AR070003A1 - NAFTALENIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NAFTALENIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
AR070003A1
AR070003A1 ARP080102854A ARP080102854A AR070003A1 AR 070003 A1 AR070003 A1 AR 070003A1 AR P080102854 A ARP080102854 A AR P080102854A AR P080102854 A ARP080102854 A AR P080102854A AR 070003 A1 AR070003 A1 AR 070003A1
Authority
AR
Argentina
Prior art keywords
disorders
pharmaceutical compositions
insomnia
disease
treatment
Prior art date
Application number
ARP080102854A
Other languages
Spanish (es)
Inventor
Pascal Berthelot
Mark Millan
Said Yous
Michael Spedding
Ahmed Sabaouni
Mohamed Ettaoussi
Daniel-Henri Caignard
Philippe Delagrange
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of AR070003A1 publication Critical patent/AR070003A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Reivindicacion 1: Compuesto de formula (1): o N-[2-(7-fluoro-1-naftil)etil]acetamida, así como sus sales de adicion a una base aceptable farmacéuticamente. Reivindicacion 5: Composiciones farmacéuticas segun la reivindicacion 3 utiles para la fabricacion de medicamentos para el tratamiento de trastornos del sueno, estrés, ansiedad, depresion mayor o depresiones estacionales, patologías cardiovasculares, patologías del sistema digestivo, insomnios y fatigas debidos a diferencias horarias, esquizofrenia, ataques de pánico, melancolía, trastornos del apetito, obesidad, insomnio, trastornos psicoticos, epilepsia, diabetes, enfermedad de Parkinson, demencia senil, diversos trastornos asociados al envejecimiento normal o patologico, migrana, pérdidas de memoria, enfermedad de Alzheimer, trastornos de la circulacion cerebral, así como en las disfunciones sexuales, como inhibidores de la ovulacion, inmunomoduladores y en el tratamiento de los cánceres.Claim 1: Compound of formula (1): or N- [2- (7-fluoro-1-naphthyl) ethyl] acetamide, as well as its addition salts to a pharmaceutically acceptable base. Claim 5: Pharmaceutical compositions according to claim 3 useful for the manufacture of medicaments for the treatment of sleep disorders, stress, anxiety, major depression or seasonal depressions, cardiovascular pathologies, digestive system pathologies, insomnia and fatigue due to time differences, schizophrenia , panic attacks, melancholy, appetite disorders, obesity, insomnia, psychotic disorders, epilepsy, diabetes, Parkinson's disease, senile dementia, various disorders associated with normal or pathological aging, migraine, memory loss, Alzheimer's disease, disorders of cerebral circulation, as well as in sexual dysfunctions, such as ovulation inhibitors, immunomodulators and in the treatment of cancers.

ARP080102854A 2007-07-02 2008-07-02 NAFTALENIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AR070003A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0704745A FR2918368B1 (en) 2007-07-02 2007-07-02 NOVEL NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Publications (1)

Publication Number Publication Date
AR070003A1 true AR070003A1 (en) 2010-03-10

Family

ID=39048929

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080102854A AR070003A1 (en) 2007-07-02 2008-07-02 NAFTALENIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (3)

Country Link
AR (1) AR070003A1 (en)
FR (1) FR2918368B1 (en)
WO (1) WO2009022062A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104292126B (en) * 2014-08-14 2016-08-24 广东东阳光药业有限公司 Naphthalene derivatives and the application on medicine thereof
CN104292125B (en) * 2014-08-14 2016-06-01 广东东阳光药业有限公司 Naphthalene derivatives and the application on medicine thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK72693D0 (en) * 1993-06-18 1993-06-18 Lundbeck & Co As H COMPOUNDS

Also Published As

Publication number Publication date
FR2918368B1 (en) 2009-08-28
FR2918368A1 (en) 2009-01-09
WO2009022062A1 (en) 2009-02-19

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