AR043088A1 - PHARMACEUTICAL COMPOSITION AND USE OF SUCH COMPOSITION AND OF AN ACTIVE INGREDIENT THAT IS METABOLIZED BY 5-ALFA-REDUCTASE IN THE PREPARATION OF A TRANSMUCOSAL ADMINISTRATION MEDICINAL PRODUCT - Google Patents

PHARMACEUTICAL COMPOSITION AND USE OF SUCH COMPOSITION AND OF AN ACTIVE INGREDIENT THAT IS METABOLIZED BY 5-ALFA-REDUCTASE IN THE PREPARATION OF A TRANSMUCOSAL ADMINISTRATION MEDICINAL PRODUCT

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Publication number
AR043088A1
AR043088A1 ARP000103113A AR043088A1 AR 043088 A1 AR043088 A1 AR 043088A1 AR P000103113 A ARP000103113 A AR P000103113A AR 043088 A1 AR043088 A1 AR 043088A1
Authority
AR
Argentina
Prior art keywords
composition
active ingredient
metabolized
reductase
transmucosal administration
Prior art date
Application number
Other languages
Spanish (es)
Inventor
William J Bologna
Howard L Levine
Dominique Ziegler
Original Assignee
Columbia Laboratoires Bermuda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40943521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR043088(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/379,310 external-priority patent/US6248358B1/en
Application filed by Columbia Laboratoires Bermuda filed Critical Columbia Laboratoires Bermuda
Publication of AR043088A1 publication Critical patent/AR043088A1/en

Links

Abstract

Composición farmacéutica que comprende una cantidad efectiva de un ingrediente activo que es metabolizado por la 5alfa-reductasa, un polímero policarboxílico entrecruzado, hinchable en agua, y un polímero soluble en agua. Esta composición esta formulada para su uso en la liberación prolongada y controlada de los ingredientes activos en el torrente sanguíneo de un mamífero, a través de una superficie de mucosa de dicho mamífero. Uso de dicha composición y de dicho ingrediente activo en la fabricación de un medicamento de administración transmucosal a un mamífero como una composición bioadhesiva de hidratación progresiva.Pharmaceutical composition comprising an effective amount of an active ingredient that is metabolized by 5alpha reductase, a crosslinked polycarboxylic polymer, water swellable, and a water soluble polymer. This composition is formulated for use in the prolonged and controlled release of the active ingredients in the bloodstream of a mammal, through a mucosal surface of said mammal. Use of said composition and said active ingredient in the manufacture of a medicament for transmucosal administration to a mammal as a bioadhesive composition of progressive hydration.

ARP000103113 1999-08-23 2000-06-22 PHARMACEUTICAL COMPOSITION AND USE OF SUCH COMPOSITION AND OF AN ACTIVE INGREDIENT THAT IS METABOLIZED BY 5-ALFA-REDUCTASE IN THE PREPARATION OF A TRANSMUCOSAL ADMINISTRATION MEDICINAL PRODUCT AR043088A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/379,310 US6248358B1 (en) 1998-08-25 1999-08-23 Bioadhesive progressive hydration tablets and methods of making and using the same
US59607300A 2000-06-16 2000-06-16

Publications (1)

Publication Number Publication Date
AR043088A1 true AR043088A1 (en) 2005-07-20

Family

ID=40943521

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000103113 AR043088A1 (en) 1999-08-23 2000-06-22 PHARMACEUTICAL COMPOSITION AND USE OF SUCH COMPOSITION AND OF AN ACTIVE INGREDIENT THAT IS METABOLIZED BY 5-ALFA-REDUCTASE IN THE PREPARATION OF A TRANSMUCOSAL ADMINISTRATION MEDICINAL PRODUCT

Country Status (3)

Country Link
AR (1) AR043088A1 (en)
CO (1) CO5160244A1 (en)
PE (1) PE20010519A1 (en)

Also Published As

Publication number Publication date
CO5160244A1 (en) 2002-05-30
PE20010519A1 (en) 2001-05-17

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