AR042822A1 - CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE - Google Patents

CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE

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Publication number
AR042822A1
AR042822A1 ARP030104847A AR042822A1 AR 042822 A1 AR042822 A1 AR 042822A1 AR P030104847 A ARP030104847 A AR P030104847A AR 042822 A1 AR042822 A1 AR 042822A1
Authority
AR
Argentina
Prior art keywords
core
drug
coating composition
pharmaces
enteric
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Kamlesh Mohanlal Dudhara
Nitin Bhalachandra Dharmadhikari
Vaishali Vijay Dhavse
Original Assignee
Sun Pharmaceutical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd filed Critical Sun Pharmaceutical Ind Ltd
Priority to ARP030104847 priority Critical patent/AR042822A1/en
Publication of AR042822A1 publication Critical patent/AR042822A1/en

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Abstract

Sistema de administración controlada de fármacos de retención gástrica que comprende: (a) un núcleo de liberación controlada que comprende un fármaco, un polímero altamente expansible y un agente generador de gas, en donde dicho núcleo es capaz de expandirse y lograr flotación rápidamente mientras mantiene su integridad física en fluidos gastrointestinales pro períodos prolongados, y (b) una composición de recubrimiento que se libera rápidamente, que comprende el mismo fármaco que el núcleo y excipientes farmacéuticamente aceptables, en donde la composición de recubrimiento rodea el núcleo y excipientes farmacéuticamente aceptables, en donde la composición de recubrimiento rodea el núcleo de modo tal que el sistema provee una liberación bifásica del fármaco baclofeno, entre otros, en fluidos gastrointestinales.Controlled gastric retention drug delivery system comprising: (a) a controlled release core comprising a drug, a highly expandable polymer and a gas generating agent, wherein said core is capable of rapidly expanding and float while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coating composition, comprising the same drug as the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug baclofen, among others, in gastrointestinal fluids.

ARP030104847 2003-12-29 2003-12-29 CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE AR042822A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP030104847 AR042822A1 (en) 2003-12-29 2003-12-29 CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP030104847 AR042822A1 (en) 2003-12-29 2003-12-29 CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE

Publications (1)

Publication Number Publication Date
AR042822A1 true AR042822A1 (en) 2005-07-06

Family

ID=42777919

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030104847 AR042822A1 (en) 2003-12-29 2003-12-29 CONTROLLED ADMINISTRATION SYSTEM OF GASTRIC RETAINING PHARMACES WITH ENTERIC COVERAGE

Country Status (1)

Country Link
AR (1) AR042822A1 (en)

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