AR105558A1 - ANTIBODY CONSTRUCTS FOR DLL3 AND CD3 - Google Patents
ANTIBODY CONSTRUCTS FOR DLL3 AND CD3Info
- Publication number
- AR105558A1 AR105558A1 ARP160102337A ARP160102337A AR105558A1 AR 105558 A1 AR105558 A1 AR 105558A1 AR P160102337 A ARP160102337 A AR P160102337A AR P160102337 A ARP160102337 A AR P160102337A AR 105558 A1 AR105558 A1 AR 105558A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibody construct
- dll3
- polynucleotide
- antibody constructs
- binds
- Prior art date
Links
Abstract
La presente solicitud se refiere a un constructo de anticuerpo biespecífico que comprende un primer dominio de unión que se une a DLL3 humana en la superficie de una célula diana y un segundo dominio de unión que se une a CD3 humano en la superficie de una célula T. Además, la solicitud provee un polinucleótido que codifica el constructo de anticuerpo, un vector que comprende dicho polinucleótido y una célula hospedante transformada o transfectada con dicho polinucleótido o vector. Adicionalmente, la solicitud provee un proceso para la producción del constructo de anticuerpo de la solicitud, un uso médico de dicho constructo de anticuerpo y un kit que comprende dicho constructo de anticuerpo.The present application relates to a bispecific antibody construct comprising a first binding domain that binds to human DLL3 on the surface of a target cell and a second binding domain that binds to human CD3 on the surface of a T cell In addition, the application provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Additionally, the application provides a process for the production of the antibody construct of the application, a medical use of said antibody construct and a kit comprising said antibody construct.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562199930P | 2015-07-31 | 2015-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR105558A1 true AR105558A1 (en) | 2017-10-18 |
Family
ID=60245273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160102337A AR105558A1 (en) | 2015-07-31 | 2016-08-01 | ANTIBODY CONSTRUCTS FOR DLL3 AND CD3 |
Country Status (1)
Country | Link |
---|---|
AR (1) | AR105558A1 (en) |
-
2016
- 2016-08-01 AR ARP160102337A patent/AR105558A1/en unknown
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