AR105793A1 - METHODS AND COMPOSITIONS FOR IMMUNE PROTECTION AGAINST E. COLI PATHOGENIC EXTRAINTESTINAL - Google Patents

METHODS AND COMPOSITIONS FOR IMMUNE PROTECTION AGAINST E. COLI PATHOGENIC EXTRAINTESTINAL

Info

Publication number
AR105793A1
AR105793A1 ARP160102574A ARP160102574A AR105793A1 AR 105793 A1 AR105793 A1 AR 105793A1 AR P160102574 A ARP160102574 A AR P160102574A AR P160102574 A ARP160102574 A AR P160102574A AR 105793 A1 AR105793 A1 AR 105793A1
Authority
AR
Argentina
Prior art keywords
compositions
methods
expec
protection against
extraintestinal
Prior art date
Application number
ARP160102574A
Other languages
Spanish (es)
Original Assignee
Glycovaxyn Ag
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycovaxyn Ag, Janssen Pharmaceuticals Inc filed Critical Glycovaxyn Ag
Publication of AR105793A1 publication Critical patent/AR105793A1/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describen composiciones y métodos para inducir una respuesta inmunológica contra Escherichia coli patogénica extraintestinal (ExPEC) para así proporcionar protección inmunológica contra enfermedades asociadas con ExPEC. En particular, se describen composiciones y métodos para usar conjugados de antígenos polisacáridos de E. coli O25B, O1A, O2 y O6A unidos de forma covalente con una proteína portadora de exotoxina A detoxificada de Pseudomonas aeruginosa (EPA) como vacunas para la prevención de enfermedades invasivas por ExPEC provocadas por los serotipos ExPEC O1A, O2, O6A y O25B.Compositions and methods for inducing an immune response against extraintestinal pathogenic Escherichia coli (ExPEC) are described in order to provide immune protection against diseases associated with ExPEC. In particular, compositions and methods for using conjugates of E. coli O25B, O1A, O2 and O6A polysaccharide antigens covalently linked with a detoxified carrier protein of Pseudomonas aeruginosa A (exotoxin A) as vaccines for disease prevention are described invasive by ExPEC caused by the ExPEC serotypes O1A, O2, O6A and O25B.

ARP160102574A 2015-08-24 2016-08-23 METHODS AND COMPOSITIONS FOR IMMUNE PROTECTION AGAINST E. COLI PATHOGENIC EXTRAINTESTINAL AR105793A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562209091P 2015-08-24 2015-08-24

Publications (1)

Publication Number Publication Date
AR105793A1 true AR105793A1 (en) 2017-11-08

Family

ID=60451256

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160102574A AR105793A1 (en) 2015-08-24 2016-08-23 METHODS AND COMPOSITIONS FOR IMMUNE PROTECTION AGAINST E. COLI PATHOGENIC EXTRAINTESTINAL

Country Status (1)

Country Link
AR (1) AR105793A1 (en)

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