AR042822A1 - CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE - Google Patents
CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGEInfo
- Publication number
- AR042822A1 AR042822A1 ARP030104847A AR042822A1 AR 042822 A1 AR042822 A1 AR 042822A1 AR P030104847 A ARP030104847 A AR P030104847A AR 042822 A1 AR042822 A1 AR 042822A1
- Authority
- AR
- Argentina
- Prior art keywords
- core
- drug
- coating composition
- pharmaces
- enteric
- Prior art date
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- Medicinal Preparation (AREA)
Abstract
Sistema de administración controlada de fármacos de retención gástrica que comprende: (a) un núcleo de liberación controlada que comprende un fármaco, un polímero altamente expansible y un agente generador de gas, en donde dicho núcleo es capaz de expandirse y lograr flotación rápidamente mientras mantiene su integridad física en fluidos gastrointestinales pro períodos prolongados, y (b) una composición de recubrimiento que se libera rápidamente, que comprende el mismo fármaco que el núcleo y excipientes farmacéuticamente aceptables, en donde la composición de recubrimiento rodea el núcleo y excipientes farmacéuticamente aceptables, en donde la composición de recubrimiento rodea el núcleo de modo tal que el sistema provee una liberación bifásica del fármaco baclofeno, entre otros, en fluidos gastrointestinales.Controlled gastric retention drug delivery system comprising: (a) a controlled release core comprising a drug, a highly expandable polymer and a gas generating agent, wherein said core is capable of rapidly expanding and float while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coating composition, comprising the same drug as the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug baclofen, among others, in gastrointestinal fluids.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP030104847 AR042822A1 (en) | 2003-12-29 | 2003-12-29 | CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP030104847 AR042822A1 (en) | 2003-12-29 | 2003-12-29 | CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE |
Publications (1)
Publication Number | Publication Date |
---|---|
AR042822A1 true AR042822A1 (en) | 2005-07-06 |
Family
ID=42777919
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP030104847 AR042822A1 (en) | 2003-12-29 | 2003-12-29 | CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE |
Country Status (1)
Country | Link |
---|---|
AR (1) | AR042822A1 (en) |
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2003
- 2003-12-29 AR ARP030104847 patent/AR042822A1/en unknown
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