AR035466A1 - Estructura cristalina de yqej y usos de la misma - Google Patents

Estructura cristalina de yqej y usos de la misma

Info

Publication number
AR035466A1
AR035466A1 ARP020103072A ARP020103072A AR035466A1 AR 035466 A1 AR035466 A1 AR 035466A1 AR P020103072 A ARP020103072 A AR P020103072A AR P020103072 A ARP020103072 A AR P020103072A AR 035466 A1 AR035466 A1 AR 035466A1
Authority
AR
Argentina
Prior art keywords
yqej
crystal structure
same
agents
crystallized
Prior art date
Application number
ARP020103072A
Other languages
English (en)
Original Assignee
Millennium Pharm Inc
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Wyeth Corp filed Critical Millennium Pharm Inc
Publication of AR035466A1 publication Critical patent/AR035466A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N25/00—Investigating or analyzing materials by the use of thermal means
    • G01N25/14—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
    • G01N25/147—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation by cristallisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50—Molecular design, e.g. of drugs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Computing Systems (AREA)
  • General Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Estructura cristalina de yqeJ y uso de esta estructura en métodos de diseno racional de fármacos para identificar agentes capaces de interactuar con los sitios activos de yqeJ. Dichos agentes pueden ser de utilidad como agentes antibacterianos. Reivindicación 1 Una yqeJ cristalizada, caracterizada porque tiene cuatro moléculas de yqeJ en la unidad asimétrica.
ARP020103072A 2001-08-17 2002-08-14 Estructura cristalina de yqej y usos de la misma AR035466A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31315301P 2001-08-17 2001-08-17
US34061301P 2001-12-07 2001-12-07

Publications (1)

Publication Number Publication Date
AR035466A1 true AR035466A1 (es) 2004-05-26

Family

ID=27616575

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020103072A AR035466A1 (es) 2001-08-17 2002-08-14 Estructura cristalina de yqej y usos de la misma

Country Status (4)

Country Link
US (1) US7155346B2 (es)
AR (1) AR035466A1 (es)
AU (1) AU2002365245A1 (es)
WO (1) WO2003062371A2 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130105A (en) * 1990-10-23 1992-07-14 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Protein crystal growth tray assembly
US6664074B2 (en) * 2001-02-23 2003-12-16 Millennium Pharmaceuticals, Inc. Use of yacM and yqeJ, essential bacterial genes and polypeptides and their use

Also Published As

Publication number Publication date
US7155346B2 (en) 2006-12-26
US20030124699A1 (en) 2003-07-03
AU2002365245A8 (en) 2006-11-02
AU2002365245A1 (en) 2003-09-02
WO2003062371A3 (en) 2006-03-23
WO2003062371A2 (en) 2003-07-31

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Legal Events

Date Code Title Description
FC Refusal
FA Abandonment or withdrawal