AR070368A2 - PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION - Google Patents
PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITIONInfo
- Publication number
- AR070368A2 AR070368A2 ARP090100505A AR070368A2 AR 070368 A2 AR070368 A2 AR 070368A2 AR P090100505 A ARP090100505 A AR P090100505A AR 070368 A2 AR070368 A2 AR 070368A2
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- AR
- Argentina
- Prior art keywords
- vaccine composition
- composition
- metal salt
- antigen
- preparation
- Prior art date
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Reivindicacion 1: Un procedimiento para la preparacion de una composicion de vacuna que comprende un inmunoestimulante que es monofosforil lípido A o un derivado del mismo o un oligonucleotido que contiene un CpG, un antígeno y una sal metálica, dicho proceso caracterizado porque comprende: a) absorber el antígeno sobre una primera partícula de sal metálica; b) absorber el inmunoestimulante sobre una segunda partícula de sal metálica; y c) mezclar los productos de los pasos (a) y (b). Reivindicacion 6: Una composicion de vacuna caracterizada porque se obtiene mediante el proceso de cualquiera de las reivindicaciones 1 a 5. Reivindicacion 7: Uso de una composicion de vacuna de acuerdo con cualquiera de las reivindicaciones 1 a 5, caracterizado porque es para preparar un medicamento util para el tratamiento inmunoterapéutico de infecciones virales, bacterianas, de parásitos, alergia o cáncer.Claim 1: A process for the preparation of a vaccine composition comprising an immunostimulant that is monophosphoryl lipid A or a derivative thereof or an oligonucleotide containing a CpG, an antigen and a metal salt, said process characterized in that it comprises: a) absorb the antigen on a first metal salt particle; b) absorb the immunostimulant on a second metal salt particle; and c) mix the products of steps (a) and (b). Claim 6: A vaccine composition characterized in that it is obtained by the process of any of claims 1 to 5. Claim 7: Use of a vaccine composition according to any of claims 1 to 5, characterized in that it is for preparing a medicament Useful for the immunotherapeutic treatment of viral, bacterial, parasite, allergy or cancer infections.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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ARP090100505 AR070368A2 (en) | 2009-02-12 | 2009-02-12 | PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP090100505 AR070368A2 (en) | 2009-02-12 | 2009-02-12 | PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION |
Publications (1)
Publication Number | Publication Date |
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AR070368A2 true AR070368A2 (en) | 2010-03-31 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ARP090100505 AR070368A2 (en) | 2009-02-12 | 2009-02-12 | PROCEDURE FOR THE PREPARATION OF A VACCINE COMPOSITION THAT INCLUDES AN IMMUNOSTIMULATING AN ANTIGEN AND A METAL SALT AND USE OF SUCH COMPOSITION TO PREPARE A MEDICINAL PRODUCT. VACCINE COMPOSITION |
Country Status (1)
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AR (1) | AR070368A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10837018B2 (en) | 2013-07-25 | 2020-11-17 | Exicure, Inc. | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
US11123294B2 (en) | 2014-06-04 | 2021-09-21 | Exicure Operating Company | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
-
2009
- 2009-02-12 AR ARP090100505 patent/AR070368A2/en active IP Right Grant
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10837018B2 (en) | 2013-07-25 | 2020-11-17 | Exicure, Inc. | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
US10894963B2 (en) | 2013-07-25 | 2021-01-19 | Exicure, Inc. | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
US11123294B2 (en) | 2014-06-04 | 2021-09-21 | Exicure Operating Company | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
US11957788B2 (en) | 2014-06-04 | 2024-04-16 | Exicure Operating Company | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
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