AR055642A1 - USE OF MASLINIC ACID AS AN ANTIPARASITARY AGAINST PROTOZOOS OF PHYLLUM APICOMPLEX - Google Patents
USE OF MASLINIC ACID AS AN ANTIPARASITARY AGAINST PROTOZOOS OF PHYLLUM APICOMPLEXInfo
- Publication number
- AR055642A1 AR055642A1 ARP060104104A ARP060104104A AR055642A1 AR 055642 A1 AR055642 A1 AR 055642A1 AR P060104104 A ARP060104104 A AR P060104104A AR P060104104 A ARP060104104 A AR P060104104A AR 055642 A1 AR055642 A1 AR 055642A1
- Authority
- AR
- Argentina
- Prior art keywords
- phyllum
- maslinic acid
- protozoos
- apicomplex
- antiparasitary
- Prior art date
Links
- MDZKJHQSJHYOHJ-UHFFFAOYSA-N crataegolic acid Natural products C1C(O)C(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MDZKJHQSJHYOHJ-UHFFFAOYSA-N 0.000 title abstract 3
- MDZKJHQSJHYOHJ-LLICELPBSA-N maslinic acid Chemical compound C1[C@@H](O)[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MDZKJHQSJHYOHJ-LLICELPBSA-N 0.000 title abstract 3
- 241000224482 Apicomplexa Species 0.000 abstract 2
- 241000223836 Babesia Species 0.000 abstract 1
- 241000179197 Cyclospora Species 0.000 abstract 1
- 241000223924 Eimeria Species 0.000 abstract 1
- 241000567229 Isospora Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241001147660 Neospora Species 0.000 abstract 1
- 208000030852 Parasitic disease Diseases 0.000 abstract 1
- 241000224016 Plasmodium Species 0.000 abstract 1
- 241000223996 Toxoplasma Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002141 anti-parasite Effects 0.000 abstract 1
- 239000003096 antiparasitic agent Substances 0.000 abstract 1
- 201000008680 babesiosis Diseases 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003001 serine protease inhibitor Substances 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Utilizacion de ácido maslínico como antiparasitario frente a Protozoos del Phyllum Apicomplexa. El ácido 2-alfa,3-betadihidroxi-28-carboxiolean-12-eno (ácido maslínico), sus sales y derivados se utilizan como inhibidores de serin-proteasas para la obtencion de preparados destinados al tratamiento y prevencion de parasitosis causadas en humanos y animales por las especies del Phyllum Apicomplexa: Eimeria, Toxoplasma, Neospora, Cyclospora, Isospora, Besnoisia, Babesia y Plasmodium.Use of maslinic acid as an antiparasitic against Protozoa of Phyllum Apicomplexa. The 2-alpha, 3-betadihydroxy-28-carboxylean-12-ene (maslinic acid) acid, its salts and derivatives are used as serine protease inhibitors to obtain preparations for the treatment and prevention of parasitosis caused in humans and animals by the species of Phyllum Apicomplexa: Eimeria, Toxoplasma, Neospora, Cyclospora, Isospora, Besnoisia, Babesia and Plasmodium.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200502349A ES2282027B1 (en) | 2005-09-20 | 2005-09-20 | USE OF MASLINIC ACID AS ANTIPARASITARY AGAINST PROTOZOOS OF THE PHYLLUM APICOMPLEXA. |
Publications (1)
Publication Number | Publication Date |
---|---|
AR055642A1 true AR055642A1 (en) | 2007-08-29 |
Family
ID=37889164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060104104A AR055642A1 (en) | 2005-09-20 | 2006-09-19 | USE OF MASLINIC ACID AS AN ANTIPARASITARY AGAINST PROTOZOOS OF PHYLLUM APICOMPLEX |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR055642A1 (en) |
ES (1) | ES2282027B1 (en) |
WO (1) | WO2007034009A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101619088B (en) * | 2009-08-04 | 2012-07-04 | 上海朴颐化学科技有限公司 | Maslinic acid derivative as well as preparation and application thereof |
ES2392522A1 (en) * | 2011-05-28 | 2012-12-11 | Universidad De La Laguna | Composition for the maintenance of contact lenses that results effective against acanthamoeba ssp. (Machine-translation by Google Translate, not legally binding) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888518A (en) * | 1995-10-06 | 1999-03-30 | Beretich, Sr.; Guy R. | Method for preventing and treating coccidiosis |
ES2131467B1 (en) * | 1997-05-12 | 2000-04-01 | Univ Granada | USE OF MASLINIC ACID AS A SERIN-PROTEASE INHIBITOR FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENE CRYPTOSPORIDIUM. |
EP1578429A4 (en) * | 2002-05-22 | 2006-12-06 | Smithkline Beecham Corp | Protease inhibitors |
-
2005
- 2005-09-20 ES ES200502349A patent/ES2282027B1/en active Active
-
2006
- 2006-09-04 WO PCT/ES2006/000500 patent/WO2007034009A2/en active Application Filing
- 2006-09-19 AR ARP060104104A patent/AR055642A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2282027B1 (en) | 2008-10-01 |
WO2007034009A2 (en) | 2007-03-29 |
ES2282027A1 (en) | 2007-10-01 |
WO2007034009A3 (en) | 2007-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |