AR034489A1 - A DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION. - Google Patents

A DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION.

Info

Publication number
AR034489A1
AR034489A1 ARP020102240A ARP020102240A AR034489A1 AR 034489 A1 AR034489 A1 AR 034489A1 AR P020102240 A ARP020102240 A AR P020102240A AR P020102240 A ARP020102240 A AR P020102240A AR 034489 A1 AR034489 A1 AR 034489A1
Authority
AR
Argentina
Prior art keywords
dry powder
inhalation system
powder inhalation
transpulmonary administration
sec
Prior art date
Application number
ARP020102240A
Other languages
Spanish (es)
Inventor
Chikamasa Yamashita
Shigeru Ibaragi
Yuichiro Fukunaga
Akitsuna Akagi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of AR034489A1 publication Critical patent/AR034489A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un nuevo sistema de inhalación de polvo seco adecuado para la administración transpulmonar. El sistema de inhalación de polvo seco de la presente está caracterizado porque usa una combinación de: un recipiente que aloja una composición liofilizada que contiene una sola dosis de un ingrediente activo, y tiene: (1) una forma tipo torta, no en polvo; (2) un índice de desintegración de 0,015 o más, y (3) una propiedad de convertirse en finas partículas que tienen un diámetro de partícula promedio de 10 micrones o menos o una fracción de partículas finas de 10% o más después de recibir un impacto de aire que tiene una velocidad de aire de por lo menos 1 m/seg y un caudal de aire de por lo menos 17 ml/seg; y un dispositivo que comprende elementos capaces de aplicar dicho impacto de aire a la composición liofilizada en dicho recipiente, y elementos para descargar la composición liofilizada en forma de polvo que ha sido convertida en partículas finas.A new dry powder inhalation system suitable for transpulmonary administration. The dry powder inhalation system herein is characterized in that it uses a combination of: a container that houses a lyophilized composition containing a single dose of an active ingredient, and has: (1) a cake-like, non-powdered form; (2) a decay index of 0.015 or more, and (3) a property of becoming fine particles having an average particle diameter of 10 microns or less or a fine particle fraction of 10% or more after receiving a air impact having an air velocity of at least 1 m / sec and an air flow rate of at least 17 ml / sec; and a device comprising elements capable of applying said air impact to the lyophilized composition in said container, and elements for discharging the lyophilized powder composition that has been converted into fine particles.

ARP020102240A 2001-06-15 2002-06-14 A DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION. AR034489A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001182504 2001-06-15
JP2001400871 2001-12-28
JP2002111131 2002-04-12

Publications (1)

Publication Number Publication Date
AR034489A1 true AR034489A1 (en) 2004-02-25

Family

ID=40707472

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102240A AR034489A1 (en) 2001-06-15 2002-06-14 A DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION.

Country Status (9)

Country Link
JP (1) JP4258647B2 (en)
KR (1) KR100815216B1 (en)
AR (1) AR034489A1 (en)
HK (2) HK1066748A1 (en)
IL (1) IL159080A (en)
MY (1) MY136601A (en)
NO (1) NO20131597L (en)
PE (1) PE20030189A1 (en)
ZA (1) ZA200309550B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006025884A1 (en) * 2006-06-02 2007-12-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Adapter with a connector for a nebulizer
EP2043717A1 (en) * 2006-07-14 2009-04-08 Astra Zeneca AB Inhalation system and delivery device for the administration of a drug in the form of dry powder
EP2082762A1 (en) * 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhaler
KR102077790B1 (en) * 2018-04-18 2020-02-14 라이프리버 주식회사 Powder spray device in which the spray amount is controllable
TWI812509B (en) * 2022-10-17 2023-08-11 國立成功大學 Functional powder delivery device and system thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0464878A (en) * 1990-07-04 1992-02-28 Mitsubishi Heavy Ind Ltd Absorber for absorption refrigerating machine
JPH06186141A (en) * 1992-12-16 1994-07-08 Hitachi Ltd Remaining stress prediction method
TW403653B (en) * 1995-12-25 2000-09-01 Otsuka Pharma Co Ltd Dry compositions

Also Published As

Publication number Publication date
NO20131597L (en) 2004-02-12
HK1127567A1 (en) 2009-10-02
JP2004329962A (en) 2004-11-25
ZA200309550B (en) 2005-02-23
HK1066748A1 (en) 2005-04-01
KR100815216B1 (en) 2008-03-19
KR20040069978A (en) 2004-08-06
PE20030189A1 (en) 2003-03-12
MY136601A (en) 2008-10-31
JP4258647B2 (en) 2009-04-30
IL159080A (en) 2009-02-11

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Legal Events

Date Code Title Description
FG Grant, registration