AR030999A1 - ANTIBACTERIAL AGENTS CONTAINING CETOLIDE - Google Patents
ANTIBACTERIAL AGENTS CONTAINING CETOLIDEInfo
- Publication number
- AR030999A1 AR030999A1 ARP010104875A ARP010104875A AR030999A1 AR 030999 A1 AR030999 A1 AR 030999A1 AR P010104875 A ARP010104875 A AR P010104875A AR P010104875 A ARP010104875 A AR P010104875A AR 030999 A1 AR030999 A1 AR 030999A1
- Authority
- AR
- Argentina
- Prior art keywords
- heterocycle
- aryl
- alkynyl
- alkyl
- alkenyl
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Incluye compuestos de la formula (1) en la cual: X es hidrogreno o haluro; R2 es hidrogeno, acilo o un grupo protector hidroxi; R6 es hidrogeno, hidroxilo u -ORa en la cual Ra es un grupo funcional sustituido o no sustituido seleccionado del grupo que consiste de alquilo C1-10, alquenilo C2-10, alquinilo C2-10, arilo, heterociclo, aril(C1-10)alquilo, aril(C2-10)alquenilo, aril(C2-10)alquinilo, heterociclo(C1-10)alquilo, heterociclo(C2-10)alquenilo y heterociclo(C2-10)alquinilo; R13 es hidrogeno o un grupo funcional sustituido o no sustituido en el cual el grupo funcional se selecciona del grupo que consiste de metilo, alquilo C3-10, alquenilo C2-10, alquinilo C2-10, arilo, heterociclo, aril(C1-10)alquilo, aril(C2-10)alquenilo y heterociclo(C2-10)alquinilo; y R es hidrogeno o un grupo funcional sustituido o no sustituido en el cual el grupo que consiste de alquilo C1-10, alquenilo C2-10, alquinilo C2-10, arilo, heterociclo, aril(C1-10)alquilo, aril(C2-10)alquenilo, aril(C2-10)alquinilo, heterociclo(C1-10)alquilo, heterociclo(C2-10)alquenilo y heterociclo(C2-10)alquinilo; y sus sales, ésteres y prodrogas aceptables para uso farmacéutico. Estos compuestos poseen actividad anti-infecciosa y son utiles para el tratamiento de infecciones bacterianas o protozooicas.It includes compounds of the formula (1) in which: X is hydrogrene or halide; R2 is hydrogen, acyl or a hydroxy protecting group; R6 is hydrogen, hydroxyl or -ORa in which Ra is a substituted or unsubstituted functional group selected from the group consisting of C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heterocycle, aryl (C1-10 ) alkyl, (C2-10) alkenyl, aryl (C2-10) alkynyl, heterocycle (C1-10) alkyl, heterocycle (C2-10) alkenyl and heterocycle (C2-10) alkynyl; R13 is hydrogen or a substituted or unsubstituted functional group in which the functional group is selected from the group consisting of methyl, C3-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heterocycle, aryl (C1-10 ) alkyl, (C2-10) aryl, and (C2-10) alkynyl heterocycle; and R is hydrogen or a substituted or unsubstituted functional group in which the group consisting of C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heterocycle, aryl (C1-10) alkyl, aryl (C2 -10) alkenyl, aryl (C2-10) alkynyl, heterocycle (C1-10) alkyl, heterocycle (C2-10) alkenyl and heterocycle (C2-10) alkynyl; and its salts, esters and prodrugs acceptable for pharmaceutical use. These compounds possess anti-infectious activity and are useful for the treatment of bacterial or protozoan infections.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP010104875A AR030999A1 (en) | 2001-10-17 | 2001-10-17 | ANTIBACTERIAL AGENTS CONTAINING CETOLIDE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP010104875A AR030999A1 (en) | 2001-10-17 | 2001-10-17 | ANTIBACTERIAL AGENTS CONTAINING CETOLIDE |
Publications (1)
Publication Number | Publication Date |
---|---|
AR030999A1 true AR030999A1 (en) | 2003-09-03 |
Family
ID=37515965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010104875A AR030999A1 (en) | 2001-10-17 | 2001-10-17 | ANTIBACTERIAL AGENTS CONTAINING CETOLIDE |
Country Status (1)
Country | Link |
---|---|
AR (1) | AR030999A1 (en) |
-
2001
- 2001-10-17 AR ARP010104875A patent/AR030999A1/en unknown
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