AR088704A1 - VAGINAL RING INCLUDING DHEA OR DHEA SULFATE AND OPTIONALLY A MODULATING AGENT FOR THE RELEASE OF THE ACTIVE PRINCIPLE, USEFUL TO INCREASE OVARIC RESERVE IN WOMEN AND TO RELIEF SYMPTOMS ASSOCIATED WITH MENOPAUSE - Google Patents

VAGINAL RING INCLUDING DHEA OR DHEA SULFATE AND OPTIONALLY A MODULATING AGENT FOR THE RELEASE OF THE ACTIVE PRINCIPLE, USEFUL TO INCREASE OVARIC RESERVE IN WOMEN AND TO RELIEF SYMPTOMS ASSOCIATED WITH MENOPAUSE

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Publication number
AR088704A1
AR088704A1 ARP120104974A ARP120104974A AR088704A1 AR 088704 A1 AR088704 A1 AR 088704A1 AR P120104974 A ARP120104974 A AR P120104974A AR P120104974 A ARP120104974 A AR P120104974A AR 088704 A1 AR088704 A1 AR 088704A1
Authority
AR
Argentina
Prior art keywords
dhea
women
release
modulating agent
vaginal ring
Prior art date
Application number
ARP120104974A
Other languages
Spanish (es)
Inventor
Ariel Fuentes Garcia Frans
Chen Shu
Del Carmen Chen-Beltran Apablaza Marianela
Original Assignee
Univ Chile
Andromaco Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CL2011003352A external-priority patent/CL2011003352A1/en
Priority claimed from PCT/IB2011/056023 external-priority patent/WO2013098592A1/en
Application filed by Univ Chile, Andromaco Lab filed Critical Univ Chile
Publication of AR088704A1 publication Critical patent/AR088704A1/en

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Anillo vaginal de liberación sostenida que comprende como principio activo dehidroepiandrosterona (DHEA), dehidroepiandrosterona sulfato (DHEA-S) o una sal farmacéuticamente aceptable de éstos y, opcionalmente, un agente modulador de la liberación del principio activo, donde la cantidad del ingrediente activo se encuentra entre 1% a 32% en peso, en relación al peso total de la formulación y el agente modulador se selecciona entre: polivinilpirrolidona K-30, lactosa, celulosa microcristalina y lauril sulfato de sodio. El anillo vaginal de la presente es útil para aumentar la reserva ovárica en mujeres, para ser utilizado como medicamento en programas de reproducción asistida y para aliviar síntomas asociados a la menopausia, tales como síntomas de la atrofia vulvovaginal y disfunción sexual en mujeres post menopáusicas.Sustained-release vaginal ring comprising as active ingredient dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S) or a pharmaceutically acceptable salt thereof and, optionally, an active ingredient release modulating agent, where the amount of the active ingredient is It is between 1% and 32% by weight, in relation to the total weight of the formulation and the modulating agent is selected from: polyvinylpyrrolidone K-30, lactose, microcrystalline cellulose and sodium lauryl sulfate. The vaginal ring of the present is useful to increase ovarian reserve in women, to be used as a medicine in assisted reproduction programs and to relieve symptoms associated with menopause, such as symptoms of vulvovaginal atrophy and sexual dysfunction in post menopausal women.

ARP120104974A 2011-12-29 2012-12-26 VAGINAL RING INCLUDING DHEA OR DHEA SULFATE AND OPTIONALLY A MODULATING AGENT FOR THE RELEASE OF THE ACTIVE PRINCIPLE, USEFUL TO INCREASE OVARIC RESERVE IN WOMEN AND TO RELIEF SYMPTOMS ASSOCIATED WITH MENOPAUSE AR088704A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CL2011003352A CL2011003352A1 (en) 2011-12-29 2011-12-29 Sustained-release vaginal ring comprising as active agent dehydroepiandrosterone, dehydroepiandrosterone sulfate or a salt thereof, and optionally a release agent modulating the active agent; and its use to increase ovarian reserve in women and to treat symptoms associated with menopause.
PCT/IB2011/056023 WO2013098592A1 (en) 2011-12-29 2011-12-29 Vaginal ring which includes dhea or dhea sulphate and optionally an agent for modulating the release of the active principle, which can be used to increase the ovarian reserve in women and to relieve symptoms associated with menopause

Publications (1)

Publication Number Publication Date
AR088704A1 true AR088704A1 (en) 2014-07-02

Family

ID=51421739

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120104974A AR088704A1 (en) 2011-12-29 2012-12-26 VAGINAL RING INCLUDING DHEA OR DHEA SULFATE AND OPTIONALLY A MODULATING AGENT FOR THE RELEASE OF THE ACTIVE PRINCIPLE, USEFUL TO INCREASE OVARIC RESERVE IN WOMEN AND TO RELIEF SYMPTOMS ASSOCIATED WITH MENOPAUSE

Country Status (1)

Country Link
AR (1) AR088704A1 (en)

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