno biespecífico pueden estar incluidas también en una fusión de IgG-scFv, donde un anticuerpo tetramérico convencional dirigido a un antígeno se fusiona con un par de unidades Fv de cadena simple dirigido al otro. Hace referencia también a los usos de las proteínas de unión a anti-TL1A y las proteínas de unión al antígeno de anti-TL1A / anti-TNF-a (factor de necrosis tumoral a) y las formulaciones farmacéuticas de estas. Ácidos nucleicos; vectores; célula; método.It refers to antigen binding proteins that bind to TL1A (cytokine member of the TNF-a family), including bispecific antigen binding proteins (eg, antibodies) to TL1A and TNF-a. Such bispecific antibodies may be in a conventional tetrameric immunoglobulin format, in which one heavy chain-light chain pair of the antibody is directed to TL1A and the other to TNF-a. Bispecific antigen binding proteins may also be included in an IgG-scFv fusion, where a conventional tetrameric antibody directed to one antigen is fused with a pair of single chain Fv units directed to the other. It also refers to the uses of anti-TL1A binding proteins and anti-TL1A / anti-TNF-a antigen binding proteins (tumor necrosis factor a) and their pharmaceutical formulations. Nucleic acids; vectors; cell; method.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562268432P | 2015-12-16 | 2015-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR107075A1 true AR107075A1 (en) | 2018-03-21 |
Family
ID=61768598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP160103884A AR107075A1 (en) | 2015-12-16 | 2016-12-16 | ANTI-TL1A / ANTI-TNF-a BISPECIFIC ANTIGEN BIND PROTEINS AND ITS USES |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR107075A1 (en) |
| TN (1) | TN2018000212A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114450397A (en) * | 2019-08-01 | 2022-05-06 | 纪念斯隆-凯特琳癌症中心 | Cells for improved immunotherapy and uses thereof |
-
2016
- 2016-12-14 TN TNP/2018/000212A patent/TN2018000212A1/en unknown
- 2016-12-16 AR ARP160103884A patent/AR107075A1/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114450397A (en) * | 2019-08-01 | 2022-05-06 | 纪念斯隆-凯特琳癌症中心 | Cells for improved immunotherapy and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| TN2018000212A1 (en) | 2019-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2018001596A1 (en) | Bispecific antigen binding proteins of anti-tl1a / anti-tnf-a and their uses | |
| DOP2018000259A (en) | BISPECIFIC UNION PROTEINS THAT JOIN AN IMMUNOMODULATORY PROTEIN AND A TUMORAL ANTIGEN | |
| DOP2021000005A (en) | BINDING PROTEINS TO PD1 AND / OR LAG3 | |
| GT201700162A (en) | ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BIESPECIFIC ANTIBODIES THAT SPECIFICALLY JOIN CD3 AND / OR CD123 | |
| CO2018012415A2 (en) | Specific binding proteins and uses thereof | |
| CO2019003945A2 (en) | Bispecific heterodimeric fusion proteins containing fc il-15 / il-15rα fusion proteins and pd-1 antibody fragments | |
| CL2018001326A1 (en) | Ctla4 binding proteins. | |
| CL2018000502A1 (en) | Bispecific antibodies for pd1 and tim3 useful as immunomodulators or in the treatment of cancer. | |
| CR20170511A (en) | HETERODIMERIC ANTIBODIES THAT JOIN CD3 AND TUMOR ANTIGENS. | |
| DOP2019000011A (en) | BISPECIFIC ANTIBODY TYPE UNION PROTEINS THAT SPECIFICALLY JOIN CD3 AND CD123 | |
| CU20170074A7 (en) | HETERODIMERIC ANTIBODIES THAT JOIN CD3 AND TUMOR ANTIGENS | |
| AR106555A1 (en) | ANTI-IL1RAP ANTIBODIES, BINDING SPECIFIC MOLECULES THAT JOIN IL1RAP AND CD3, AND USES OF THESE | |
| CL2017002881A1 (en) | Anti-fcrn antibodies | |
| CL2018003515A1 (en) | Anti-gitr antibodies and their uses. | |
| CY1122214T1 (en) | ANTIBODIES SPECIFIC TO TON FCRN | |
| CO2019003759A2 (en) | Antibodies that bind to the zika virus envelope protein and uses thereof | |
| AR095268A1 (en) | HUMAN ANTIBODIES THAT JOIN THE HUMAN NECROSIS FACTOR (TNF-a) AND METHODS TO PREPARE THEM | |
| AR118763A1 (en) | MONOCLONAL ANTIBODY SPECIFICALLY JOINING GITR | |
| UY37630A (en) | PHARMACEUTICAL COMBINATION, KIT, GUEST CELL THAT PRODUCES IT AND ITS USE IN METHODS FOR CANCER TREATMENT | |
| AR107075A1 (en) | ANTI-TL1A / ANTI-TNF-a BISPECIFIC ANTIGEN BIND PROTEINS AND ITS USES | |
| EA201892124A1 (en) | DNA STRUCTURES OF ANTIBODIES AND METHODS OF THEIR APPLICATION | |
| MX2020004220A (en) | Anti-glyco-muc1 antibodies and their uses. | |
| AR105633A1 (en) | HETEROMERS UNDERSTANDING FUSION PROTEINS WITH ANTIBODY DOMAINS | |
| AR107834A1 (en) | ANTIBODIES THAT JOIN THE TUMOR NECROSIS FACTOR INDICATED BY GLUCOCORTICOIDS (GITR), METHODS AND USES |