AR030018A1 -
DERIVATIVES OF BENZO (D) (1,3) OXAZIN-2-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THE USE OF THE SAME TO PREPARE MEDICATIONS AS PROGESTERONE RECEPTING MODULATORS
- Google Patents
DERIVATIVES OF BENZO (D) (1,3) OXAZIN-2-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THE USE OF THE SAME TO PREPARE MEDICATIONS AS PROGESTERONE RECEPTING MODULATORS
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Application filed by Wyeth Corp, Ligand Pharm IncfiledCriticalWyeth Corp
Publication of AR030018A1publicationCriticalpatent/AR030018A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Un derivado benzo[d][1,3]oxazin-2-ona o una sal farmacéuticamente aceptable de la misma de formula general (1) en donde R1, R2, R3, R4 y R5 tiene el significado dado en la memoria descriptiva, composiciones farmacéuticas que las contienen y el uso de los mismos para preparar un medicamento para inducir la contracepcion, terapia de reemplazo hormonal, fibroides miometrial uterina, endometriosis, hipertrofia prostática benigna; carcinomas y adenocarcinomas del endometrio, ovario, pecho, colon, prostata, pituitaria, meningioma y para sincronizar el estro de un mamífero.A benzo [d] [1,3] oxazin-2-one derivative or a pharmaceutically acceptable salt thereof of general formula (1) wherein R1, R2, R3, R4 and R5 has the meaning given in the specification, pharmaceutical compositions containing them and the use thereof to prepare a medicament for inducing contraception, hormone replacement therapy, uterine myometrial fibroids, endometriosis, benign prostatic hypertrophy; carcinomas and adenocarcinomas of the endometrium, ovary, chest, colon, prostate, pituitary, meningioma and to synchronize the estrus of a mammal.
ARP000102155A1999-05-042000-05-04
DERIVATIVES OF BENZO (D) (1,3) OXAZIN-2-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THE USE OF THE SAME TO PREPARE MEDICATIONS AS PROGESTERONE RECEPTING MODULATORS
AR030018A1
(en)
DERIVATIVES OF BENZO (D) (1,3) OXAZIN-2-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THE USE OF THE SAME TO PREPARE MEDICATIONS AS PROGESTERONE RECEPTING MODULATORS
COMPOUNDS DERIVED FROM 3, 16-DIHIDROXI-ESTRA-1,3,5 (10) -TRIENO, EMPLOYMENT OF THE SAME AND STRUCTURAL PARTS OF THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DERIVATIVES OF BENZO (D) (1,3) OXAZIN-2-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THE USE OF THE SAME TO PREPARE MEDICATIONS AS PROGESTERONE RECEPTING MODULATORS
16alpha-substituted steroidal compound, use thereof, treatment methods for selective activation of alpha subtype estrogen receptors, and for hormone replacement therapy or contraception, and, pharmaceutical composition