AR048000A1 - SUBSTANTIALLY LINEAR EFERVESCENT ORAL DOSAGE FORM OF FENTANIL AND METHODS OF ADMINISTRATION - Google Patents
SUBSTANTIALLY LINEAR EFERVESCENT ORAL DOSAGE FORM OF FENTANIL AND METHODS OF ADMINISTRATIONInfo
- Publication number
- AR048000A1 AR048000A1 ARP050100912A AR048000A1 AR 048000 A1 AR048000 A1 AR 048000A1 AR P050100912 A ARP050100912 A AR P050100912A AR 048000 A1 AR048000 A1 AR 048000A1
- Authority
- AR
- Argentina
- Prior art keywords
- dosage form
- fentanyl
- administration
- weight
- methods
- Prior art date
Links
Classifications
-
- Y02W90/11—
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Formas de dosificacion que contienen fentanilo y métodos de uso de las mismas. Estas formas de dosificacion incluyen substancialmente menos fentanilo por peso que las formulaciones orales conocidas y presentan ventajas en términos de costos y de efectos colaterales. Estas formas de dosificacion están destinadas a la administracion oral de fentanilo a través de la mucosa oral. Reivindicacion 1: Una forma de dosificacion, caracterizada porque comprende: entre aproximadamente 100 y aproximadamente 800 microgramos de fentanilo, calculado como base libre de fentanilo o una cantidad equivalente de una sal del mismo, un par para efervescencia en una cantidad que comprende entre aproximadamente 5 y aproximadamente 85% en peso de la forma de dosificacion, una sustancia para ajustar el pH en una cantidad que comprende entre aproximadamente 0,5 y aproximadamente 25% en peso de la forma de dosificacion y un almidon glicolato en una cantidad que comprende entre aproximadamente 0,25 y aproximadamente 20% en peso de la forma de dosificacion, siendo dicha forma de dosificacion adecuada para la distribucion de dicho fentanilo a través de la mucosa oral de un paciente mediante administracion bucal, gingival o sublingual.Dosage forms containing fentanyl and methods of use thereof. These dosage forms include substantially less fentanyl by weight than known oral formulations and have advantages in terms of costs and side effects. These dosage forms are intended for oral administration of fentanyl through the oral mucosa. Claim 1: A dosage form, characterized in that it comprises: between about 100 and about 800 micrograms of fentanyl, calculated as fentanyl free base or an equivalent amount of a salt thereof, an effervescence pair in an amount comprising between about 5 and about 85% by weight of the dosage form, a substance for adjusting the pH in an amount comprising between about 0.5 and about 25% by weight of the dosage form and a starch glycolate in an amount comprising between about 0.25 and about 20% by weight of the dosage form, said dosage form being suitable for the distribution of said fentanyl through the oral mucosa of a patient by oral, gingival or sublingual administration.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61566504P | 2004-10-04 | 2004-10-04 | |
| US11/026,327 US20050142197A1 (en) | 2003-12-31 | 2004-12-30 | Generally linear effervescent oral fentanyl dosage form and methods of administering |
| US11/026,132 US7862832B2 (en) | 2003-12-31 | 2004-12-30 | Generally linear effervescent oral fentanyl dosage form and methods of administering |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR048000A1 true AR048000A1 (en) | 2006-03-15 |
Family
ID=36607219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050100912 AR048000A1 (en) | 2004-10-04 | 2005-03-09 | SUBSTANTIALLY LINEAR EFERVESCENT ORAL DOSAGE FORM OF FENTANIL AND METHODS OF ADMINISTRATION |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR048000A1 (en) |
-
2005
- 2005-03-09 AR ARP050100912 patent/AR048000A1/en not_active Application Discontinuation
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