AR083721A1 - CONSTANT DOMAIN IgE PEPTIDE VACCINE (CH) - Google Patents

CONSTANT DOMAIN IgE PEPTIDE VACCINE (CH)

Info

Publication number
AR083721A1
AR083721A1 ARP110101955A AR083721A1 AR 083721 A1 AR083721 A1 AR 083721A1 AR P110101955 A ARP110101955 A AR P110101955A AR 083721 A1 AR083721 A1 AR 083721A1
Authority
AR
Argentina
Prior art keywords
immunogenic
ige peptide
compositions
constant domain
peptide
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Brian Robert Champion
David Robert Stead
Paul Andrew Wright
Original Assignee
Pfizer Vaccines Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Vaccines Llc filed Critical Pfizer Vaccines Llc
Priority to ARP110101955 priority Critical patent/AR083721A1/en
Publication of AR083721A1 publication Critical patent/AR083721A1/en

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se provee también composiciones que comprenden los inmunógenos y procedimientos para la prevención, tratamiento o alivio de trastornos mediados por IgE. Además procedimientos para la producción de estos medicamentos, composiciones inmunogénicas y composiciones farmacéuticas de los mismos y su uso en medicina.Reivindicación 1: Un inmunógeno caracterizado porque comprende al menos un péptido de IgE antigénico unido a un vehículo inmunogénico, en el que: dicho péptido de lgE antigénico consiste en una secuencia de aminoácidos seleccionada del grupo que consiste en las SEC ID Nº 1 a 430; dicho vehículo inmunogénico se selecciona del grupo que consiste en DT (toxina Diftérica), TT (toxoide tetánico) o fragmento C de TT, PD (proteína D de Haemophilus influenzae), CRM197, CRM176, CRM228, CRM45, CRM9, CRM102, CRM103 y CRM107 y en el que dicho péptido de IgE antigénico está entrecruzado químicamente con dicho vehículo inmunogénico.Compositions comprising immunogens and procedures for the prevention, treatment or relief of IgE-mediated disorders are also provided. In addition, procedures for the production of these medicaments, immunogenic compositions and pharmaceutical compositions thereof and their use in medicine. Claim 1: An immunogen characterized in that it comprises at least one antigenic IgE peptide bound to an immunogenic vehicle, wherein: said peptide of antigenic IgE consists of an amino acid sequence selected from the group consisting of SEQ ID NOS 1 to 430; said immunogenic vehicle is selected from the group consisting of DT (Dimeric toxin), TT (tetanus toxoid) or C fragment of TT, PD (Haemophilus influenzae protein D), CRM197, CRM176, CRM228, CRM45, CRM9, CRM102, CRM103 and CRM107 and wherein said antigenic IgE peptide is chemically crosslinked with said immunogenic vehicle.

ARP110101955 2011-06-06 2011-06-06 CONSTANT DOMAIN IgE PEPTIDE VACCINE (CH) AR083721A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP110101955 AR083721A1 (en) 2011-06-06 2011-06-06 CONSTANT DOMAIN IgE PEPTIDE VACCINE (CH)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP110101955 AR083721A1 (en) 2011-06-06 2011-06-06 CONSTANT DOMAIN IgE PEPTIDE VACCINE (CH)

Publications (1)

Publication Number Publication Date
AR083721A1 true AR083721A1 (en) 2013-03-20

Family

ID=48486020

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110101955 AR083721A1 (en) 2011-06-06 2011-06-06 CONSTANT DOMAIN IgE PEPTIDE VACCINE (CH)

Country Status (1)

Country Link
AR (1) AR083721A1 (en)

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