AR103030A1 - IMMUNOGEN COMPOSITION - Google Patents
IMMUNOGEN COMPOSITIONInfo
- Publication number
- AR103030A1 AR103030A1 ARP150104087A ARP150104087A AR103030A1 AR 103030 A1 AR103030 A1 AR 103030A1 AR P150104087 A ARP150104087 A AR P150104087A AR P150104087 A ARP150104087 A AR P150104087A AR 103030 A1 AR103030 A1 AR 103030A1
- Authority
- AR
- Argentina
- Prior art keywords
- vaccine
- immunogenic composition
- years
- age
- saponin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Reivindicación 1: Una composición inmunógena, por ejemplo de vacuna, que comprende un antígeno gE de virus de varicela zóster (VZV) truncado para eliminar la región de anclaje carboxi terminal, en combinación con un coadyuvante que comprende una saponina, un agonista de TLR-4 y liposomas para su uso en un procedimiento para la protección frente a, o la prevención de, herpes zóster (HZ) y/o neuralgia postherpética (PHN) durante al menos 4 años después de la vacunación. Reivindicación 2: Una composición inmunógena, por ejemplo de vacuna, según la reivindicación 1, para su uso en un procedimiento para la protección frente a, o la prevención de, herpes zóster (HZ) y/o neuralgia postherpética durante al menos 5, 6, 7, 8, 9, 10, 12 ó 15 años después de la vacunación. Reivindicación 5: Composición inmunógena, por ejemplo de vacuna, según cualquiera de las reivindicaciones anteriores, para su uso en un sujeto humano de ³ 50 años de edad, ³ 60 años de edad, ³ 70 años de edad, entre 50 y 59 años de edad o entre 60 y 69 años de edad. Reivindicación 13: Una composición inmunógena, por ejemplo de vacuna, según cualquiera de las reivindicaciones anteriores, en la que el procedimiento comprende administrar 2 dosis de la composición de vacuna a un individuo. Reivindicación 17: Una composición inmunógena, por ejemplo de vacuna, según cualquiera de las reivindicaciones anteriores, en la que el antígeno gE de VZV no está en forma de una proteína de fusión. Reivindicación 20: Una composición inmunógena, por ejemplo de vacuna, según cualquiera de las reivindicaciones anteriores, en la que el antígeno de VZV está presente en una cantidad de 50 mg por dosis. Reivindicación 21: Una composición inmunógena, por ejemplo de vacuna, según cualquiera de las reivindicaciones anteriores, en la que la saponina es QS21. Reivindicación 22: Una composición inmunógena, por ejemplo de vacuna, según cualquiera de las reivindicaciones anteriores, en la que la saponina tal como QS21 está presente en una cantidad de 1 a 100 mg, tal como 25 mg ó 50 mg por dosis.Claim 1: An immunogenic composition, for example a vaccine, comprising a truncated chickenpox virus (VZV) gE antigen to remove the carboxy terminal anchor region, in combination with an adjuvant comprising a saponin, a TLR-agonist. 4 and liposomes for use in a procedure for protection against, or prevention of, shingles (HZ) and / or postherpetic neuralgia (PHN) for at least 4 years after vaccination. Claim 2: An immunogenic composition, for example of a vaccine, according to claim 1, for use in a method for the protection against, or the prevention of, shingles (HZ) and / or postherpetic neuralgia for at least 5, 6 , 7, 8, 9, 10, 12 or 15 years after vaccination. Claim 5: Immunogenic composition, for example of vaccine, according to any of the preceding claims, for use in a human subject of ³ 50 years of age, ³ 60 years of age, ³ 70 years of age, between 50 and 59 years of age. Age or between 60 and 69 years old. Claim 13: An immunogenic composition, for example of a vaccine, according to any of the preceding claims, wherein the method comprises administering 2 doses of the vaccine composition to an individual. Claim 17: An immunogenic composition, for example of a vaccine, according to any of the preceding claims, wherein the VZV gE antigen is not in the form of a fusion protein. Claim 20: An immunogenic composition, for example of a vaccine, according to any of the preceding claims, wherein the VZV antigen is present in an amount of 50 mg per dose. Claim 21: An immunogenic composition, for example of a vaccine, according to any of the preceding claims, wherein the saponin is QS21. Claim 22: An immunogenic composition, for example of a vaccine, according to any of the preceding claims, wherein saponin such as QS21 is present in an amount of 1 to 100 mg, such as 25 mg or 50 mg per dose.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201422686 | 2014-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR103030A1 true AR103030A1 (en) | 2017-04-12 |
Family
ID=52807451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150104087A AR103030A1 (en) | 2014-12-18 | 2015-12-15 | IMMUNOGEN COMPOSITION |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR103030A1 (en) |
BE (1) | BE1022523B1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4074336A1 (en) * | 2019-12-13 | 2022-10-19 | Grand Theravac Life Science (Nanjing) Co., Ltd. | Pharmaceutical composition and use thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0504436D0 (en) * | 2005-03-03 | 2005-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
-
2014
- 2014-12-31 BE BE2014/5165A patent/BE1022523B1/en active
-
2015
- 2015-12-15 AR ARP150104087A patent/AR103030A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE1022523B1 (en) | 2016-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2019003264A1 (en) | Formulations for vaccines against neoplasia and methods for preparing the same. (divisional request 201703151) | |
HRP20210608T1 (en) | Methods and compositions for inducing protective immunity against human immunodeficiency virus infection | |
CO2018005258A2 (en) | Herpes simplex virus vaccine | |
CR20180027A (en) | NEW PEPTIDES AND NEW COMBINATIONS OF PEPTIDES FOR USE IN THE SAME THERAPY AGAINST OVARY EPITELIAL CANCER AND OTHER TYPES OF CANCER. | |
NZ616304A (en) | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses | |
CO6501190A2 (en) | PCSK9 VACCINE | |
CO6331297A2 (en) | NEW ADVANCING COMPOSITIONS | |
PH12017501370A1 (en) | Bivalent swine influenza virus vaccine | |
AR108829A1 (en) | VACCINE AGAINST INFECTIOUS BRONCHITIS VIRUS | |
AR093712A1 (en) | IMMUNOGEN COMPOSITION, VACCINE, USE AND PROCEDURE FOR PREVENTION OR TREATMENT | |
BR112017003462A2 (en) | attenuated bovine coronavirus, vaccine, and method of vaccination of a bovine. | |
JP2018500322A5 (en) | ||
BR112014023414A2 (en) | recombinant equine herpesvirus-1 vaccine containing a mutant glycoprotein and its uses | |
CO6561819A2 (en) | VECTORS FOR VACCINES AND METHOD FOR POWERING IMMUNE RESPONSES | |
PH12015501875A1 (en) | Acellular pertussis vaccine | |
MX2016001695A (en) | Combination immunogenic compositions. | |
MX2017013564A (en) | Glucopyranosyl lipid a and peanut allergen formulations for sublingual administration. | |
AR099960A1 (en) | PROCEDURES AND PHARMACEUTICAL COMPOSITION TO INDUCE AN IMMUNE RESPONSE | |
MX2013003245A (en) | Bvdv vaccine. | |
BR112013001946A2 (en) | inactivated varicella zoster virus, pharmaceutical composition, method for preparing an inactivated varicella zoster virus, vaccine, and method for treating herpes zoster in an individual | |
AR104271A1 (en) | VACCINE AGAINST PAPERAS BASED ON VIRUS JERYL LYNN 2 RECOMBINANT | |
AR103030A1 (en) | IMMUNOGEN COMPOSITION | |
AR093530A1 (en) | VACCINATION ASSISTANT, PREPARATION, AND VACCINES CONTAINING IT | |
AR102250A1 (en) | COMPOSITIONS OF VACCINES WITH REDUCED FOAM FORMATION | |
AR106501A1 (en) | VACCINE ADJUSTER AND COMPOSITION CONTAINING IT |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |