AR067471A1 - A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSIS - Google Patents
A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSISInfo
- Publication number
- AR067471A1 AR067471A1 ARP080102932A ARP080102932A AR067471A1 AR 067471 A1 AR067471 A1 AR 067471A1 AR P080102932 A ARP080102932 A AR P080102932A AR P080102932 A ARP080102932 A AR P080102932A AR 067471 A1 AR067471 A1 AR 067471A1
- Authority
- AR
- Argentina
- Prior art keywords
- pertussis
- prn
- pertactin
- vaccine
- component
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
Un componente de vacuna anti-pertusis obteniendo antígeno Pertactina (PRN) desde Bordetella pertussis. Un proceso simplificado para la extraccion y purificacion de Pertactina (PRN). La Pertactina obtenida por este procedimiento tiene un nivel de pureza mayor de 90% y el procedimiento usado en la presente previene la pérdida de PRN al evitar pasos complejos de procesamiento. La proteína de membrana externa (OMP) purificada por el procedimiento de la presente utiliza un proceso simplificado y es util en la preparacion de Vacunas Acelulares Anti-Pertussis, tanto sola como parte de combinaciones de vacunas. Reivindicacion 15: Un procedimiento para usar el componente de vacuna segun la reivindicacion 1, caracterizado porque comprende administrar a un sujeto necesitado de ello una cantidad del componente de vacuna.A component of anti-pertussis vaccine obtaining Pertactin antigen (PRN) from Bordetella pertussis. A simplified process for the extraction and purification of Pertactin (PRN). The Pertactin obtained by this procedure has a purity level greater than 90% and the procedure used herein prevents the loss of PRN by avoiding complex processing steps. The outer membrane protein (OMP) purified by the process herein uses a simplified process and is useful in the preparation of Anti-Pertussis Acellular Vaccines, both alone and as part of vaccine combinations. Claim 15: A method for using the vaccine component according to claim 1, characterized in that it comprises administering to a subject in need a quantity of the vaccine component.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1618DE2007 | 2007-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR067471A1 true AR067471A1 (en) | 2009-10-14 |
Family
ID=40303927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080102932A AR067471A1 (en) | 2007-07-31 | 2008-07-07 | A COMPONENT OF ANTI-PERTUSSIS VACCINE AND SIMPLIFIED PROCEDURE TO OBTAIN PERTACTIN (PRN) FROM BORDETELLA PERTUSSIS |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR067471A1 (en) |
CL (1) | CL2008002003A1 (en) |
WO (1) | WO2009016651A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010131111A1 (en) * | 2009-05-11 | 2010-11-18 | Novartis Ag | Antigen purification process for pertactin antigen |
US10329323B2 (en) * | 2014-07-25 | 2019-06-25 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Method for purifying antibodies using PBS |
KR102426041B1 (en) * | 2017-08-01 | 2022-07-29 | 주식회사 녹십자 | Method for obtaining bordetella pertussis related protein comprising processes of freezing and thawing |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9007657D0 (en) * | 1990-04-04 | 1990-05-30 | Connaught Lab | Purification of a pertussis outer membrane protein(omp69) |
EP1762246A1 (en) * | 1996-07-02 | 2007-03-14 | Sanofi Pasteur Limited | Multivalent DTP-Polio vaccines |
-
2008
- 2008-05-30 WO PCT/IN2008/000343 patent/WO2009016651A1/en active Application Filing
- 2008-07-07 AR ARP080102932A patent/AR067471A1/en unknown
- 2008-07-09 CL CL2008002003A patent/CL2008002003A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CL2008002003A1 (en) | 2008-11-03 |
WO2009016651A1 (en) | 2009-02-05 |
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