AR080285A1 - FLUIDICA DEVICE FOR MOLECULES ELECTROPHORESIS. - Google Patents
FLUIDICA DEVICE FOR MOLECULES ELECTROPHORESIS.Info
- Publication number
- AR080285A1 AR080285A1 ARP100104628A ARP100104628A AR080285A1 AR 080285 A1 AR080285 A1 AR 080285A1 AR P100104628 A ARP100104628 A AR P100104628A AR P100104628 A ARP100104628 A AR P100104628A AR 080285 A1 AR080285 A1 AR 080285A1
- Authority
- AR
- Argentina
- Prior art keywords
- molecules
- channel
- electrode
- electrodes
- closed geometry
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/4473—Arrangements for investigating the separated zones, e.g. localising zones by electric means
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
La solicitud se refiere a un dispositivo de fluídica para realizar electroforesis de moléculas. El dispositivo de la solicitud tiene como característica novedosa canales de geometría cerrada (por ejemplo circular) y potenciales variables en el tiempo. La migracion de las moléculas está contenida en un canal de geometría cerrada, por él cual pueden circular una y otra vez, separándose así las moléculas en una distancia de migracion amplia. El dispositivo de la solicitud presenta un sistema de inyeccion que es un canal secundario que intersecta al canal principal de geometría cerrada. El dispositivo incorpora un arreglo de electrodos a lo largo de este canal principal (3 o más) y dichos electrodos están conectados a una fuente de tension variable con multiples salidas que regula el valor del potencial eléctrico en cada electrodo, y la frecuencia con que el mismo varía de electrodo a electrodo. Se logra así generar un arreglo periodico de potenciales a lo largo del canal que establecen el flujo de la muestra optimizando el proceso de separacion. También pueden anadirse electrodos que sirvan para la deteccion de las moléculas a través de la medicion de cambios en la resistividad eléctrica, corriente o voltaje, o bien utilizar otros elementos y otros métodos conocidos, como ser: espectroscopia de fluorescencia, sistemas nanosensores basados en nanotubos, sistema de deteccion de pasaje de las moléculas a través de nano poros puestos en puntos específicos del canal.The application refers to a fluidic device for electrophoresis of molecules. The device of the application has as a novel feature closed geometry channels (for example circular) and time-varying potentials. The migration of the molecules is contained in a closed geometry channel, through which they can circulate again and again, thus separating the molecules over a wide migration distance. The request device has an injection system that is a secondary channel that intersects the main closed geometry channel. The device incorporates an array of electrodes along this main channel (3 or more) and said electrodes are connected to a variable voltage source with multiple outputs that regulates the value of the electrical potential in each electrode, and the frequency with which the It varies from electrode to electrode. It is thus possible to generate a periodic arrangement of potentials along the channel that establish the flow of the sample optimizing the separation process. Electrodes can also be added that serve to detect molecules through the measurement of changes in electrical resistivity, current or voltage, or use other elements and other known methods, such as: fluorescence spectroscopy, nanotube-based nanosensor systems , passage detection system of molecules through nano pores placed at specific points of the channel.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ARP100104628A AR080285A1 (en) | 2010-12-14 | 2010-12-14 | FLUIDICA DEVICE FOR MOLECULES ELECTROPHORESIS. |
| US13/316,985 US20120181178A1 (en) | 2010-12-14 | 2011-12-12 | Fluidic device for electrophoresis of molecules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ARP100104628A AR080285A1 (en) | 2010-12-14 | 2010-12-14 | FLUIDICA DEVICE FOR MOLECULES ELECTROPHORESIS. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR080285A1 true AR080285A1 (en) | 2012-03-28 |
Family
ID=46003364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100104628A AR080285A1 (en) | 2010-12-14 | 2010-12-14 | FLUIDICA DEVICE FOR MOLECULES ELECTROPHORESIS. |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US20120181178A1 (en) |
| AR (1) | AR080285A1 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0544969B1 (en) * | 1991-12-06 | 1997-03-05 | Ciba-Geigy Ag | Apparatus and method for electrophoretic separation |
| US5800690A (en) * | 1996-07-03 | 1998-09-01 | Caliper Technologies Corporation | Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces |
-
2010
- 2010-12-14 AR ARP100104628A patent/AR080285A1/en unknown
-
2011
- 2011-12-12 US US13/316,985 patent/US20120181178A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120181178A1 (en) | 2012-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |