AR053121A1 - RACEMIC AND OPTICALLY ACTIVE ACID DERIVATIVES 4-CHLORINE-3- (5-CHLORINE-3-RENT-2-OXO-2,3-DIHIDRO-1H-INDOL-3-IL) BENZOIC - Google Patents

RACEMIC AND OPTICALLY ACTIVE ACID DERIVATIVES 4-CHLORINE-3- (5-CHLORINE-3-RENT-2-OXO-2,3-DIHIDRO-1H-INDOL-3-IL) BENZOIC

Info

Publication number
AR053121A1
AR053121A1 ARP060100356A ARP060100356A AR053121A1 AR 053121 A1 AR053121 A1 AR 053121A1 AR P060100356 A ARP060100356 A AR P060100356A AR P060100356 A ARP060100356 A AR P060100356A AR 053121 A1 AR053121 A1 AR 053121A1
Authority
AR
Argentina
Prior art keywords
chlorine
optically active
racemic
oxo
benzoic
Prior art date
Application number
ARP060100356A
Other languages
Spanish (es)
Inventor
Gyorgyne Szvoboda
Csutor Andrea Santane
Csaba Gonczi
Istvan Hermecz
Lajos Nagy
Maria Kelemenne Miko
Erika Filep
Tiborne Szomor
Lodc Foulon
Gerard Valette
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of AR053121A1 publication Critical patent/AR053121A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)

Abstract

Derivados opticamente activos del ácido 4-cloro-3-(5-cloro-3-alquil-2-oxo-2,3-dihidro-1H-indol-3-il) benzoico de formula general (1) caracterizados porque R representa hidrogeno o un grupo alquilo C1-4 de cadena recta o ramificada, y R2 representa un grupo alquilo C1-4 de cadena recta o ramificada, y sus sales formadas con bases orgánicas o inorgánicas. Método de preparacion de compuestos racémicos y opticamente activos de la formula general (1)Optically active derivatives of 4-chloro-3- (5-chloro-3-alkyl-2-oxo-2,3-dihydro-1H-indole-3-yl) benzoic acid of general formula (1) characterized in that R represents hydrogen or a straight or branched C1-4 alkyl group, and R2 represents a straight or branched C1-4 alkyl group, and their salts formed with organic or inorganic bases. Method of preparation of racemic and optically active compounds of the general formula (1)

ARP060100356A 2005-02-02 2006-02-01 RACEMIC AND OPTICALLY ACTIVE ACID DERIVATIVES 4-CHLORINE-3- (5-CHLORINE-3-RENT-2-OXO-2,3-DIHIDRO-1H-INDOL-3-IL) BENZOIC AR053121A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0500167A HUP0500167A2 (en) 2005-02-02 2005-02-02 Optically active 4-chloro-3-(5-chloro-3-alkyl-2-oxo-2,3-dihydro-1h-indol-3-yl)benzoic acid derivatives and process for producing them

Publications (1)

Publication Number Publication Date
AR053121A1 true AR053121A1 (en) 2007-04-25

Family

ID=89985791

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100356A AR053121A1 (en) 2005-02-02 2006-02-01 RACEMIC AND OPTICALLY ACTIVE ACID DERIVATIVES 4-CHLORINE-3- (5-CHLORINE-3-RENT-2-OXO-2,3-DIHIDRO-1H-INDOL-3-IL) BENZOIC

Country Status (5)

Country Link
AR (1) AR053121A1 (en)
HU (1) HUP0500167A2 (en)
TW (1) TW200700385A (en)
UY (1) UY29359A1 (en)
WO (1) WO2006082453A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565483A (en) * 1995-06-07 1996-10-15 Bristol-Myers Squibb Company 3-substituted oxindole derivatives as potassium channel modulators
US6673790B1 (en) * 2000-04-03 2004-01-06 Sanofi-Synthelabo Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands

Also Published As

Publication number Publication date
TW200700385A (en) 2007-01-01
HU0500167D0 (en) 2005-04-28
UY29359A1 (en) 2006-08-31
HUP0500167A2 (en) 2007-03-28
WO2006082453A1 (en) 2006-08-10

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AR053121A1 (en) RACEMIC AND OPTICALLY ACTIVE ACID DERIVATIVES 4-CHLORINE-3- (5-CHLORINE-3-RENT-2-OXO-2,3-DIHIDRO-1H-INDOL-3-IL) BENZOIC

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FA Abandonment or withdrawal