AR056245A1 - FUNCTIONAL RECONSTITUTED VIRAL MEMBRANES CONTAINING A COADYUVANT - Google Patents

FUNCTIONAL RECONSTITUTED VIRAL MEMBRANES CONTAINING A COADYUVANT

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Publication number
AR056245A1
AR056245A1 ARP040102097A ARP040102097A AR056245A1 AR 056245 A1 AR056245 A1 AR 056245A1 AR P040102097 A ARP040102097 A AR P040102097A AR P040102097 A ARP040102097 A AR P040102097A AR 056245 A1 AR056245 A1 AR 056245A1
Authority
AR
Argentina
Prior art keywords
coadyuvant
membranes
viral membranes
membranes containing
reconstituted viral
Prior art date
Application number
ARP040102097A
Other languages
Spanish (es)
Original Assignee
Bestewil Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bestewil Holding Bv filed Critical Bestewil Holding Bv
Publication of AR056245A1 publication Critical patent/AR056245A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Vacunas dirigidas contra antígenos, tales como las proteínas de membrana de patogenos o células tumorales. Método para formar membranas virales reconstruidos, con actividad de fusion de membranas, que son membranas con dos capas de lípidos que contienen preferiblemente lípidos naturales de un virus, una proteína de fusion viral, uno o más antígenos adicionales opcionales, así como coadyuvantes anfifílicos, como por ejemplo lipopéptidos, glicolípidos o péptidos, entre otros. Las composiciones farmacéuticas que comprenden dichas membranas virales reconstruidas.Vaccines directed against antigens, such as pathogen membrane proteins or tumor cells. Method for forming reconstructed viral membranes, with membrane fusion activity, which are membranes with two layers of lipids that preferably contain natural lipids of a virus, a viral fusion protein, one or more optional additional antigens, as well as amphiphilic adjuvants, such as for example lipopeptides, glycolipids or peptides, among others. The pharmaceutical compositions comprising said reconstructed viral membranes.

ARP040102097A 2003-06-19 2004-06-16 FUNCTIONAL RECONSTITUTED VIRAL MEMBRANES CONTAINING A COADYUVANT AR056245A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL0300450 2003-06-19

Publications (1)

Publication Number Publication Date
AR056245A1 true AR056245A1 (en) 2007-10-03

Family

ID=33550371

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102097A AR056245A1 (en) 2003-06-19 2004-06-16 FUNCTIONAL RECONSTITUTED VIRAL MEMBRANES CONTAINING A COADYUVANT

Country Status (20)

Country Link
US (1) US7618641B2 (en)
EP (2) EP1633395B1 (en)
JP (1) JP4685005B2 (en)
KR (1) KR101225199B1 (en)
CN (1) CN100556454C (en)
AR (1) AR056245A1 (en)
AU (1) AU2004246974B2 (en)
BR (1) BRPI0411519A (en)
CA (1) CA2527735C (en)
DK (2) DK1633395T3 (en)
ES (2) ES2390454T3 (en)
IL (1) IL172584A (en)
MX (1) MXPA05013929A (en)
NO (1) NO20055934L (en)
PL (2) PL1633395T3 (en)
RU (1) RU2348428C2 (en)
TW (1) TWI329130B (en)
UA (1) UA87269C2 (en)
WO (1) WO2004110486A1 (en)
ZA (1) ZA200509907B (en)

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WO2006078164A2 (en) 2005-01-18 2006-07-27 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Mycobacteria with mannose cap-deficient lipoarabinomannan
AR059972A1 (en) * 2006-03-22 2008-05-14 Solvay Pharm Bv VIROSOMAS INTRANASAL OR INHALATIONAL ADMINISTRATION
TWI397419B (en) * 2006-03-22 2013-06-01 Abbott Biologicals Bv Intranasal or inhalational administration of virosomes
US8535683B2 (en) 2006-03-22 2013-09-17 Abbott Biologicals B.V. Intranasal or inhalational administration of virosomes
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
EP2058002A1 (en) 2007-10-31 2009-05-13 Bestewil Holding B.V. Reconstituted respiratory syncytial virus membranes and use as respiratory syncytial virus vaccine
CA2750058C (en) 2009-02-06 2017-11-28 Mymetics Corporation Novel gp41 antigens
KR20110126636A (en) 2009-02-06 2011-11-23 마이메틱스 코포레이션 Splitting gp41
CA2792938C (en) 2010-03-23 2018-07-31 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
WO2011128720A1 (en) 2010-04-14 2011-10-20 Mymetics Corporation Trans-activator of transcription protein
EP2608802B1 (en) 2010-08-27 2017-02-22 Pantarhei Bioscience B.V. Immunotherapeutic method for treating prostate cancer
US20130259928A1 (en) * 2010-09-30 2013-10-03 Franvax S.R.L. Generation of virosome particles
US10806779B2 (en) 2013-07-02 2020-10-20 Janssen Vaccines & Prevention B.V. Method for preparing virosomes
NZ730357A (en) 2014-09-12 2021-12-24 Bestewil Holding Bv Methods for providing adjuvanted virosomes and adjuvanted virosomes obtainable thereby
WO2016039620A2 (en) 2014-09-12 2016-03-17 Bestewil Holding B.V. Respiratory syncytial virus virosomes
WO2016080830A2 (en) 2014-11-18 2016-05-26 Pantarhei Bioscience B.V. Immunotherapeutic method for treating pancreatic cancer
CN111511392A (en) 2017-10-31 2020-08-07 潘塔希生物科学股份有限公司 Immunotherapeutic method for the treatment and/or prevention of lung cancer
US20210317165A1 (en) 2018-09-03 2021-10-14 Laboratoire Hra-Pharma Zp3 fragments in immunotherapy of ovarian cancer
US11523988B2 (en) 2018-11-29 2022-12-13 Catalent U.K. Swindon Zydis Limited Oral dispersible vaccine comprising virosomes
US20200188511A1 (en) 2018-12-12 2020-06-18 Anergis S.A. Methods of improving efficacy of allergy vaccines
WO2021207303A1 (en) * 2020-04-07 2021-10-14 Alsatech, Inc. Immune stimulation against coronavirus infections
WO2023066923A1 (en) 2021-10-19 2023-04-27 Rahman Nafis Male contraception
WO2023237726A1 (en) 2022-06-10 2023-12-14 Pantarhei Oncology B.V. An intracellular tumor-specific variant of human zona pellucida glycoprotein 3 and nucleic acids coding therefor for use in the treatment of cancer
WO2024088138A1 (en) * 2022-10-25 2024-05-02 宁波明亦生物科技有限公司 Plasma membrane-permeabilized inactivated oral vaccine

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Also Published As

Publication number Publication date
CN100556454C (en) 2009-11-04
CA2527735A1 (en) 2004-12-23
ES2536689T3 (en) 2015-05-27
RU2006101394A (en) 2006-06-10
AU2004246974A1 (en) 2004-12-23
EP2368576B1 (en) 2015-02-25
BRPI0411519A (en) 2006-08-01
UA87269C2 (en) 2009-07-10
TWI329130B (en) 2010-08-21
RU2348428C2 (en) 2009-03-10
ES2390454T3 (en) 2012-11-13
KR20060030047A (en) 2006-04-07
US7618641B2 (en) 2009-11-17
JP4685005B2 (en) 2011-05-18
CA2527735C (en) 2014-12-16
EP2368576A3 (en) 2012-03-28
IL172584A0 (en) 2006-04-10
DK2368576T3 (en) 2015-05-18
US20060193873A1 (en) 2006-08-31
PL1633395T3 (en) 2012-12-31
JP2006527598A (en) 2006-12-07
TW200510538A (en) 2005-03-16
WO2004110486A1 (en) 2004-12-23
DK1633395T3 (en) 2012-10-29
EP1633395B1 (en) 2012-08-01
PL2368576T3 (en) 2015-12-31
AU2004246974B2 (en) 2010-05-06
IL172584A (en) 2010-11-30
EP2368576A2 (en) 2011-09-28
MXPA05013929A (en) 2006-03-08
NO20055934L (en) 2006-03-20
EP1633395A1 (en) 2006-03-15
ZA200509907B (en) 2006-11-29
KR101225199B1 (en) 2013-01-23
CN1805754A (en) 2006-07-19

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