AR076555A1 - GLICAN ANTIGEN. USE. ANTIBODY. VACCINE. METHOD FOR MANUFACTURING VACCINE - Google Patents
GLICAN ANTIGEN. USE. ANTIBODY. VACCINE. METHOD FOR MANUFACTURING VACCINEInfo
- Publication number
- AR076555A1 AR076555A1 ARP100101582A ARP100101582A AR076555A1 AR 076555 A1 AR076555 A1 AR 076555A1 AR P100101582 A ARP100101582 A AR P100101582A AR P100101582 A ARP100101582 A AR P100101582A AR 076555 A1 AR076555 A1 AR 076555A1
- Authority
- AR
- Argentina
- Prior art keywords
- antigen
- vaccine
- antibody
- ldnf
- gal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0003—Invertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Abstract
La presente solicitud se refiere al campo de la inmunología parasitaria veterinaria. En forma más específica, la solicitud se refiere a una estructura de carbohidratos util para el tratamiento inmunoprotector y para la prevencion o reduccion de las infecciones causadas por los nematodos parasíticos en los rumiantes. Particularmente, la solicitud se refiere a un antígeno que comprende la estructura de carbohidratos, a un anticuerpo específico para la estructura de carbohidratos, a una vacuna que comprende el antígeno o el anticuerpo, al uso del antígeno, el anticuerpo o la vacuna, y a los métodos de tratamiento y métodos de fabricacion. Reivindicacion 1: Un antígeno que comprende un carbohidrato correspondiente a la formula estructural Gala1-3GalNAcb1-4(Fuca1-3)GlcNAc (en lo sucesivo: Gal-LDNF). Reivindicacion 2: El antígeno de acuerdo con la reivindicacion 1, que comprende la Gal-LDNF en una estructura química de la formula: Gal-LDNF-R, caracterizado porque R denota una estructura inmunogénica, a la cual se adjunta la unidad de GlcNAc de la Gal-LDNF. Reivindicacion 3: El antígeno de acuerdo con la reivindicacion 2, caracterizado porque la estructura inmunogénica R se selecciona entre el grupo que consiste en carbohidratos, proteínas y lípidos. Reivindicacion 5: El antígeno de acuerdo con la reivindicacion 4, caracterizado porque R2 comprende, adicionalmente, una porcion de diaminopiridina que adjunta R2 a R1.The present application refers to the field of veterinary parasitic immunology. More specifically, the application refers to a carbohydrate structure useful for immunoprotective treatment and for the prevention or reduction of infections caused by parasitic nematodes in ruminants. Particularly, the application refers to an antigen comprising the carbohydrate structure, a specific antibody for the carbohydrate structure, a vaccine comprising the antigen or the antibody, the use of the antigen, the antibody or the vaccine, and treatment methods and manufacturing methods. Claim 1: An antigen comprising a carbohydrate corresponding to the structural formula Gala1-3GalNAcb1-4 (Fuca1-3) GlcNAc (hereinafter: Gal-LDNF). Claim 2: The antigen according to claim 1, comprising Gal-LDNF in a chemical structure of the formula: Gal-LDNF-R, characterized in that R denotes an immunogenic structure, to which the GlcNAc unit of the Gal-LDNF. Claim 3: The antigen according to claim 2, characterized in that the immunogenic structure R is selected from the group consisting of carbohydrates, proteins and lipids. Claim 5: The antigen according to claim 4, characterized in that R2 additionally comprises a portion of diaminopyridine that attaches R2 to R1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09159945 | 2009-05-11 | ||
US17742209P | 2009-05-12 | 2009-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR076555A1 true AR076555A1 (en) | 2011-06-22 |
Family
ID=40941929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100101582A AR076555A1 (en) | 2009-05-11 | 2010-05-10 | GLICAN ANTIGEN. USE. ANTIBODY. VACCINE. METHOD FOR MANUFACTURING VACCINE |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR076555A1 (en) |
UY (1) | UY32621A (en) |
WO (1) | WO2010130683A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11046988B2 (en) | 2014-08-04 | 2021-06-29 | Synaffix B.V. | Process for the modification of a glycoprotein using a β-(1,4)-N-acetylgalactosaminyl transferase or a mutant thereof |
NO3134520T3 (en) | 2015-04-23 | 2018-05-19 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPS021402A0 (en) * | 2002-01-30 | 2002-02-21 | Agresearch Limited | Novel monoclonal antibody and nematode larval antigens |
-
2010
- 2010-05-10 UY UY0001032621A patent/UY32621A/en not_active Application Discontinuation
- 2010-05-10 WO PCT/EP2010/056353 patent/WO2010130683A1/en active Application Filing
- 2010-05-10 AR ARP100101582A patent/AR076555A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2010130683A1 (en) | 2010-11-18 |
UY32621A (en) | 2010-12-31 |
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