AR067471A1 - A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSIS - Google Patents

A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSIS

Info

Publication number
AR067471A1
AR067471A1 ARP080102932A ARP080102932A AR067471A1 AR 067471 A1 AR067471 A1 AR 067471A1 AR P080102932 A ARP080102932 A AR P080102932A AR P080102932 A ARP080102932 A AR P080102932A AR 067471 A1 AR067471 A1 AR 067471A1
Authority
AR
Argentina
Prior art keywords
pertussis
prn
pertactin
vaccine
component
Prior art date
Application number
ARP080102932A
Other languages
Spanish (es)
Inventor
M L Mago
Rajesh Jain
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of AR067471A1 publication Critical patent/AR067471A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Abstract

Un componente de vacuna anti-pertusis obteniendo antígeno Pertactina (PRN) desde Bordetella pertussis. Un proceso simplificado para la extraccion y purificacion de Pertactina (PRN). La Pertactina obtenida por este procedimiento tiene un nivel de pureza mayor de 90% y el procedimiento usado en la presente previene la pérdida de PRN al evitar pasos complejos de procesamiento. La proteína de membrana externa (OMP) purificada por el procedimiento de la presente utiliza un proceso simplificado y es util en la preparacion de Vacunas Acelulares Anti-Pertussis, tanto sola como parte de combinaciones de vacunas. Reivindicacion 15: Un procedimiento para usar el componente de vacuna segun la reivindicacion 1, caracterizado porque comprende administrar a un sujeto necesitado de ello una cantidad del componente de vacuna.A component of anti-pertussis vaccine obtaining Pertactin antigen (PRN) from Bordetella pertussis. A simplified process for the extraction and purification of Pertactin (PRN). The Pertactin obtained by this procedure has a purity level greater than 90% and the procedure used herein prevents the loss of PRN by avoiding complex processing steps. The outer membrane protein (OMP) purified by the process herein uses a simplified process and is useful in the preparation of Anti-Pertussis Acellular Vaccines, both alone and as part of vaccine combinations. Claim 15: A method for using the vaccine component according to claim 1, characterized in that it comprises administering to a subject in need a quantity of the vaccine component.

ARP080102932A 2007-07-31 2008-07-07 A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSIS AR067471A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1618DE2007 2007-07-31

Publications (1)

Publication Number Publication Date
AR067471A1 true AR067471A1 (en) 2009-10-14

Family

ID=40303927

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080102932A AR067471A1 (en) 2007-07-31 2008-07-07 A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSIS

Country Status (3)

Country Link
AR (1) AR067471A1 (en)
CL (1) CL2008002003A1 (en)
WO (1) WO2009016651A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010131111A1 (en) * 2009-05-11 2010-11-18 Novartis Ag Antigen purification process for pertactin antigen
US10329323B2 (en) * 2014-07-25 2019-06-25 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Method for purifying antibodies using PBS
KR102426041B1 (en) * 2017-08-01 2022-07-29 주식회사 녹십자 Method for obtaining bordetella pertussis related protein comprising processes of freezing and thawing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007657D0 (en) * 1990-04-04 1990-05-30 Connaught Lab Purification of a pertussis outer membrane protein(omp69)
EP1762246A1 (en) * 1996-07-02 2007-03-14 Sanofi Pasteur Limited Multivalent DTP-Polio vaccines

Also Published As

Publication number Publication date
CL2008002003A1 (en) 2008-11-03
WO2009016651A1 (en) 2009-02-05

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