AR090098A1 - FUNGICIDE PIRAZOLS - Google Patents

FUNGICIDE PIRAZOLS

Info

Publication number
AR090098A1
AR090098A1 ARP130100510A ARP130100510A AR090098A1 AR 090098 A1 AR090098 A1 AR 090098A1 AR P130100510 A ARP130100510 A AR P130100510A AR P130100510 A ARP130100510 A AR P130100510A AR 090098 A1 AR090098 A1 AR 090098A1
Authority
AR
Argentina
Prior art keywords
ring
alkyl
haloalkyl
independently selected
optionally substituted
Prior art date
Application number
ARP130100510A
Other languages
Spanish (es)
Inventor
Keith Long Jeffrey
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of AR090098A1 publication Critical patent/AR090098A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

Se describen composiciones que contienen los compuestos de la fórmula (1) y métodos para controlar enfermedades de las plantas causadas por un patógeno fúngico; el método comprende aplicar una cantidad eficaz de un compuesto o una composición de la presente. Reivindicación 1: Un compuesto seleccionado de la fórmula (1), N-óxidos y sales de estos, caracterizado porque Q¹ es un anillo o sistema anular de fenilo o naftalenilo; cada anillo o sistema anular está sustituido opcionalmente con hasta 5 sustituyentes seleccionados independientemente de R³; o un anillo heterocíclico de 5 a 6 miembros totalmente insaturado o un sistema anular bicíclico heteroaromático de 8 a 10 miembros; cada anillo o sistema anular contiene miembros de anillo seleccionados de átomos de carbono y hasta 4 heteroátomos seleccionados independientemente de hasta 2 átomos de O, hasta 2 átomos de S y hasta 4 átomos de N, en donde hasta 3 miembros de anillo de carbono se seleccionan independientemente de C(=O) y C(=S) y los miembros de anillo de átomos de azufre se seleccionan independientemente de S(=O)ᵘ(=NR¹⁴)ᵛ; cada anillo o sistema anular está sustituido opcionalmente con hasta 5 sustituyentes seleccionados independientemente de R³ en miembros de anillo de átomos de carbono y seleccionados de ciano, alquilo C₁₋₆, alquenilo C₂₋₆, alquinilo C₂₋₆, cicloalquilo C₃₋₆, alcoxi C₁₋₆, alcoxialquilo C₂₋₆, alquilcarbonilo C₂₋₆, alcoxicarbonilo C₂₋₆, alquilaminoalquilo C₂₋₆ y dialquilaminoalquilo C₃₋₆ en miembros de anillo de átomos de nitrógeno; Q² es un anillo o sistema anular de fenilo o naftalenilo; cada anillo o sistema anular está sustituido opcionalmente con hasta 5 sustituyentes seleccionados independientemente de R³; o un anillo heterocíclico de 4, 5 ó 6 miembros saturado, parcialmente insaturado o totalmente insaturado o un sistema anular bicíclico heteroaromático de 8 a 10 miembros; cada anillo o sistema anular contiene miembros de anillo seleccionados de átomos de carbono y hasta 4 heteroátomos seleccionados independientemente de hasta 2 átomos de O, hasta 2 átomos de S y hasta 4 átomos de N, en donde hasta 3 miembros de anillo de carbono se seleccionan independientemente de C(=O) y C(=S), y los miembros de anillo de átomos de azufre se seleccionan independientemente de S(=O)ᵘ(=NR¹⁴)ᵛ; cada anillo o sistema anular está sustituido opcionalmente con hasta 5 sustituyentes seleccionados independientemente de R³ en miembros de anillo de átomos de carbono y seleccionados de ciano, alquilo C₁₋₆, alquenilo C₂₋₆, alquinilo C₂₋₆, cicloalquilo C₃₋₆, alcoxi C₁₋₆, alcoxialquilo C₂₋₆, alquilcarbonilo C₂₋₆, alcoxicarbonilo C₂₋₆, alquilaminoalquilo C₂₋₆ y dialquilaminoalquilo C₃₋₆ en miembros de anillo de átomos de nitrógeno; o alquilo C₁₋₁₂, alquenilo C₂₋₁₂, alquinilo C₂₋₁₂, cicloalquilo C₃₋₁₂ o cicloalquenilo C₃₋₁₂; cada uno está sustituido opcionalmente con hasta 5 sustituyentes seleccionados independientemente de R³; X es O, NR⁴ o CR¹⁵R¹⁶; R¹ es H, halógeno, alquilo C₁₋₆, haloalquilo C₁₋₆, alquenilo C₂₋₄, alquinilo C₂₋₄, cicloalquilo C₃₋₇, CO₂R⁵, C(O)NR⁶R⁷, ciano, alcoxi C₁₋₆, haloalcoxi C₁₋₆ o alcoxialquilo C₂₋₅; o R¹ es fenilo sustituido opcionalmente con hasta 3 R⁸; o un heterociclo aromático de cinco o seis miembros que contiene nitrógeno sustituido opcionalmente con hasta 3 sustituyentes seleccionados independientemente de R⁹ᵃ en miembros de anillo de átomos de carbono y R⁹ᵇ en miembros de anillo de átomos de nitrógeno; R¹ᵃ es H; o R¹ᵃ y R¹ se toman junto con el átomo de carbono al cual están unidos para formar un anillo de ciclopropilo sustituido opcionalmente con hasta 2 sustituyentes seleccionados independientemente de halógeno y metilo; R² es H, alquenilo C₂₋₃ o alquinilo C₂₋₃; cada R³ se selecciona independientemente de halógeno, ciano, nitro, amino, metilamino, dimetilamino, formilamino, alquilcarbonilamino C₂₋₃, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₃, haloalcoxi C₁₋₃, alquiltio C₁₋₃, haloalquiltio C₁₋₃, alquilsulfinilo C₁₋₃, haloalquilsulfinilo C₁₋₃, alquilsulfonilo C₁₋₃, haloalquilsulfonilo C₁₋₃, alquilsulfoniloxi C₁₋₂, haloalquilsulfoniloxi C₁₋₂, cicloalquilo C₃₋₄, cicloalcoxi C₃₋₇, alquilcicloalquilo C₄₋₆, cicloalquilalquilo C₄₋₆, halocicloalquilo C₃₋₇, alquenilo C₂₋₄, alquinilo C₂₋₄, hidroxi, formilo, alquilcarbonilo C₂₋₃, alquilcarboniloxi C₂₋₃, -SF₅, -SCN, C(=S)NR¹⁹R²⁰, C(=NOR²⁷)R²⁸ o -U-V-T; R⁴ es H, formilo, alquenilo C₂₋₅, alquinilo C₃₋₅, cicloalquilo C₃₋₇, -SO₃⁻M⁺, -S(=O)ₜR¹⁰, -(C=W)R¹¹, NH₂ o OR²¹; o alquilo C₁₋₆ o haloalquilo C₁₋₆; cada uno está sustituido opcionalmente con hasta 2 R¹²; R⁵ es H, alquilo C₁₋₆ o haloalquilo C₁₋₆; R⁶ y R⁷ se seleccionan independientemente de H, alquilo C₁₋₆, haloalquilo C₁₋₆, cicloalquilo C₃₋₇, cicloalquilalquilo C₄₋₈ y alquilcicloalquilo C₄₋₈; o R⁶ y R⁷ se toman junto con el átomo de nitrógeno al cual están conectados para formar un anillo heterocíclico no aromático de cuatro a siete miembros que contiene miembros de anillo, además del átomo de nitrógeno del anillo conector, seleccionados de átomos de carbono y, opcionalmente, hasta un miembro de anillo seleccionado de O, S(O)ₙ y NR¹³; cada R⁸, R⁹ᵃ y R⁹ᵇ se selecciona independientemente de halógeno, alquilo C₁₋₂, haloalquilo C₁₋₂, alcoxi C₁₋₂, haloalcoxi C₁₋₂, ciano, nitro, SCH₃, S(O)CH₃ y S(O)₂CH₃; R¹⁰ es alquilo C₁₋₆ o haloalquilo C₁₋₆; cada R¹¹ es independientemente alquilo C₁₋₆, alcoxi C₁₋₆, alcoxialquilo C₂₋₇, alquilaminoalquilo C₂₋₇, dialquilaminoalquilo C₂₋₈, alquiltio C₁₋₆ o alquiltioalquilo C₂₋₇; cada R¹² es independientemente cicloalquilo C₃₋₇, alcoxi C₁₋₄, haloalcoxi C₁₋₄, alquiltio C₁₋₄, alquilsulfinilo C₁₋₄, alquilsulfonilo C₁₋₄ o ciano; R¹³ es H, alquilo C₁₋₃ o haloalquilo C₂₋₃; cada R¹⁴ es independientemente H, ciano, alquilo C₁₋₃ o haloalquilo C₁₋₃; R¹⁵ es H o alquilo C₁₋₄; R¹⁶ es F, Cl o OR¹⁸; cada R¹⁸ es independientemente H, formilo, cicloalquilo C₃₋₇, -SO₃⁻M⁺ o -(C=W)R¹¹; o alquilo C₁₋₆ o haloalquilo C₁₋₆ cada uno está sustituido opcionalmente con hasta 2 R¹²; cada R¹⁹ y R²⁰ es independientemente H o CH₃; R²¹ es H, formilo, cicloalquilo C₃₋₇, -SO₃⁻M⁺ o -(C=W)R¹¹; o alquilo C₁₋₆ o haloalquilo C₁₋₆; cada uno está sustituido opcionalmente con hasta 2 R¹²; cada U es independientemente O, S(=O)ʷ, NR²² o un enlace directo; cada V es independientemente alquileno C₁₋₆, alquenileno C₂₋₆, alquinileno C₃₋₆, cicloalquileno C₃₋₆ o cicloalquenileno C₃₋₆, en donde hasta 3 átomos de carbono se seleccionan independientemente de C(=O); cada uno está sustituido opcionalmente con hasta 5 sustituyentes seleccionados independientemente de halógeno, ciano, nitro, hidroxi, alquilo C₁₋₆, haloalquilo C₁₋₆, alcoxi C₁₋₆ y haloalcoxi C₁₋₆; cada T es independientemente ciano, NR²³ᵃR²³ᵇ, OR²⁴ o S(=O)ʸR²⁵; cada R²² es independientemente H, alquilo C₁₋₆, haloalquilo C₁₋₆, alquilcarbonilo C₂₋₆, alcoxicarbonilo C₂₋₆, (alquiltio)carbonilo C₂₋₆, alcoxi(tiocarbonilo) C₂₋₆, cicloalquilcarbonilo C₄₋₈, cicloalcoxicarbonilo C₄₋₈, (cicloalquiltio)carbonilo C₄₋₈ o cicloalcoxi(tiocarbonilo) C₄₋₈; cada R²³ᵃ y R²³ᵇ es independCompositions containing the compounds of the formula (1) and methods for controlling plant diseases caused by a fungal pathogen are described; The method comprises applying an effective amount of a compound or a composition of the present. Claim 1: A compound selected from the formula (1), N-oxides and salts thereof, characterized in that Q¹ is an annular ring or system of phenyl or naphthalenyl; each ring or annular system is optionally substituted with up to 5 substituents independently selected from R³; or a fully unsaturated 5- to 6-membered heterocyclic ring or an 8 to 10-membered heteroaromatic bicyclic ring system; Each ring or ring system contains selected ring members of carbon atoms and up to 4 heteroatoms independently selected from up to 2 O atoms, up to 2 S atoms and up to 4 N atoms, where up to 3 carbon ring members are selected independently of C (= O) and C (= S) and the ring members of sulfur atoms are independently selected from S (= O) ᵘ (= NR¹⁴) ᵛ; Each ring or annular system is optionally substituted with up to 5 substituents independently selected from R³ in ring members of carbon atoms and selected from cyano, C₁₋₆ alkyl, C₂₋₆ alkenyl, C₂₋₆ alkynyl, C₃₋₆ cycloalkyl, alkoxy C₁₋₆, C₂₋₆ alkoxyalkyl, C₂₋₆ alkylcarbonyl, C₂₋₆ alkoxycarbonyl, C₂₋₆ alkylaminoalkyl and C₃₋₆ dialkylaminoalkyl in ring members of nitrogen atoms; Q² is a ring or ring system of phenyl or naphthalenyl; each ring or annular system is optionally substituted with up to 5 substituents independently selected from R³; or a saturated, partially unsaturated or totally unsaturated 4, 5 or 6 membered heterocyclic ring or an 8 to 10 membered heteroaromatic bicyclic ring system; Each ring or ring system contains selected ring members of carbon atoms and up to 4 heteroatoms independently selected from up to 2 O atoms, up to 2 S atoms and up to 4 N atoms, where up to 3 carbon ring members are selected independently of C (= O) and C (= S), and the ring members of sulfur atoms are independently selected from S (= O) ᵘ (= NR¹⁴) ᵛ; Each ring or annular system is optionally substituted with up to 5 substituents independently selected from R³ in ring members of carbon atoms and selected from cyano, C₁₋₆ alkyl, C₂₋₆ alkenyl, C₂₋₆ alkynyl, C₃₋₆ cycloalkyl, alkoxy C₁₋₆, C₂₋₆ alkoxyalkyl, C₂₋₆ alkylcarbonyl, C₂₋₆ alkoxycarbonyl, C₂₋₆ alkylaminoalkyl and C₃₋₆ dialkylaminoalkyl in ring members of nitrogen atoms; or C₁₋₁₂ alkyl, C₂₋₁₂ alkenyl, C₂₋₁₂ alkynyl, C₃₋₁₂ cycloalkyl or C₃₋₁₂ cycloalkenyl; each is optionally substituted with up to 5 substituents independently selected from R³; X is O, NR⁴ or CR¹⁵R¹⁶; R¹ is H, halogen, C₁₋₆ alkyl, C₁₋₆ haloalkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, C₃₋₇ cycloalkyl, CO₂R⁵, C (O) NR⁶R⁷, cyano, C₁₋₆ alkoxy, C₁₋₆ haloalkoxy or C₂₋₅ alkoxyalkyl; or R¹ is phenyl optionally substituted with up to 3 R⁸; or a five or six membered aromatic heterocycle containing nitrogen optionally substituted with up to 3 substituents independently selected from R⁹ᵃ in ring members of carbon atoms and R⁹ᵇ in ring members of nitrogen atoms; R¹ᵃ is H; or R¹ᵃ and R¹ are taken together with the carbon atom to which they are attached to form a cyclopropyl ring optionally substituted with up to 2 substituents independently selected from halogen and methyl; R² is H, C₂₋₃ alkenyl or C₂₋₃ alkynyl; each R³ is independently selected from halogen, cyano, nitro, amino, methylamino, dimethylamino, formylamino, C₂₋₃ alkylcarbonylamino, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₃ alkoxy, C₁₋₃ haloalkoxy, C₁₋₃ alkylthio, C₁₋₃ haloalkylthio, C₁₋₃ alkylsulfinyl, C₁₋₃ haloalkylsulfinyl, C₁₋₃ alkylsulfonyl, C₁₋₃ haloalkylsulfonyl, C₁₋₂ alkylsulfonyloxy, C₁₋₂ haloalkylsulfonyloxy, C ciclo cycloalkoxy, C₄₋₆ alkylcycloalkyl, C₄₋₆ cycloalkylalkyl, C₃₋₇ halocycloalkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, hydroxy, formyl, C₂₋₃ alkylcarbonyl, C₂₋₃ alkylcarbonyloxy, -SF₅, -SCN, C (= S) NR¹⁹R²⁰, C (= NOR²⁷) R²⁸ or -UVT; R⁴ is H, formyl, C₂₋₅ alkenyl, C₃₋₅ alkynyl, C₃₋₇ cycloalkyl, -SO₃⁻M⁺, -S (= O) ₜR¹⁰, - (C = W) R¹¹, NH₂ or OR²¹; or C₁₋₆ alkyl or C₁₋₆ haloalkyl; each is optionally substituted with up to 2 R¹²; R⁵ is H, C₁₋₆ alkyl or C₁₋₆ haloalkyl; R⁶ and R⁷ are independently selected from H, C₁₋₆ alkyl, C₁₋₆ haloalkyl, C₃₋₇ cycloalkyl, C₄₋₈ cycloalkylalkyl and C₄₋₈ alkylcycloalkyl; or R⁶ and R⁷ are taken together with the nitrogen atom to which they are connected to form a four to seven membered non-aromatic heterocyclic ring containing ring members, in addition to the nitrogen atom of the linker ring, selected from carbon atoms and, optionally, up to a ring member selected from O, S (O) ₙ and NR¹³; each R⁸, R⁹ᵃ and R⁹ᵇ is independently selected from halogen, C₁₋₂ alkyl, C₁₋₂ haloalkyl, C₁₋₂ alkoxy, C₁₋₂ haloalkoxy, cyano, nitro, SCH₃, S (O) CH₃ and S (O) ₂CH₃; R¹⁰ is C₁₋₆ alkyl or C₁₋₆ haloalkyl; each R¹¹ is independently C₁₋₆ alkyl, C₁₋₆ alkoxy, C₂₋₇ alkoxyalkyl, C₂₋₇ alkylaminoalkyl, C₂₋₈ dialkylaminoalkyl, C₁₋₆ alkylthio or C₂₋₇ alkylthioalkyl; each R¹² is independently C₃₋₇ cycloalkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, C₁₋₄ alkylthio, C₁₋₄ alkylsulfinyl, C₁₋₄ alkylsulfonyl or cyano; R¹³ is H, C₁₋₃ alkyl or C₂₋₃ haloalkyl; each R¹⁴ is independently H, cyano, C₁₋₃ alkyl or C₁₋₃ haloalkyl; R¹⁵ is H or C₁₋₄ alkyl; R¹⁶ is F, Cl or OR¹⁸; each R¹⁸ is independently H, formyl, C₃₋₇ cycloalkyl, -SO₃⁻M⁺ or - (C = W) R¹¹; or C₁₋₆ alkyl or C₁₋₆ haloalkyl each is optionally substituted with up to 2 R¹²; each R¹⁹ and R²⁰ is independently H or CH₃; R²¹ is H, formyl, C₃₋₇ cycloalkyl, -SO₃⁻M⁺ or - (C = W) R¹¹; or C₁₋₆ alkyl or C₁₋₆ haloalkyl; each is optionally substituted with up to 2 R¹²; each U is independently O, S (= O) ʷ, NR²² or a direct link; each V is independently C₁₋₆ alkylene, C₂₋₆ alkenylene, C₃₋₆ alkynylene, C₃₋₆ cycloalkylene or C₃₋₆ cycloalkenylene, wherein up to 3 carbon atoms are independently selected from C (= O); each is optionally substituted with up to 5 substituents independently selected from halogen, cyano, nitro, hydroxy, C₁₋₆ alkyl, C₁₋₆ haloalkyl, C₁₋₆ alkoxy and C₁₋₆ haloalkoxy; each T is independently cyano, NR²³ᵃR²³ᵇ, OR²⁴ or S (= O) ʸR²⁵; each R²² is independently H, C alquilo alkyl, C₁₋₆ haloalkyl, C₂₋₆ alkylcarbonyl, C₂₋₆ alkoxycarbonyl, C₂₋₆ (alkylthio) carbonyl, C₂₋₆ alkoxy (thiocarbonyl), C₄₋₈ cycloalkylcarbonyl, C₄₋ cycloalkoxycarbonyl ₈, (C-cycloalkylthio) carbonyl or C₄₋₈-cycloalkoxy (thiocarbonyl); each R²³ᵃ and R²³ᵇ is independent

ARP130100510A 2012-02-20 2013-02-19 FUNGICIDE PIRAZOLS AR090098A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261600939P 2012-02-20 2012-02-20

Publications (1)

Publication Number Publication Date
AR090098A1 true AR090098A1 (en) 2014-10-22

Family

ID=47790526

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130100510A AR090098A1 (en) 2012-02-20 2013-02-19 FUNGICIDE PIRAZOLS

Country Status (2)

Country Link
AR (1) AR090098A1 (en)
WO (1) WO2013126283A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI504350B (en) 2010-09-01 2015-10-21 Du Pont Fungicidal pyrazoles and their mixtures
US20170037014A1 (en) 2014-05-06 2017-02-09 E. I. Du Pont De Nemours And Company Fungicidal pyrazoles
WO2016012424A1 (en) 2014-07-24 2016-01-28 Bayer Cropscience Aktiengesellschaft Fungicidal pyrazole derivatives
WO2016026830A1 (en) * 2014-08-21 2016-02-25 Bayer Cropscience Aktiengesellschaft Novel fungicidal pyrazole derivatives
CN105777640B (en) * 2014-12-19 2020-01-07 沈阳中化农药化工研发有限公司 Pyrazole cyclohexanediol ether compound and application thereof
CA2978066A1 (en) 2015-03-19 2016-09-22 E I Du Pont De Nemours And Company Fungicidal pyrazoles
WO2017087905A1 (en) 2015-11-20 2017-05-26 Denali Therapeutics Inc. Compound, compositions, and methods
US11028080B2 (en) 2016-03-11 2021-06-08 Denali Therapeutics Inc. Substituted pyrimidines as LRKK2 inhibitors
KR20230107407A (en) 2016-06-16 2023-07-14 데날리 테라퓨틱스 인크. Pyrimidin-2-ylamino-1h-pyrazols as lrrk2 inhibitors for use in the treatment of neurodegenerative disorders
WO2018052838A1 (en) 2016-09-16 2018-03-22 E. I. Du Pont De Nemours And Company Fungicidal pyrazoles
TW202400547A (en) 2018-09-06 2024-01-01 美商富曼西公司 Fungicidal nitroanilino substituted pyrazoles
TW202200012A (en) 2020-03-11 2022-01-01 美商富曼西公司 Fungicidal mixtures
WO2024046890A1 (en) * 2022-09-01 2024-03-07 Syngenta Crop Protection Ag Herbicidal pyrazole compounds

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891855A (en) 1954-08-16 1959-06-23 Geigy Ag J R Compositions and methods for influencing the growth of plants
US3235361A (en) 1962-10-29 1966-02-15 Du Pont Method for the control of undesirable vegetation
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US3309192A (en) 1964-12-02 1967-03-14 Du Pont Method of controlling seedling weed grasses
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
GB2054555A (en) * 1979-07-27 1981-02-18 Abbott Lab Pyrazolyl amino imidazolines
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
DE3246493A1 (en) 1982-12-16 1984-06-20 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING WATER-DISPERSIBLE GRANULES
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
DK0777964T3 (en) 1989-08-30 2002-03-11 Kynoch Agrochemicals Proprieta Process for preparing a dosing system
US5372989A (en) 1990-03-12 1994-12-13 E. I. Du Pont De Nemours And Company Water-dispersible or water-soluble pesticide grandules from heat-activated binders
DE69122201T2 (en) 1990-10-11 1997-02-06 Sumitomo Chemical Co Pesticides composition
EP0627423A4 (en) 1992-01-22 1995-02-15 Nissan Chemical Ind Ltd Substituted pyrazole derivative and agrohorticultural bactericide.
DE19619112A1 (en) 1996-05-11 1997-11-13 Wella Ag Oxidative hair dye containing 4-amino-5-hydroxy-pyrazole or derivative
TW200724033A (en) 2001-09-21 2007-07-01 Du Pont Anthranilamide arthropodicide treatment
GB0227555D0 (en) 2002-11-26 2002-12-31 Syngenta Ltd Fungicides
GB0312863D0 (en) 2003-06-04 2003-07-09 Syngenta Ltd Fungicides
PL1651612T3 (en) 2003-07-22 2012-09-28 Astex Therapeutics Ltd 3,4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinases (cdk) and glycogen synthase kinase-3 (gsk-3) modulators
GB0426372D0 (en) 2004-12-01 2005-01-05 Syngenta Ltd Fungicides
GB0426373D0 (en) 2004-12-01 2005-01-05 Syngenta Ltd Fungicides
US8404718B2 (en) 2005-01-21 2013-03-26 Astex Therapeutics Limited Combinations of pyrazole kinase inhibitors
MX2008015648A (en) 2006-06-21 2009-01-09 Du Pont Pyrazinones as cellular proliferation inhibitors.
KR20150090281A (en) 2006-12-29 2015-08-05 아비에 도이치란트 게엠베하 운트 콤파니 카게 Carboxamide compounds and their use as calpain inhibitors
JPWO2008093639A1 (en) * 2007-01-29 2010-05-20 武田薬品工業株式会社 Pyrazole compounds
GB0704906D0 (en) 2007-03-14 2007-04-25 Syngenta Participations Ag Fungicides
GB0717258D0 (en) 2007-09-05 2007-10-17 Syngenta Participations Ag Novel fungicides
GB0717260D0 (en) 2007-09-05 2007-10-17 Syngenta Participations Ag Novel fungicides
GB0800407D0 (en) 2008-01-10 2008-02-20 Syngenta Participations Ag Fungicides
JP5696037B2 (en) 2008-05-01 2015-04-08 ヴァイティー ファーマシューティカルズ，インコーポレイテッド Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1
TW201010977A (en) 2008-08-12 2010-03-16 Takeda Pharmaceutical Amide compound
WO2010093885A1 (en) 2009-02-12 2010-08-19 Glaxosmithkline Llc Inhibitors of akt activity
AR075713A1 (en) 2009-03-03 2011-04-20 Du Pont FUNGICIDE PIRAZOLS
AR079545A1 (en) 2009-12-21 2012-02-01 Bayer Cropscience Ag TIENILPIRI (MI) DINILAZOL
TWI504350B (en) * 2010-09-01 2015-10-21 Du Pont Fungicidal pyrazoles and their mixtures

Also Published As

Publication number Publication date
WO2013126283A1 (en) 2013-08-29

Similar Documents

Publication Publication Date Title
AR090098A1 (en) FUNGICIDE PIRAZOLS
AR116978A1 (en) SUBSTITUTE TOLYL FUNGICIDES
AR104808A1 (en) CYCLIC AMIDAS REPLACED AS HERBICIDES
AR094840A1 (en) FUNGICIDE PIRAZOLS
AR104618A1 (en) HERBICIDES DERIVED FROM BICYCLIC COMPOUNDS REPLACED WITH ARILO
AR104214A1 (en) CYCLIC AMIDAS REPLACED AS HERBICIDES
AR117163A2 (en) PARASITICIDE COMPOSITIONS INCLUDING AN ACTIVE ISOXAZOLINE AGENT, ITS METHODS AND USES
AR102939A1 (en) 3-OXO-3- (ARILAMINO) PROPANOATS, PROCESS TO PREPARE THEM, AND ITS USE TO PREPARE PIRROLIDINONES
AR104420A1 (en) BUTIROLACTONES AS HERBICIDES
AR101102A1 (en) PIPERIDINONE HERBICIDES
AR099122A1 (en) PIRIMIDINYLOXI BENZENE DERIVATIVES AS HERBICIDES
AR109346A1 (en) DERIVATIVES OF BICYCLIC HETEROCICLES CONDENSED AS PESTICIDES
AR105544A1 (en) CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES
AR103965A1 (en) DERIVATIVES OF PYRIMIDINYLOXI PIRIDINE REPLACED AS HERBICIDES
AR104714A1 (en) DEPSIPEPTIDE COMPOUNDS AS ANTIHELMINICS
AR104915A1 (en) DERIVATIVES OF 2- (PHENYLOXY OR PHENYLTIUM) PYRIMIDINE AS HERBICIDES
AR107397A1 (en) DERIVATIVES OF BICYCLIC HETEROCICLES CONDENSED AS PESTICIDES
AR106100A1 (en) BICYCLIC COMPOUNDS AS ATX / CA DUAL INHIBITORS
AR075713A1 (en) FUNGICIDE PIRAZOLS
AR096023A1 (en) FUNGICIDE AMIDAS
AR091225A1 (en) FUNGUITED HETEROCICLICAL COMPOUNDS
AR116311A1 (en) ISOXAZOLINE COMPOUNDS TO CONTROL INVERTEBRATE PESTS
AR080684A1 (en) ARIL- AND HETARILSULFONAMIDAS AS ACTIVE SUBSTANCES AGAINST AN ABIOTIC PLANTS STRESS
AR082869A1 (en) FUNGICIDE PIRAZOLS
AR098492A1 (en) PURINA DERIVATIVES

Legal Events

Date Code Title Description
FB Suspension of granting procedure