AR068733A1 - PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND - Google Patents

PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND

Info

Publication number
AR068733A1
AR068733A1 ARP080104335A ARP080104335A AR068733A1 AR 068733 A1 AR068733 A1 AR 068733A1 AR P080104335 A ARP080104335 A AR P080104335A AR P080104335 A ARP080104335 A AR P080104335A AR 068733 A1 AR068733 A1 AR 068733A1
Authority
AR
Argentina
Prior art keywords
alpha
chloro
solvent
toluidine
dinitro
Prior art date
Application number
ARP080104335A
Other languages
Spanish (es)
Original Assignee
Ishihara Sangyo Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ishihara Sangyo Kaisha filed Critical Ishihara Sangyo Kaisha
Publication of AR068733A1 publication Critical patent/AR068733A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Dado que el fluazinam resulta excelente como un ingrediente activo de los pesticidas y es muy util, se desea producirlo eficientemente y de un modo adecuado mediante operaciones simples de bajo costo y de un modo inocuo para el medioambiente. Reivindicacion 1: Un proceso para producir 3-cloro-N-(3-cloro-5-trifluorometil-2-piridil)-, alfa, alfa, alfa-trifluoro-2,6-dinitro-p-toluidina, que comprende (1) un paso que consiste en hacer reaccionar 2-amino-3-cloro-5-trifluorometilpiridina y 2,4-dicloro-3,5-dinitrobenzotrifluoruro en presencia de un componente alcalino y al menos un miembro seleccionado del grupo de éteres, nitrilos y ésteres como un solvente, (2) un paso de neutralizacion o acidificacion de la mezcla de reaccion con un ácido y (3) un paso para la eliminacion del solvente de una mezcla que contiene 3-cloro-N-(3-cloro-5-trifluorometil-2-piridil)- alfa, alfa, alfa-trifluoro-2,6-dinitro-p-toluidina como el producto de reaccion y el solvente de reaccion por destilacion para precipitar los cristales del producto.Since fluazinam is excellent as an active ingredient in pesticides and is very useful, it is desired to produce it efficiently and in an appropriate way through simple low-cost operations and in an environmentally safe way. Claim 1: A process for producing 3-chloro-N- (3-chloro-5-trifluoromethyl-2-pyridyl) -, alpha, alpha, alpha-trifluoro-2,6-dinitro-p-toluidine, comprising (1 ) a step that involves reacting 2-amino-3-chloro-5-trifluoromethylpyridine and 2,4-dichloro-3,5-dinitrobenzotrifluoride in the presence of an alkaline component and at least one member selected from the group of ethers, nitriles and esters as a solvent, (2) a neutralization or acidification step of the reaction mixture with an acid and (3) a step for the removal of the solvent from a mixture containing 3-chloro-N- (3-chloro-5 -trifluoromethyl-2-pyridyl) - alpha, alpha, alpha-trifluoro-2,6-dinitro-p-toluidine as the reaction product and the reaction solvent by distillation to precipitate the crystals of the product.

ARP080104335A 2007-10-24 2008-10-03 PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND AR068733A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007276855 2007-10-24
JP2008062682 2008-03-12

Publications (1)

Publication Number Publication Date
AR068733A1 true AR068733A1 (en) 2009-12-02

Family

ID=40010754

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080104335A AR068733A1 (en) 2007-10-24 2008-10-03 PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND

Country Status (5)

Country Link
JP (1) JP2009242370A (en)
AR (1) AR068733A1 (en)
CL (1) CL2008003130A1 (en)
TW (1) TW200922923A (en)
WO (1) WO2009054210A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2008124866A (en) 2005-11-23 2009-12-27 Махтешим Кемикал Уэкс Лтд. (Il) METHOD FOR PRODUCING PYRIDINAMINES AND THEIR NEW POLYMORPHIC FORMS
CN106316937A (en) * 2015-06-29 2017-01-11 江苏威耳化工有限公司 Preparation method of fluazinam
CN109988103A (en) * 2017-12-29 2019-07-09 江苏扬农化工股份有限公司 A method of synthesis fluazinam

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6052146B2 (en) * 1979-12-25 1985-11-18 石原産業株式会社 N-pyridylaniline compounds, their production methods, and pest control agents containing them
RU2008124866A (en) * 2005-11-23 2009-12-27 Махтешим Кемикал Уэкс Лтд. (Il) METHOD FOR PRODUCING PYRIDINAMINES AND THEIR NEW POLYMORPHIC FORMS

Also Published As

Publication number Publication date
CL2008003130A1 (en) 2009-03-06
TW200922923A (en) 2009-06-01
WO2009054210A1 (en) 2009-04-30
JP2009242370A (en) 2009-10-22

Similar Documents

Publication Publication Date Title
AR083549A1 (en) HIGH PURITY PRECIPITATED CALCIUM CARBONATE PRODUCTION
AR057564A1 (en) QUICK ACID HYDROLYSIS PROCESS OF LIGNOCELLULOSIC MATERIAL AND A HYDROLYSIS REACTOR
BRPI0810431A8 (en) PROCESS FOR IMPROVED USE OF THE PRODUCTION POTENTIAL OF TRANSGENIC PLANTS
AR074637A1 (en) ACID ADDITION SALT FORMS OF R - (+) - N-PROPARGIL-1-AMINOINDANO (THAT IS, RASAGILINE BASE), A FORMULA COMPOUND (1), PROCESSES TO PREPARE AND INSULATE THEM AND USES OF THE SAME
AR074845A1 (en) SYNTHESIS PROCEDURE OF IVABRADINE AND ITS ADDITION SALTS TO A PHARMACEUTICALLY ACCEPTABLE ACID
RS54219B1 (en) Process for the preparation of 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy}-n-methylpyridine-2-carboxamide, its salts and monohydrate
RU2013120972A (en) MAGNESIUM HYDROXIDE WITH A HIGH RELATIONSHIP OF CRYSTAL SIZES
PE20110277A1 (en) COMPOSITION THAT INCLUDES PEROXIAACETIC AND L-LACTIC ACID IN THE HYGIENIZATION OF AGRICULTURAL PRODUCTS
AR087929A1 (en) METHOD FOR PREPARING A WATER CONCENTRATED COMPOSITION OF GLIFOSATO WITH A MIXTURE OF AMINA SALTS
NZ601040A (en) Method of producing acrylic and methacrylic acid
AR059286A1 (en) PROCESS TO PREPARE VORICONAZOL, A POLYMORPHIC FORM OF AN INTERMEDIARY OF THE SAME AND ITS USE
BR112014028049A2 (en) peroxygen release compositions and method for their production
AR107494A1 (en) PROCESS FOR THE PREPARATION OF OSIMERTINB (AZD9291) OR A SALT THEREOF, AND "AZD9291 ANILINE" OR A SALT THEREOF
AR068801A1 (en) PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND AS ACTIVE INGREDIENT OF PESTICIDES
AR068733A1 (en) PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND
BR112012033462A2 (en) process for preparing formic acid
AR057345A1 (en) PROCESS TO PREPARE CIANHYDRIC ACID SALTS
MX2018000196A (en) Process for the preparation of a furfural derivative.
BR112015007192A2 (en) method for producing equilibrium peracetic acid and equilibrium peracetic acid obtainable by the method
AR082370A1 (en) HERBICIDE SALT PREPARATION PROCESS
AR073807A1 (en) PROCESS TO PREPARE SUNITINIB MALATE, SALT OF A WEAKER ACID THAN MALATE AS A INTERMEDIARY COMPOUND, AND PROCESS TO PREPARE SUCH INTERMEDIARY SALT.
AR110997A1 (en) PROCESS FOR THE PREPARATION OF 2-CYANIMIMIDAZOL COMPOUNDS
AR095548A1 (en) PREPARATION OF 4-AMINO-2,4-DIOXOBUTANOIC ACID
MX2013003581A (en) Process for producing granules comprising one or more complexing agent salts.
AR071540A1 (en) PROCESS FOR THE PRODUCTION OF A TOLUIDINE COMPOUND

Legal Events

Date Code Title Description
FB Suspension of granting procedure