AR068115A1 - DERIVED FROM PIRAZOLCARBOXILICO ACID PRODUCTION METHOD OF THE SAME AND FUNGICIDE - Google Patents

DERIVED FROM PIRAZOLCARBOXILICO ACID PRODUCTION METHOD OF THE SAME AND FUNGICIDE

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Publication number
AR068115A1
AR068115A1 ARP080103727A ARP080103727A AR068115A1 AR 068115 A1 AR068115 A1 AR 068115A1 AR P080103727 A ARP080103727 A AR P080103727A AR P080103727 A ARP080103727 A AR P080103727A AR 068115 A1 AR068115 A1 AR 068115A1
Authority
AR
Argentina
Prior art keywords
group
substituted
alkyl
heteroaryl
cycloalkenyl
Prior art date
Application number
ARP080103727A
Other languages
Spanish (es)
Inventor
Chiba Yutaka
Kouno Toshiyuki
Banba Shinichi
Tomura Naofumi
Shibata Chie
Akase Tomohisa
Original Assignee
Mitsui Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Chemicals Inc filed Critical Mitsui Chemicals Inc
Publication of AR068115A1 publication Critical patent/AR068115A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/20—N-Aryl derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/30—Derivatives containing the group >N—CO—N aryl or >N—CS—N—aryl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Abstract

La presente proporciona un fungicida que nuestra una accion de control de enfermedades agrícolas y es inocuo, o en gran parte inocuo, para los cultivos. Reivindicacion 1: Derivado de ácido pirazolcarboxílico representado por la siguiente formula (1),en la que R1 representa un átomo de hidrogeno o un grupo alquilo C1-6; R2 y R3 representan cada uno independientemente un átomo de hidrogeno, un grupo alquilo C1-6, haloalquilo C1-6, alcoxilo C1-6, haloalcoxilo C1-6, alquiltio C1-6, haloalquiltio C1-6, alquilsulfinilo C1-6, haloalquilsulfinilo C1-6, alquilsulfonilo C1-6, haloalquilsulfonilo C1-6, un átomo de halogeno, un grupo ciano o un grupo nitro, siendo al menos uno de R2 y R3 un grupo haloalquilo C1-6; A representa -OR4, -SR5, NR6R7 o -NR8NR9R10; R4 representa un grupo alquilo C3-12, cicloalquilo C3-6, alquenilo C2-6, cicloalquenilo C3-6, alquinilo C2-6, alquilo C1-6 sustituido con un grupo heteroarilo que puede estar sustituido, un grupo arilo que puede estar sustituido o un grupo heteroarilo que puede estar sustituido; R5 representa un grupo alquilo C1-12, cicloalquilo C3-6, alquenilo C2-6, cicloalquenilo C3-6, alquinilo C2-6, alquilo C1-6 sustituido con un grupo heteroarilo que puede estar sustituido, un grupo arilo que puede estar sustituido o un grupo heteroarilo que puede estar sustituido; R6 representa un átomo de hidrogeno, alquilo C1-12, alquenilo C2-6, cicloalquenilo C3-6, alquinilo C2-6, un grupo heteroarilo que puede estar sustituido, acilo, alcoxicarbonilo, ariloxicarbonilo, alquilsulfonilo, arilsulfonilo, alquilaminocarbonilo o un grupo arilaminocarbonilo, cuando R7 representa un grupo alquilo C5-12, alquenilo C2-6, cicloalquenilo C3-6, alquinilo C2-6, alquilo C1-6 sustituido con un grupo carboxilo o un grupo alquilo C1-6 sustituido con un grupo alcoxicarbonilo C1-6; R6 representa un grupo alquenilo C2-6, cicloalquenilo C3-6, alquinilo C2-6, arilo que puede estar sustituido, heteroarilo que puede estar sustituido, acilo, alcoxicarbonilo, ariloxicarbonilo, alquilsulfonilo, arilsulfonilo, alquilaminocarbonilo o un grupo arilaminocarbonilo, cuando R7 representa un grupo cicloalquilo C3-6, un grupo arilo que puede estar sustituido o un heteroarilo que puede estar sustituido, y R8, R9 y R10 representan cada uno independientemente H, alquilo C1-12, cicloalquilo C3-6, alquenilo C2-6, cicloalquenilo C3-6, alquinilo C2-6, alquilo C1-6 sustituido con un grupo heteroarilo que puede estar sustituido, arilo que puede estar sustituido, heteroarilo que puede estar sustituido, acilo, alcoxicarbonilo, ariloxicarbonilo, alquilsulfonilo, arilsulfonilo, alquilaminocarbonilo o un grupo arilaminocarbonilo, no siendo al menos uno de R8, R9 y R10 un átomo de hidrogeno, y pudiéndose unir entre sí R9 y R10 para formar un grupo de anillo heterocíclico que tiene de 2 a 5 átomos de carbono.This provides a fungicide that is an agricultural disease control action and is harmless, or largely harmless, for crops. Claim 1: Pyrazolecarboxylic acid derivative represented by the following formula (1), wherein R1 represents a hydrogen atom or a C1-6 alkyl group; R 2 and R 3 each independently represent a hydrogen atom, a C 1-6 alkyl group, C 1-6 haloalkyl, C 1-6 alkoxy, C 1-6 haloalkoxy, C 1-6 alkylthio, C 1-6 haloalkyl, C 1-6 alkylsulfinyl, haloalkylsulfinyl C1-6, C1-6 alkylsulfonyl, C1-6 haloalkylsulfonyl, a halogen atom, a cyano group or a nitro group, at least one of R2 and R3 being a C1-6 haloalkyl group; A represents -OR4, -SR5, NR6R7 or -NR8NR9R10; R4 represents a C3-12 alkyl, C3-6 cycloalkyl, C2-6 alkenyl, C3-6 cycloalkenyl, C2-6 alkynyl, C1-6 alkyl substituted with a heteroaryl group that may be substituted, an aryl group that can be substituted or a heteroaryl group that may be substituted; R5 represents a C1-12 alkyl group, C3-6 cycloalkyl, C2-6 alkenyl, C3-6 cycloalkenyl, C2-6 alkynyl, C1-6 alkyl substituted with a heteroaryl group which may be substituted, an aryl group which may be substituted or a heteroaryl group that may be substituted; R 6 represents a hydrogen atom, C 1-12 alkyl, C 2-6 alkenyl, C 3-6 cycloalkenyl, C 2-6 alkynyl, a heteroaryl group which may be substituted, acyl, alkoxycarbonyl, aryloxycarbonyl, alkylsulfonyl, arylsulfonyl, alkylaminocarbonyl or an arylaminocarbonyl group , when R7 represents a C5-12 alkyl, C2-6 alkenyl, C3-6 cycloalkenyl, C2-6 alkynyl, C1-6 alkyl substituted with a carboxyl group or a C1-6 alkyl group substituted with a C1-6 alkoxycarbonyl group ; R 6 represents a C 2-6 alkenyl group, C 3-6 cycloalkenyl, C 2-6 alkynyl, aryl that may be substituted, heteroaryl that may be substituted, acyl, alkoxycarbonyl, aryloxycarbonyl, alkylsulfonyl, arylsulfonyl, alkylaminocarbonyl or an arylaminocarbonyl group, when R 7 represents a C3-6 cycloalkyl group, an aryl group that can be substituted or a heteroaryl that can be substituted, and R8, R9 and R10 each independently represent H, C1-12 alkyl, C3-6 cycloalkyl, C2-6 alkenyl, cycloalkenyl C3-6, C2-6 alkynyl, C1-6 alkyl substituted with a heteroaryl group which may be substituted, aryl which may be substituted, heteroaryl which may be substituted, acyl, alkoxycarbonyl, aryloxycarbonyl, alkylsulfonyl, arylsulfonyl, alkylaminocarbonyl or an arylaminocarbonyl group , at least one of R8, R9 and R10 being not a hydrogen atom, and R9 and R10 being able to join together to form a heterocyclic ring group having 2 to 5 carbon atoms

ARP080103727A 2007-08-29 2008-08-27 DERIVED FROM PIRAZOLCARBOXILICO ACID PRODUCTION METHOD OF THE SAME AND FUNGICIDE AR068115A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007222384 2007-08-29
PCT/JP2008/063278 WO2009028280A1 (en) 2007-08-29 2008-07-24 Pyrazolecarboxylic acid derivative, method for producing the same and bactericide

Publications (1)

Publication Number Publication Date
AR068115A1 true AR068115A1 (en) 2009-11-04

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ARP080103727A AR068115A1 (en) 2007-08-29 2008-08-27 DERIVED FROM PIRAZOLCARBOXILICO ACID PRODUCTION METHOD OF THE SAME AND FUNGICIDE

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JP (2) JPWO2009028280A1 (en)
AR (1) AR068115A1 (en)
CL (1) CL2008002554A1 (en)
TW (1) TW200916444A (en)
WO (1) WO2009028280A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2253617A1 (en) 2009-05-20 2010-11-24 Bayer CropScience AG Halogenated compounds as pesticides
US8987470B2 (en) 2010-10-27 2015-03-24 Solvay Sa Process for the preparation of pyrazole-4-carboxamides
HUE028418T2 (en) 2011-07-26 2016-12-28 Sanofi Sa 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
AR093195A1 (en) 2012-02-29 2015-05-27 Meiji Seika Pharma Co Ltd COMPOSITION FOR PEST CONTROL THAT INCLUDES AN IMINOPIRIDINE DERIVATIVE
US9394257B2 (en) 2012-10-16 2016-07-19 Tolero Pharmaceuticals, Inc. PKM2 modulators and methods for their use
KR102161867B1 (en) * 2013-01-30 2020-10-05 스미또모 가가꾸 가부시끼가이샤 Method for controlling arthropod pest
JP6213266B2 (en) * 2013-01-30 2017-10-18 住友化学株式会社 Amide compounds and their use for controlling harmful arthropods
CN104045634A (en) * 2014-06-06 2014-09-17 浙江工业大学 Pyrazolecarboxamide compound containing difluoromethyl as well as preparation method and application of pyrazolecarboxamide compound
CN105601618B (en) * 2016-01-11 2018-04-27 天津医科大学 Aromatic imides class compound and preparation method and application
AU2020245437A1 (en) 2019-03-22 2021-09-30 Sumitomo Pharma Oncology, Inc. Compositions comprising PKM2 modulators and methods of treatment using the same
JP2022527451A (en) * 2019-03-22 2022-06-02 スミトモ ダイニッポン ファーマ オンコロジー， インコーポレイテッド PKM2 Modulator and How to Use It

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0253775A (en) * 1988-08-18 1990-02-22 Nissan Chem Ind Ltd Pyrazole carboxamide derivative and herbicide
JPH02129171A (en) * 1988-11-08 1990-05-17 Nissan Chem Ind Ltd Pyrazolecarboxanilide derivative and agent for controlling harmful life
JPH09176125A (en) * 1995-05-31 1997-07-08 Nissan Chem Ind Ltd 5-pyrazolecarboxylic acid amide derivative and plant blight controlling agent
JPH09176124A (en) * 1995-12-25 1997-07-08 Nissan Chem Ind Ltd Pyrazoline derivative and plant blight controlling agent
WO2002083647A1 (en) * 2001-04-06 2002-10-24 Nihon Nohyaku Co., Ltd. Pyrazolecarboxamide derivative, intermediate therefor, and pest control agent containing the same as active ingredient

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JPWO2009028280A1 (en) 2010-11-25
WO2009028280A1 (en) 2009-03-05
TW200916444A (en) 2009-04-16
JP2009073823A (en) 2009-04-09
CL2008002554A1 (en) 2009-01-16

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