AR060856A1 - IMPROVED PROCEDURE TO PREPARE GABAPENTINE - Google Patents

IMPROVED PROCEDURE TO PREPARE GABAPENTINE

Info

Publication number
AR060856A1
AR060856A1 ARP070101943A ARP070101943A AR060856A1 AR 060856 A1 AR060856 A1 AR 060856A1 AR P070101943 A ARP070101943 A AR P070101943A AR P070101943 A ARP070101943 A AR P070101943A AR 060856 A1 AR060856 A1 AR 060856A1
Authority
AR
Argentina
Prior art keywords
acid
gabapentine
prepare
aminomethyl
salt
Prior art date
Application number
ARP070101943A
Other languages
Spanish (es)
Inventor
Patrick Gerard Thomas Kelleher
Simon Benjamin Davies
William Eugene Tully
Original Assignee
Pfizer Science & Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IE20060358A external-priority patent/IE20060358A1/en
Priority claimed from PCT/IE2006/000049 external-priority patent/WO2007129286A1/en
Application filed by Pfizer Science & Tech Ltd filed Critical Pfizer Science & Tech Ltd
Publication of AR060856A1 publication Critical patent/AR060856A1/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento en un unico recipiente para preparar ácido 1-(aminometil)-ciclohexanoacético o sales farmacéuticamente aceptables del mismo que comprende las etapas de hidrolizar éster etílico del ácido 1-cianociclohexanoacético con un hidroxido de potasio, sodio o litio para formar una sal del ácido 1-cianociclohexanoacético; hidrogenar in-situ la sal del ácido 1-cianociclohexanoacético en presencia de un catalizador para formar la sal del ácido 1-(aminometil)-ciclohexanoacético; y aislar el ácido 1-(aminometil)-ciclohexanoacético.A process in a single container for preparing 1- (aminomethyl) -cyclohexaneacetic acid or pharmaceutically acceptable salts thereof comprising the steps of hydrolyzing 1-cyanocyclohexane acetic acid ethyl ester with a potassium, sodium or lithium hydroxide to form a salt of the acid 1-cyanocyclohexaneacetic acid; hydrogenate in-situ the salt of 1-cyanocyclohexaneacetic acid in the presence of a catalyst to form the salt of 1- (aminomethyl) -cyclohexaneacetic acid; and isolate 1- (aminomethyl) -cyclohexaneacetic acid.

ARP070101943A 2006-05-05 2007-05-04 IMPROVED PROCEDURE TO PREPARE GABAPENTINE AR060856A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE20060358A IE20060358A1 (en) 2006-05-05 2006-05-05 A process for preparing gabapentin
PCT/IE2006/000049 WO2007129286A1 (en) 2006-05-05 2006-05-05 Process for preparing gabapentin

Publications (1)

Publication Number Publication Date
AR060856A1 true AR060856A1 (en) 2008-07-16

Family

ID=38767186

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070101943A AR060856A1 (en) 2006-05-05 2007-05-04 IMPROVED PROCEDURE TO PREPARE GABAPENTINE

Country Status (3)

Country Link
JP (1) JP2007297386A (en)
AR (1) AR060856A1 (en)
TW (1) TW200812939A (en)

Also Published As

Publication number Publication date
TW200812939A (en) 2008-03-16
JP2007297386A (en) 2007-11-15

Similar Documents

Publication Publication Date Title
BR112014026175A2 (en) bale continuous forming apparatus with a pivot bale support construction
MY182428A (en) Crystalline forms of a prolyl hydroxylase inhibitor
GT200600420A (en) LISINA NOVEDOUS SALTS OF ACID DERIVATIVES 4 - ((PHENOXIALQUIL) UNCLE) -PHENOXYACETIC
AR074894A1 (en) PROCEDURE TO PURIFY AN ALCOHOL FROM A FERMENTATION BRASS USING A DOWNLOAD FILM EVAPORATOR, OF SHAKED FILM OR SHORT FILM
CL2011002854A1 (en) Computer-implemented method to transition between slides.
ES2666720T3 (en) Composition to prevent or treat cervical cancer with an immunity enhancer against human papillomavirus
AR069616A1 (en) PROCESS FOR PRODUCTION OF BIODIESEL AND ESTERES OF FATTY ACIDS
AR092656A1 (en) STEAM REFORMING CATALYST
BR112014014459A2 (en) oral care compositions
CU20120168A7 (en) PROCEDURE FOR THE PREPARATION OF 3,6,9-TRIS (CARBOXIMETHYL) -4- (ETOXIBENCIL) -CONDECANOICO CRISTALINO DIACIDE AND THE USE FOR THE PREPARATION OF PRIMOVIST®
AR075915A1 (en) PROCESS FOR OBTAINING PROPIONIC ACID DERIVATIVES
AR060856A1 (en) IMPROVED PROCEDURE TO PREPARE GABAPENTINE
CL2017002290A1 (en) Process for the manufacture of propionate products
JO2930B1 (en) New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
AR078137A1 (en) METHOD FOR THE PREPARATION OF NERAMEXANE
SA112330994B1 (en) New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
MX2011012233A (en) Topical retinoid solutions.
ES2556470T3 (en) Procedure for preparing [3 - [(6-chloro-3-pyridinyl) methyl] -2-thiazolidinyliden] cyanamide
IN2014MN01384A (en)
ES2421641T3 (en) Procedure for the preparation of valsartan
AR078138A1 (en) METHOD FOR THE PREPARATION OF 3,3,5,5-TETRAMETILCICLOHEXANONA
CL2015002251A1 (en) Pharmaceutical compositions containing dexketoprofen and tramadol
CR11163A (en) SALES MONOCLORHYDRATE OF AN INHIBITOR NDE HISTONA DEACETILASE
MY160928A (en) New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
RU2011106276A (en) METHOD FOR PRODUCING FULLERENOLS

Legal Events

Date Code Title Description
FB Suspension of granting procedure