AR086505A1 - A CO-PROCESSED EXCIPIENT, OBTAINED BY DRYING ATOMIZATION, USED AS A PHARMACEUTICAL EXCIPIENT OR FOOD ADDITIVE - Google Patents
A CO-PROCESSED EXCIPIENT, OBTAINED BY DRYING ATOMIZATION, USED AS A PHARMACEUTICAL EXCIPIENT OR FOOD ADDITIVEInfo
- Publication number
- AR086505A1 AR086505A1 ARP120101793A AR086505A1 AR 086505 A1 AR086505 A1 AR 086505A1 AR P120101793 A ARP120101793 A AR P120101793A AR 086505 A1 AR086505 A1 AR 086505A1
- Authority
- AR
- Argentina
- Prior art keywords
- excipient
- spheres
- food additive
- processed
- drying atomization
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
Abstract
Un excipiente co-procesado que comprende partículas constituidas por una dispersión sólida de manitol y polivinilpirrolidona (PVP) en una relación porcentual de entre 75:25 y 95:5, en donde dichas partículas se encuentran en forma de esferas o formando aglomerados de esferas de superficie lisa y uniforme, y en donde dichas esferas o dichos aglomerados de esferas poseen un tamaño expresado como mediana en masa en el rango de entre 1 mm y 60 mm, presentando una distribución de tamaño tipo unimodal con baja desviación relativa.A co-processed excipient comprising particles consisting of a solid dispersion of mannitol and polyvinylpyrrolidone (PVP) in a percentage ratio between 75:25 and 95: 5, wherein said particles are in the form of spheres or forming agglomerates of spheres of smooth and uniform surface, and wherein said spheres or said agglomerates of spheres have a size expressed as median in mass in the range of 1 mm to 60 mm, presenting a unimodal size distribution with low relative deviation.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP120101793 AR086505A1 (en) | 2012-05-21 | 2012-05-21 | A CO-PROCESSED EXCIPIENT, OBTAINED BY DRYING ATOMIZATION, USED AS A PHARMACEUTICAL EXCIPIENT OR FOOD ADDITIVE |
PCT/IB2013/054188 WO2013175405A1 (en) | 2012-05-21 | 2013-05-21 | Co—processed excipient, obtained by spray—drying, usable as a pharmaceutical excipient or food additive |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP120101793 AR086505A1 (en) | 2012-05-21 | 2012-05-21 | A CO-PROCESSED EXCIPIENT, OBTAINED BY DRYING ATOMIZATION, USED AS A PHARMACEUTICAL EXCIPIENT OR FOOD ADDITIVE |
Publications (1)
Publication Number | Publication Date |
---|---|
AR086505A1 true AR086505A1 (en) | 2013-12-18 |
Family
ID=48783301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120101793 AR086505A1 (en) | 2012-05-21 | 2012-05-21 | A CO-PROCESSED EXCIPIENT, OBTAINED BY DRYING ATOMIZATION, USED AS A PHARMACEUTICAL EXCIPIENT OR FOOD ADDITIVE |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR086505A1 (en) |
WO (1) | WO2013175405A1 (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3145146A (en) | 1961-10-31 | 1964-08-18 | Warner Lambert Pharmaceutical | Modified mannitol for pharmaceutical tablets |
EP0487774B1 (en) | 1990-11-29 | 1994-10-26 | Wei Ming Pharmaceutical Mfg. Co. Ltd. | A direct tabletting auxiliary |
US5576014A (en) | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
AU2002302814A1 (en) * | 2001-06-08 | 2002-12-23 | Powderject Vaccines, Inc. | Spray freeze-dried compositions |
DE10161402A1 (en) | 2001-12-13 | 2003-06-18 | Merck Patent Gmbh | Process for the production of directly tablettable beta-mannitol |
-
2012
- 2012-05-21 AR ARP120101793 patent/AR086505A1/en not_active Application Discontinuation
-
2013
- 2013-05-21 WO PCT/IB2013/054188 patent/WO2013175405A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2013175405A1 (en) | 2013-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |