AR051324A1 - PROCEDURE FOR THE PREPARATION OF MONOSUSTITUTED PIPERAZINE DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF MONOSUSTITUTED PIPERAZINE DERIVATIVES

Info

Publication number
AR051324A1
AR051324A1 ARP050104249A ARP050104249A AR051324A1 AR 051324 A1 AR051324 A1 AR 051324A1 AR P050104249 A ARP050104249 A AR P050104249A AR P050104249 A ARP050104249 A AR P050104249A AR 051324 A1 AR051324 A1 AR 051324A1
Authority
AR
Argentina
Prior art keywords
preparation
monosustituted
procedure
piperazine derivatives
piperazine
Prior art date
Application number
ARP050104249A
Other languages
Spanish (es)
Inventor
Andreas Bathe
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR051324A1 publication Critical patent/AR051324A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente se refiere a un procedimiento para la preparacion de alquil- y aralquilpiperazinas monosustituidas por aminolisis de los correspondientes alquil- o aralquilmesilatos con piperazina en solventes ácidos acuosos.This refers to a process for the preparation of alkyl- and aralkylpiperazines monosubstituted by aminolysis of the corresponding alkyl- or aralkylmesylates with piperazine in aqueous acid solvents.

ARP050104249A 2004-10-11 2005-10-11 PROCEDURE FOR THE PREPARATION OF MONOSUSTITUTED PIPERAZINE DERIVATIVES AR051324A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE200410049728 DE102004049728A1 (en) 2004-10-11 2004-10-11 Process for the preparation of monosubstituted piperazine derivatives

Publications (1)

Publication Number Publication Date
AR051324A1 true AR051324A1 (en) 2007-01-03

Family

ID=35229888

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050104249A AR051324A1 (en) 2004-10-11 2005-10-11 PROCEDURE FOR THE PREPARATION OF MONOSUSTITUTED PIPERAZINE DERIVATIVES

Country Status (3)

Country Link
AR (1) AR051324A1 (en)
DE (1) DE102004049728A1 (en)
WO (1) WO2006039974A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5838628B2 (en) * 2011-07-25 2016-01-06 東ソー株式会社 Process for producing N-alkylpiperazines
CZ2012498A3 (en) * 2011-12-20 2014-06-11 Masarykova Univerzita Process of piperazine direct mono-N-substitution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB840358A (en) * 1957-10-11 1960-07-06 British Drug Houses Ltd Improvements in or relating to the manufacture of n-mono-substituted piperazines
CS196893B1 (en) * 1977-12-22 1980-04-30 Miroslav Protiva 3-fluor-10-piperazino-8-substituted 10,11-dihydro-dibenzothiepines
KR970703324A (en) * 1994-05-18 1997-07-03 쇼오다 오사무 Novel pyrimidine derivatives (NOVEL PYRIMIDINE DERIVATIVE)

Also Published As

Publication number Publication date
DE102004049728A1 (en) 2006-04-13
WO2006039974A1 (en) 2006-04-20

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal