AR079266A1 - DERIVATIVES OF AZABICICLO [3.2.0] HEPT-6ILO, SAME PREPARATION PROCEDURE, SYNTHESIS INTERMEDIARIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE OF THEM FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES, SUCH AS. - Google Patents

DERIVATIVES OF AZABICICLO [3.2.0] HEPT-6ILO, SAME PREPARATION PROCEDURE, SYNTHESIS INTERMEDIARIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE OF THEM FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES, SUCH AS.

Info

Publication number
AR079266A1
AR079266A1 ARP100104485A ARP100104485A AR079266A1 AR 079266 A1 AR079266 A1 AR 079266A1 AR P100104485 A ARP100104485 A AR P100104485A AR P100104485 A ARP100104485 A AR P100104485A AR 079266 A1 AR079266 A1 AR 079266A1
Authority
AR
Argentina
Prior art keywords
6ilo
azabiciclo
hept
derivatives
treatment
Prior art date
Application number
ARP100104485A
Other languages
Spanish (es)
Inventor
Pierre Lestage
Patrick Casara
Anne-Marie Chollet
Fany Panayi
Alain Dhainaut
Jean-Michel Henlin
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of AR079266A1 publication Critical patent/AR079266A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/12—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reivindicacion 1: Compuestos de formula (1) en la que ALK representa una cadena alquileno, W representa un grupo -N(R')-C(=O)R o -C(=O)-N(R')R en el que R y R' representan, independientemente el uno del otro, un átomo de hidrogeno o un grupo alquilo C1-6 lineal o ramificado sustituido opcionalmente con uno o varios grupos elegidos entre halogeno, hidroxi y alcoxi, entendiéndose que el término alquileno designa un radical bivalente, lineal o ramificado, que contiene de 2 a 6 átomos de carbono, el término alcoxi designa un grupo alquil-oxi cuya cadena alquilo, lineal o ramificada, contiene de 1 a 6 átomos de carbono, sus enantiomeros y diastereoisomeros, así como sus sales de adicion a un ácido o a una base farmacéuticamente aceptable.Claim 1: Compounds of formula (1) wherein ALK represents an alkylene chain, W represents a group -N (R ') - C (= O) R or -C (= O) -N (R') R in which R and R 'represent, independently of each other, a hydrogen atom or a linear or branched C1-6 alkyl group optionally substituted with one or more groups selected from halogen, hydroxy and alkoxy, it being understood that the term alkylene designates a bivalent radical, linear or branched, containing 2 to 6 carbon atoms, the term "alkoxy" refers to an alkyl-oxy group whose alkyl chain, linear or branched, contains 1 to 6 carbon atoms, their enantiomers and diastereoisomers, as well as its salts of addition to an acid or a pharmaceutically acceptable base.

ARP100104485A 2009-12-09 2010-12-06 DERIVATIVES OF AZABICICLO [3.2.0] HEPT-6ILO, SAME PREPARATION PROCEDURE, SYNTHESIS INTERMEDIARIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE OF THEM FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES, SUCH AS. AR079266A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0905954A FR2953513B1 (en) 2009-12-09 2009-12-09 NOVEL AZABICYCLO [3.2.0] HEPT-6-YL DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
AR079266A1 true AR079266A1 (en) 2012-01-04

Family

ID=42123039

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100104485A AR079266A1 (en) 2009-12-09 2010-12-06 DERIVATIVES OF AZABICICLO [3.2.0] HEPT-6ILO, SAME PREPARATION PROCEDURE, SYNTHESIS INTERMEDIARIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE OF THEM FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES, SUCH AS.

Country Status (5)

Country Link
AR (1) AR079266A1 (en)
FR (1) FR2953513B1 (en)
TW (1) TW201144279A (en)
UY (1) UY33074A (en)
WO (1) WO2011070252A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866647B1 (en) * 2004-02-20 2006-10-27 Servier Lab NOVEL AZABICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
WO2011070252A1 (en) 2011-06-16
TW201144279A (en) 2011-12-16
FR2953513A1 (en) 2011-06-10
FR2953513B1 (en) 2011-12-23
UY33074A (en) 2011-04-29

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