AR093675A1 - A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF ROTIGOTINA - Google Patents

A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF ROTIGOTINA

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Publication number
AR093675A1
AR093675A1 ARP130104421A ARP130104421A AR093675A1 AR 093675 A1 AR093675 A1 AR 093675A1 AR P130104421 A ARP130104421 A AR P130104421A AR P130104421 A ARP130104421 A AR P130104421A AR 093675 A1 AR093675 A1 AR 093675A1
Authority
AR
Argentina
Prior art keywords
transdermal administration
adhesives
rotigotine
styrene
adhesive matrix
Prior art date
Application number
ARP130104421A
Other languages
Spanish (es)
Original Assignee
Amarin Tech S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amarin Tech S A filed Critical Amarin Tech S A
Priority to ARP130104421A priority Critical patent/AR093675A1/en
Publication of AR093675A1 publication Critical patent/AR093675A1/en

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Abstract

Reivindicación 1: Un dispositivo para la administración transdérmica de rotigotina que comprende una capa de matriz adhesiva, una lámina de soporte y una lámina de despegue caracterizado porque dicha matriz adhesiva comprende rotigotina, un polímero adhesivo seleccionado de entre los adhesivos siliconados, los adhesivos acrílicos, los adhesivos de poliisobutilenos y los adhesivos de copolímeros en bloque del tipo estireno-isopreno-estireno o estireno-butirenoestireno o una mezcla de dichos adhesivos y un copolímero de polietilenglicol, polivinilcaprolactamo y polivinilacetato. Reivindicación 10: Un dispositivo para la administración transdérmica de rotigotina de acuerdo con cualquiera de las reivindicaciones anteriores, caracterizado porque el dispositivo también comprende un antioxidante y un promotor de la permeación. Reivindicación 12: Un dispositivo para la administración transdérmica de rotigotina de acuerdo con la reivindicación anterior, caracterizado porque el promotor de la permeación es la N-metil-2-pirrolidona, la cual se encuentra presente en la matriz adhesiva en una concentración de entre aproximadamente 2,5% y aproximadamente 6%. Reivindicación 13: Un dispositivo para la administración transdérmica de rotigotina de acuerdo con cualquiera de las reivindicaciones 10, 11 y 12, caracterizado porque el antioxidante es el palmitato de ascorbilo.Claim 1: A device for transdermal administration of rotigotine comprising an adhesive matrix layer, a support sheet and a peel sheet characterized in that said adhesive matrix comprises rotigotine, an adhesive polymer selected from among the silicone adhesives, acrylic adhesives, polyisobutylenes adhesives and block copolymer adhesives of the styrene-isoprene-styrene or styrene-butyrene styrene type or a mixture of said adhesives and a polyethylene glycol, polyvinylcaprolactam and polyvinylacetate copolymer. Claim 10: A device for transdermal administration of rotigotine according to any of the preceding claims, characterized in that the device also comprises an antioxidant and a permeation promoter. Claim 12: A device for transdermal administration of rotigotine according to the preceding claim, characterized in that the permeation promoter is N-methyl-2-pyrrolidone, which is present in the adhesive matrix at a concentration of between approximately 2.5% and approximately 6%. Claim 13: A device for transdermal administration of rotigotine according to any of claims 10, 11 and 12, characterized in that the antioxidant is ascorbyl palmitate.

ARP130104421A 2013-11-29 2013-11-29 A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF ROTIGOTINA AR093675A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP130104421A AR093675A1 (en) 2013-11-29 2013-11-29 A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF ROTIGOTINA

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP130104421A AR093675A1 (en) 2013-11-29 2013-11-29 A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF ROTIGOTINA

Publications (1)

Publication Number Publication Date
AR093675A1 true AR093675A1 (en) 2015-06-17

Family

ID=56117240

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130104421A AR093675A1 (en) 2013-11-29 2013-11-29 A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF ROTIGOTINA

Country Status (1)

Country Link
AR (1) AR093675A1 (en)

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