AR096803A1 - BENCIL-1H-PIRAZOLO [3,4-B] PIRIDINES AND ITS USE - Google Patents

BENCIL-1H-PIRAZOLO [3,4-B] PIRIDINES AND ITS USE

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Publication number
AR096803A1
AR096803A1 ARP140102484A ARP140102484A AR096803A1 AR 096803 A1 AR096803 A1 AR 096803A1 AR P140102484 A ARP140102484 A AR P140102484A AR P140102484 A ARP140102484 A AR P140102484A AR 096803 A1 AR096803 A1 AR 096803A1
Authority
AR
Argentina
Prior art keywords
fluorine
represents hydrogen
oxides
prevention
salts
Prior art date
Application number
ARP140102484A
Other languages
Spanish (es)
Inventor
Dr Gromov Alexey
Dr Brockschnieder Damian
Prof Dr Stasch Johannes
Peter - Dr Marquardt Tobias
Dr Tersteegen Adrian
Dr Wunder Frank
Dr Redlich Gorden
Dr Lang Dieter
Min Dr Li Volkhart
Jian - Dr Follmann Markus
Dr Vakalopoulos Alexandros
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of AR096803A1 publication Critical patent/AR096803A1/en

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente solicitud se refiere a bencil-1H-pirazoIo[3,4-b]piridinas, a procedimientos para su preparación, a su uso solas o en combinaciones para el tratamiento y/o la prevención de enfermedades así como a su uso para la preparación de medicamentos para el tratamiento y/o la prevención de enfermedades, en particular para el tratamiento y/o la prevención de enfermedades cardiocirculatorias. Reivindicación 1: Compuesto de la fórmula (1) en la que R¹ representa hidrógeno o flúor, R² representa hidrógeno o flúor, R³ representa hidrógeno, cloro o flúor, R⁴ representa hidrógeno, cloro, flúor o metilo, con la condición que al menos dos de los restos R¹, R², R³ o R⁴ sean diferentes de hidrógeno, R⁵ representa hidrógeno o flúor, R⁶ representa metilo, R⁷ representa metilo, o R⁶ y R⁷ junto con el átomo de carbono al que están unidos, forman un anillo de ciclopropilo, así como sus N-óxidos, sales, solvatos, sales de los N-óxidos y solvatos de los N-óxidos y sales.The present application relates to benzyl-1 H -pyrazo [3,4-b] pyridines, processes for their preparation, their use alone or in combinations for the treatment and / or prevention of diseases as well as their use for preparation of medicaments for the treatment and / or prevention of diseases, in particular for the treatment and / or prevention of cardiocirculatory diseases. Claim 1: Compound of the formula (1) wherein R¹ represents hydrogen or fluorine, R² represents hydrogen or fluorine, R³ represents hydrogen, chlorine or fluorine, R⁴ represents hydrogen, chlorine, fluorine or methyl, with the condition that at least two of the residues R,, R², R³ or R⁴ are different from hydrogen, R⁵ represents hydrogen or fluorine, R⁶ represents methyl, R⁷ represents methyl, or R⁶ and R⁷ together with the carbon atom to which they are attached, form a cyclopropyl ring, as well as its N-oxides, salts, solvates, salts of the N-oxides and solvates of the N-oxides and salts.

ARP140102484A 2013-07-10 2014-07-03 BENCIL-1H-PIRAZOLO [3,4-B] PIRIDINES AND ITS USE AR096803A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13175889 2013-07-10

Publications (1)

Publication Number Publication Date
AR096803A1 true AR096803A1 (en) 2016-02-03

Family

ID=48747469

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140102484A AR096803A1 (en) 2013-07-10 2014-07-03 BENCIL-1H-PIRAZOLO [3,4-B] PIRIDINES AND ITS USE

Country Status (2)

Country Link
AR (1) AR096803A1 (en)
MA (1) MA38775A1 (en)

Also Published As

Publication number Publication date
MA38775A1 (en) 2017-07-31

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