AR059258A1 - METHODS TO INTERFER WITH THE GASTRIC ACID SECRETION INDUCED BY GLUCOCORTICOIDS - Google Patents
METHODS TO INTERFER WITH THE GASTRIC ACID SECRETION INDUCED BY GLUCOCORTICOIDSInfo
- Publication number
- AR059258A1 AR059258A1 ARP070100405A ARP070100405A AR059258A1 AR 059258 A1 AR059258 A1 AR 059258A1 AR P070100405 A ARP070100405 A AR P070100405A AR P070100405 A ARP070100405 A AR P070100405A AR 059258 A1 AR059258 A1 AR 059258A1
- Authority
- AR
- Argentina
- Prior art keywords
- gastric acid
- glucocorticoids
- interfer
- methods
- glucocorticoid
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/062—Gastritis or peptic ulcer disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Un método para alterar la secrecion de ácido gástrico inducida por glucocorticoides, que comprende poner en contacto células que expresan quinasa inducible por glucocorticoides del suero (SGK) con una sustancia que modula dicha quinasa inducible por glucocorticoides. Además, la presente se relaciona con el diagnostico y la identificacion de compuestos que pueden ser agonistas o antagonistas que son potencialmente utiles en la terapia de la secrecion patologica de ácido gástrico. Reivindicacion 1: Un método para alterar la secrecion de ácido gástrico que comprende poner en contacto células que expresan SGK1, SGK2 o SGK3 con una sustancia que modula las quinasas inducibles por glucocorticoides.A method for altering the secretion of gastric acid induced by glucocorticoids, which comprises contacting cells that express serum glucocorticoid-inducible kinase (SGK) with a substance that modulates said glucocorticoid-inducible kinase. In addition, this relates to the diagnosis and identification of compounds that may be agonists or antagonists that are potentially useful in the therapy of the pathological secretion of gastric acid. Claim 1: A method for altering gastric acid secretion comprising contacting cells expressing SGK1, SGK2 or SGK3 with a substance that modulates glucocorticoid inducible kinases.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06001934 | 2006-01-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR059258A1 true AR059258A1 (en) | 2008-03-19 |
Family
ID=38006823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070100405A AR059258A1 (en) | 2006-01-31 | 2007-01-31 | METHODS TO INTERFER WITH THE GASTRIC ACID SECRETION INDUCED BY GLUCOCORTICOIDS |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1979747A1 (en) |
JP (1) | JP2009531020A (en) |
AR (1) | AR059258A1 (en) |
AU (1) | AU2007211655A1 (en) |
CA (1) | CA2641325A1 (en) |
IL (1) | IL193081A0 (en) |
WO (1) | WO2007087985A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210008193A (en) * | 2019-07-10 | 2021-01-21 | 한양대학교 산학협력단 | Use of Sgk1 inhibitor for treating inflammatory neurologic disorders |
EP4232016A4 (en) * | 2020-10-26 | 2024-04-17 | Univ Of North Dakota | Use of small molecule fak activators to promote mucosal healing |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10346913A1 (en) * | 2003-10-09 | 2005-05-04 | Merck Patent Gmbh | acylhydrazone |
JP2007527876A (en) * | 2004-03-08 | 2007-10-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | Method for modifying insulin secretion |
RU2006135653A (en) * | 2004-03-11 | 2008-04-20 | Мерк Патент ГмбХ (DE) | METHODS Preventing Fibrosis |
CA2559136A1 (en) * | 2004-03-11 | 2005-10-13 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Methods for modulating glutamate receptors for treating neuropsychiatric disorders comprising the use of modulators of serum and glucocorticoid inducible kinases |
US20090136920A1 (en) * | 2004-04-30 | 2009-05-28 | Stefan Golz | Diagnostics and therapeutics for diseases associated with serum/glucocorticoid regulated kinase 1 (sgk1) |
-
2007
- 2007-01-17 AU AU2007211655A patent/AU2007211655A1/en not_active Abandoned
- 2007-01-17 JP JP2008552709A patent/JP2009531020A/en active Pending
- 2007-01-17 EP EP07702807A patent/EP1979747A1/en not_active Withdrawn
- 2007-01-17 WO PCT/EP2007/000350 patent/WO2007087985A1/en active Application Filing
- 2007-01-17 CA CA002641325A patent/CA2641325A1/en not_active Abandoned
- 2007-01-31 AR ARP070100405A patent/AR059258A1/en unknown
-
2008
- 2008-07-27 IL IL193081A patent/IL193081A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL193081A0 (en) | 2009-02-11 |
JP2009531020A (en) | 2009-09-03 |
WO2007087985A1 (en) | 2007-08-09 |
EP1979747A1 (en) | 2008-10-15 |
CA2641325A1 (en) | 2007-08-09 |
AU2007211655A1 (en) | 2007-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |