AR020158A1 - INDUCTION FACTOR IMPROVER FOR CELL DIFFERENTIATION - Google Patents

INDUCTION FACTOR IMPROVER FOR CELL DIFFERENTIATION

Info

Publication number
AR020158A1
AR020158A1 ARP990104011A ARP990104011A AR020158A1 AR 020158 A1 AR020158 A1 AR 020158A1 AR P990104011 A ARP990104011 A AR P990104011A AR P990104011 A ARP990104011 A AR P990104011A AR 020158 A1 AR020158 A1 AR 020158A1
Authority
AR
Argentina
Prior art keywords
cell differentiation
induction factor
factor improver
improver
optionally substituted
Prior art date
Application number
ARP990104011A
Other languages
Spanish (es)
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AR020158A1 publication Critical patent/AR020158A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Esta invencion provee un mejorador de factor de induccion de diferenciacion celular que comprende un compuesto de formula (1), en donde el anillo A es unanillo de benceno opcionalmente sustituido; R es un átomo de hidrogeno o un grupo hidrocarburo opcionalmente sustituido; B es un grupo carboxiloopcionalmente esterificado o amidado; X es -CH(OH)- o -CO-; k es 0 o 1; y k es 0, 1 o 2; o su sal, que puede ser ventajosamente usado comoun mejorador de factor de induccion de diferenciacion celular.This invention provides a cell differentiation induction factor enhancer comprising a compound of formula (1), wherein ring A is an optionally substituted benzene ring; R is a hydrogen atom or an optionally substituted hydrocarbon group; B is an optionally esterified or amidated carboxy group; X is -CH (OH) - or -CO-; k is 0 or 1; and k is 0, 1 or 2; or its salt, which can be advantageously used as a cell differentiation induction factor improver.

ARP990104011A 1998-08-12 1999-08-11 INDUCTION FACTOR IMPROVER FOR CELL DIFFERENTIATION AR020158A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22830098 1998-08-12

Publications (1)

Publication Number Publication Date
AR020158A1 true AR020158A1 (en) 2002-04-10

Family

ID=16874304

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990104011A AR020158A1 (en) 1998-08-12 1999-08-11 INDUCTION FACTOR IMPROVER FOR CELL DIFFERENTIATION

Country Status (5)

Country Link
EP (1) EP1105140A2 (en)
AR (1) AR020158A1 (en)
AU (1) AU5196099A (en)
CA (1) CA2340165A1 (en)
WO (1) WO2000009100A2 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008517A2 (en) * 1996-08-26 1998-03-05 Takeda Chemical Industries, Ltd. Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol
ATE203020T1 (en) * 1990-05-30 2001-07-15 Takeda Chemical Industries Ltd SULFUR CONTAINING HETEROCYCLIC COMPOUNDS
TW403757B (en) * 1994-12-28 2000-09-01 Takeda Chemical Industries Ltd Optically active benzothiepin derivative, its preparation and use
WO1996025929A1 (en) * 1995-02-21 1996-08-29 Takeda Chemical Industries, Ltd. Use of helioxanthin as an enhancer of cell differentiation inducing factors
RU2188011C2 (en) * 1995-06-05 2002-08-27 Такеда Кемикал Индастриз, Лтд. Osteogenesis-activating pharmaceutical composition
AU4135397A (en) * 1996-09-06 1998-03-26 Takeda Chemical Industries Ltd. Condensed 4,5,6,7-tetrahydrobenzo{c}thiophenes as enhancer for cell differentiation induction factor action

Also Published As

Publication number Publication date
CA2340165A1 (en) 2000-02-24
AU5196099A (en) 2000-03-06
WO2000009100A2 (en) 2000-02-24
WO2000009100A3 (en) 2000-08-24
EP1105140A2 (en) 2001-06-13

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