AR056591A1 - LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4) - Google Patents

LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4)

Info

Publication number
AR056591A1
AR056591A1 ARP060104709A ARP060104709A AR056591A1 AR 056591 A1 AR056591 A1 AR 056591A1 AR P060104709 A ARP060104709 A AR P060104709A AR P060104709 A ARP060104709 A AR P060104709A AR 056591 A1 AR056591 A1 AR 056591A1
Authority
AR
Argentina
Prior art keywords
tlr4
polypeptides
toll
simil
receiver
Prior art date
Application number
ARP060104709A
Other languages
Spanish (es)
Inventor
Valerie Odegar
Dennis William Powell
Original Assignee
Vaxinnate Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxinnate Corp filed Critical Vaxinnate Corp
Publication of AR056591A1 publication Critical patent/AR056591A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente proporciona nuevos polipéptidos ligandos para el receptor 4 simil Toll (TLR4). Los nuevos ligandos polipeptídicos modulan la senalizacion de TLR4 y de esta manera regulan la Respuesta Inmune Innata. La presente proporciona métodos para modular la senalizacion de TLR4 empleando los polipéptidos ligandos TLR4 de la misma. La presente también proporciona vacunas que comprenden los nuevos polipéptidos ligandos de TLR4 y un antígeno. Proporciona además métodos para estimular una respuesta inmune empleando los polipéptidos polipeptídicos de TLR4 y vacunas de la misma.This provides new ligand polypeptides for the 4-like Toll receptor (TLR4). The new polypeptide ligands modulate the signaling of TLR4 and thus regulate the Innate Immune Response. This provides methods to modulate TLR4 signaling using TLR4 ligand polypeptides thereof. This also provides vaccines comprising the new TLR4 ligand polypeptides and an antigen. It also provides methods to stimulate an immune response using TLR4 polypeptide polypeptides and vaccines thereof.

ARP060104709A 2005-10-28 2006-10-27 LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4) AR056591A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73159505P 2005-10-28 2005-10-28

Publications (1)

Publication Number Publication Date
AR056591A1 true AR056591A1 (en) 2007-10-10

Family

ID=38006399

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104709A AR056591A1 (en) 2005-10-28 2006-10-27 LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4)

Country Status (2)

Country Link
AR (1) AR056591A1 (en)
WO (1) WO2007053455A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106237316A (en) 2006-03-07 2016-12-21 法克斯因内特公司 The compositions comprising hemagglutinin, the method manufacturing it and the method using it
US7629135B2 (en) 2006-12-22 2009-12-08 The Board Of Trustees Of The University Of Illinois Toll-like receptor agonists and antagonists and methods of use thereof
RU2014140521A (en) 2012-03-08 2016-04-27 Новартис Аг ADJUVANT COMPOSITIONS OF BOOSTER VACCINES
US20150125486A1 (en) 2012-03-08 2015-05-07 Novartis Ag Adjuvanted formulations of pediatric antigens
EP2830631B1 (en) 2012-03-28 2017-11-22 University of Maryland, Baltimore Administration of eritoran or pharmaceutically acceptable salts thereof to treat orthomyxovirus infections
AU2013311702A1 (en) 2012-09-06 2015-02-19 Novartis Ag Combination vaccines with serogroup B meningococcus and D/T/P
SG11201502599TA (en) 2012-10-12 2015-05-28 Glaxosmithkline Biolog Sa Non-cross-linked acellular pertussis antigens for use in combination vaccines
CN105188747A (en) 2013-02-01 2015-12-23 葛兰素史密斯克莱生物公司 Intradermal delivery of immunological compositions comprising TOLL-like receptor agonists
US20160083424A1 (en) * 2013-04-26 2016-03-24 Oslo Universitetssykehus Hf Compositions and methods for targeting antigen-presenting cells
CN109310730A (en) 2016-02-17 2019-02-05 佩普蒂康姆有限责任公司 The peptide agonists and antagonist of TLR4 activation
AU2019216873A1 (en) * 2018-02-07 2020-08-20 Imugene Limited A vaccine composition and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants

Also Published As

Publication number Publication date
WO2007053455A2 (en) 2007-05-10
WO2007053455A3 (en) 2007-06-14

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