AR068664A1 - Anticuerpos monocionales humanizados modificadores de enfermedades cancerosas ( cdmab ) y su uso, para el diagnostico y tratamiento del cancer - Google Patents
Anticuerpos monocionales humanizados modificadores de enfermedades cancerosas ( cdmab ) y su uso, para el diagnostico y tratamiento del cancerInfo
- Publication number
- AR068664A1 AR068664A1 ARP080104340A ARP080104340A AR068664A1 AR 068664 A1 AR068664 A1 AR 068664A1 AR P080104340 A ARP080104340 A AR P080104340A AR P080104340 A ARP080104340 A AR P080104340A AR 068664 A1 AR068664 A1 AR 068664A1
- Authority
- AR
- Argentina
- Prior art keywords
- cdmab
- antibodies
- treatment
- monotional
- cancerose
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title 1
- 239000003607 modifier Substances 0.000 title 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 230000007402 cytotoxic response Effects 0.000 abstract 1
- 230000003013 cytotoxicity Effects 0.000 abstract 1
- 231100000135 cytotoxicity Toxicity 0.000 abstract 1
- 208000013210 hematogenous Diseases 0.000 abstract 1
- 229940047124 interferons Drugs 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 108700012359 toxins Proteins 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
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- A—HUMAN NECESSITIES
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K51/1072—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3023—Lung
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
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- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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Abstract
La presente solicitud se refiere al estadiaje diagnostico y tratamiento de enfermedades cancerosas (para tumores primarios y metástasis de tumores), particularmente a la mediacion de citotoxicidad de células de tumores; y más particularmente al uso de anticuerpos que modifican enfermedades cancerosas (CDMAB), opcionalmente en combinacion con uno o más CMAB/agentes quimioterapéuticos, como un medio para iniciar la respuesta citotoxica. Además se refiere a ensayos de union, que utilizan el CDMAB. Los anticuerpos anti-cáncer se pueden conjugar a toxinas, enzimas, compuestos radioactivos, citoquinas, interferones, porciones diana o reporteras y células hematogenas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97721507P | 2007-10-03 | 2007-10-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR068664A1 true AR068664A1 (es) | 2009-11-25 |
Family
ID=40525805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080104340A AR068664A1 (es) | 2007-10-03 | 2008-10-03 | Anticuerpos monocionales humanizados modificadores de enfermedades cancerosas ( cdmab ) y su uso, para el diagnostico y tratamiento del cancer |
Country Status (4)
Country | Link |
---|---|
US (1) | US20090104115A1 (es) |
AR (1) | AR068664A1 (es) |
PE (1) | PE20090832A1 (es) |
WO (1) | WO2009043166A1 (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2471206A1 (en) * | 2001-12-21 | 2003-07-10 | Arius Research, Inc. | Individualized anti-cancer antibodies |
-
2008
- 2008-10-02 US US12/244,312 patent/US20090104115A1/en not_active Abandoned
- 2008-10-02 WO PCT/CA2008/001749 patent/WO2009043166A1/en active Application Filing
- 2008-10-03 AR ARP080104340A patent/AR068664A1/es not_active Application Discontinuation
- 2008-10-03 PE PE2008001729A patent/PE20090832A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2009043166A1 (en) | 2009-04-09 |
PE20090832A1 (es) | 2009-07-02 |
US20090104115A1 (en) | 2009-04-23 |
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Date | Code | Title | Description |
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FA | Abandonment or withdrawal |