Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothena Biosciences Ltd, Univ Health NetworkfiledCriticalProthena Biosciences Ltd
Publication of AR103549A1publicationCriticalpatent/AR103549A1/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Peptides Or Proteins
(AREA)
Abstract
Anticuerpos que se unen de forma específica a la transtiretina (TTR). Los anticuerpos se pueden utilizar para tratar o efectuar la profilaxis de las enfermedades o trastornos asociados con la acumulación de TTR o la acumulación de depósitos de TTR (p. ej., amiloidosis de TTR). Los anticuerpos también se pueden utilizar para diagnosticar la amiloidosis de TTR e inhibir o reducir la agregación de TTR; entre otras aplicaciones. Ácido nucleico; vector; célula; método.Antibodies that specifically bind to transthyretin (TTR). Antibodies can be used to treat or effect the prophylaxis of diseases or disorders associated with the accumulation of TTR or the accumulation of TTR deposits (eg, TTR amyloidosis). Antibodies can also be used to diagnose TTR amyloidosis and inhibit or reduce TTR aggregation; Among other applications. Nucleic acid; vector; cell; method.