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Application filed by Smithkline Beecham Biologicals S AfiledCriticalSmithkline Beecham Biologicals S A
Priority to ARP130104433ApriorityCriticalpatent/AR093687A2/en
Publication of AR093687A2publicationCriticalpatent/AR093687A2/en
La presente se refiere a composiciones adyuvantes que son adecuadas para ser usadas en vacunas. En particular, las composiciones adyuvantes de la presente comprende una saponina y un oligonucleótido inmunoestimulante, opcionalmente con un vehículo. También se proporcionan por la presente, vacunas que comprenden los adyuvantes de la presente y un antígeno. Además se proporcionan procedimientos de fabricación de los adyuvantes y las vacunas de la presente y su uso como medicamentos. También se proporcionan los procedimientos de tratamiento de un individuo susceptible a o que padezca una enfermedad por la administración de las vacunas de la presente.This refers to adjuvant compositions that are suitable for use in vaccines. In particular, the adjuvant compositions herein comprise a saponin and an immunostimulatory oligonucleotide, optionally with a carrier. Also provided herein are vaccines comprising the adjuvants herein and an antigen. In addition, manufacturing procedures for adjuvants and vaccines are provided herein and their use as medicaments. The treatment procedures of an individual susceptible to or suffering from a disease by the administration of the vaccines herein are also provided.
Pharmaceutical composition in the form of a tablet comprising atazanavir and cobicistat; preparation procedure; and use of the composition to prepare a medicament useful for treating human immunodeficiency virus (hiv) infection.