AR017513A1 - COMBINED PHARMACEUTICAL PREPARATION CONTAINING AN EXCHANGER OF THE EXCHANGER BETWEEN SODIUM AND HYDROGEN AND COMMERCIAL CONTAINER INTENDED FOR THE TREATMENT OF CARDIOCIRCULATORY DISEASES - Google Patents
COMBINED PHARMACEUTICAL PREPARATION CONTAINING AN EXCHANGER OF THE EXCHANGER BETWEEN SODIUM AND HYDROGEN AND COMMERCIAL CONTAINER INTENDED FOR THE TREATMENT OF CARDIOCIRCULATORY DISEASESInfo
- Publication number
- AR017513A1 AR017513A1 ARP980104222A ARP980104222A AR017513A1 AR 017513 A1 AR017513 A1 AR 017513A1 AR P980104222 A ARP980104222 A AR P980104222A AR P980104222 A ARP980104222 A AR P980104222A AR 017513 A1 AR017513 A1 AR 017513A1
- Authority
- AR
- Argentina
- Prior art keywords
- exchanger
- treatment
- pharmaceutical preparation
- sodium
- hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Preparado farmacéutico, caracterizado porque contiene un inhibidor del intercambiador entre Na+ y H+ y una sustancia activa sobre el corazon y lacirculacion. En este caso, tales combinaciones de un inhibidor del NHE pueden constar de uno o varios componentes terapéuticos activos sobre lacirculacion. La combinacion de las propiedades protectoras del corazon con terapias conocidas de enfermedades cardiocirculatorias conduce por unaparte a un mejoramiento de la calidad del tratamiento y por otra parte, en numerosas combinaciones, a un refuerzo aditivo o potenciador de losefectos sobre el corazon y la circulacion de los componentes individuales de efecto, tomados a solas. Un envase comercial que comprende dichopreparado farmacéutico combinado destinado al tratamiento de enfermedades cardiocirculatorias.Pharmaceutical preparation, characterized in that it contains an inhibitor of the exchanger between Na + and H + and an active substance on the heart and circulation. In this case, such combinations of an NHE inhibitor may consist of one or more therapeutic components active on circulation. The combination of the protective properties of the heart with known therapies of cardiocirculatory diseases leads by a part to an improvement in the quality of the treatment and on the other hand, in numerous combinations, to an additive or enhancer reinforcement of the effects on the heart and the circulation of the individual components of effect, taken alone. A commercial package comprising combined pharmaceutical dichopreparate intended for the treatment of cardiocirculatory diseases.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19737224A DE19737224A1 (en) | 1997-08-27 | 1997-08-27 | Pharmaceutical preparation for cardiovascular treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
AR017513A1 true AR017513A1 (en) | 2001-09-12 |
Family
ID=7840257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980104222A AR017513A1 (en) | 1997-08-27 | 1998-08-25 | COMBINED PHARMACEUTICAL PREPARATION CONTAINING AN EXCHANGER OF THE EXCHANGER BETWEEN SODIUM AND HYDROGEN AND COMMERCIAL CONTAINER INTENDED FOR THE TREATMENT OF CARDIOCIRCULATORY DISEASES |
Country Status (23)
Country | Link |
---|---|
US (1) | US6348476B1 (en) |
EP (1) | EP0937464B1 (en) |
JP (1) | JP4436940B2 (en) |
KR (1) | KR19990023904A (en) |
CN (1) | CN1172665C (en) |
AR (1) | AR017513A1 (en) |
AU (1) | AU738598B2 (en) |
BR (1) | BR9803233A (en) |
CA (1) | CA2245776A1 (en) |
CZ (1) | CZ270998A3 (en) |
DE (1) | DE19737224A1 (en) |
HK (1) | HK1018211A1 (en) |
HR (1) | HRP980464A2 (en) |
HU (1) | HUP9801924A3 (en) |
IL (1) | IL125913A0 (en) |
NO (1) | NO320264B1 (en) |
NZ (1) | NZ331533A (en) |
PL (1) | PL195566B1 (en) |
RU (1) | RU2227751C2 (en) |
SK (1) | SK116798A3 (en) |
TR (1) | TR199801661A2 (en) |
TW (1) | TW589175B (en) |
ZA (1) | ZA987723B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19945302A1 (en) * | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenyl derivatives as NHE-3 inhibitors |
US6423705B1 (en) | 2001-01-25 | 2002-07-23 | Pfizer Inc. | Combination therapy |
IL147696A0 (en) * | 2001-01-25 | 2002-08-14 | Pfizer Prod Inc | Combination therapy |
US6844361B2 (en) | 2002-02-04 | 2005-01-18 | Aventis Pharma Deutschland Gmbh | Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor |
ATE520398T1 (en) * | 2002-02-04 | 2011-09-15 | Sanofi Aventis Deutschland | COMBINATION PREPARATION OF THE SODIUM-HYDROGEN EXCHANGE INHIBITOR CARIPORIDE WITH RAMIPRIL FOR PREVENTING OR INHIBITING HEART FAILURE |
US7375138B2 (en) * | 2002-05-18 | 2008-05-20 | Sanofi-Aventis Deutschland Gmbh | Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them |
FR2840302B1 (en) * | 2002-06-03 | 2004-07-16 | Aventis Pharma Sa | ISOINDOLONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIARY THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME |
US6878748B2 (en) | 2002-06-13 | 2005-04-12 | Aventis Pharma Deutschland Gmbh | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them |
MXPA05011840A (en) * | 2003-05-06 | 2006-01-26 | Merck Patent Gmbh | Method for crystallizing guanidinium salts. |
US7534894B2 (en) | 2003-09-25 | 2009-05-19 | Wyeth | Biphenyloxy-acids |
DE10356717A1 (en) * | 2003-12-02 | 2005-07-07 | Aventis Pharma Deutschland Gmbh | Process for the preparation of (3-oxo-2,3-dihydro-1H-isoindol-1-yl) -acetylguanidine derivatives |
US7531569B2 (en) * | 2003-12-02 | 2009-05-12 | Sanofi-Aventis Deutschland Gmbh | Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives |
AU2005301989A1 (en) * | 2004-11-05 | 2006-05-11 | King Pharmaceuticals Research & Development, Inc. | Stabilized individually coated ramipril particles, compositions and methods |
US10517839B2 (en) | 2008-06-09 | 2019-12-31 | Cornell University | Mast cell inhibition in diseases of the retina and vitreous |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
EP3960165A1 (en) * | 2020-08-25 | 2022-03-02 | Fondation EspeRare | Nhe-1 inhibitors for the treatment of coronavirus infections |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0556673B1 (en) | 1992-02-15 | 1997-09-17 | Hoechst Aktiengesellschaft | Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as medicaments containing them |
DE59305042D1 (en) * | 1992-09-22 | 1997-02-20 | Hoechst Ag | Benzoylguanidines, processes for their preparation and their use as antiarrhythmics |
DE4328869A1 (en) | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
DE4421536A1 (en) | 1994-06-20 | 1995-12-21 | Hoechst Ag | Phenyl-substituted alkenylcarboxylic acid guanidines bearing perfluoroalkyl groups, processes for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them |
DE4422685A1 (en) | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituted benzoylguanidines, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them |
DE4432106A1 (en) | 1994-09-09 | 1996-03-14 | Hoechst Ag | Heterocyclic N-oxide-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic, medicament containing them and intermediates for their preparation |
DE19741635A1 (en) * | 1997-09-22 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Biphenylsulfonylcyanamides, process for their preparation and their use as a medicament |
-
1997
- 1997-08-27 DE DE19737224A patent/DE19737224A1/en not_active Withdrawn
-
1998
- 1998-08-21 EP EP98115754A patent/EP0937464B1/en not_active Expired - Lifetime
- 1998-08-24 IL IL12591398A patent/IL125913A0/en not_active IP Right Cessation
- 1998-08-25 SK SK1167-98A patent/SK116798A3/en unknown
- 1998-08-25 TR TR1998/01661A patent/TR199801661A2/en unknown
- 1998-08-25 BR BR9803233-0A patent/BR9803233A/en not_active Application Discontinuation
- 1998-08-25 NZ NZ331533A patent/NZ331533A/en unknown
- 1998-08-25 CZ CZ982709A patent/CZ270998A3/en unknown
- 1998-08-25 AR ARP980104222A patent/AR017513A1/en unknown
- 1998-08-25 CA CA002245776A patent/CA2245776A1/en not_active Abandoned
- 1998-08-26 ZA ZA987723A patent/ZA987723B/en unknown
- 1998-08-26 HR HR19737224.4A patent/HRP980464A2/en not_active Application Discontinuation
- 1998-08-26 CN CNB981187013A patent/CN1172665C/en not_active Expired - Fee Related
- 1998-08-26 NO NO19983926A patent/NO320264B1/en unknown
- 1998-08-26 JP JP24020398A patent/JP4436940B2/en not_active Expired - Fee Related
- 1998-08-26 AU AU81908/98A patent/AU738598B2/en not_active Ceased
- 1998-08-26 HU HU9801924A patent/HUP9801924A3/en unknown
- 1998-08-26 RU RU98116126/15A patent/RU2227751C2/en not_active IP Right Cessation
- 1998-08-27 PL PL328251A patent/PL195566B1/en unknown
- 1998-08-27 KR KR1019980034758A patent/KR19990023904A/en not_active Application Discontinuation
- 1998-10-07 TW TW087113939A patent/TW589175B/en not_active IP Right Cessation
-
1999
- 1999-07-28 HK HK99103247A patent/HK1018211A1/en not_active IP Right Cessation
-
2000
- 2000-07-05 US US09/610,425 patent/US6348476B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1209316A (en) | 1999-03-03 |
IL125913A0 (en) | 1999-04-11 |
NO983926L (en) | 1999-03-01 |
PL195566B1 (en) | 2007-10-31 |
EP0937464B1 (en) | 2012-07-11 |
SK116798A3 (en) | 1999-03-12 |
BR9803233A (en) | 2000-05-02 |
JPH11139990A (en) | 1999-05-25 |
NZ331533A (en) | 2000-04-28 |
PL328251A1 (en) | 1999-03-01 |
HUP9801924A2 (en) | 2000-02-28 |
ZA987723B (en) | 1999-03-01 |
NO983926D0 (en) | 1998-08-26 |
TW589175B (en) | 2004-06-01 |
US6348476B1 (en) | 2002-02-19 |
EP0937464A3 (en) | 2003-09-24 |
NO320264B1 (en) | 2005-11-14 |
CZ270998A3 (en) | 1999-03-17 |
EP0937464A2 (en) | 1999-08-25 |
DE19737224A1 (en) | 1999-03-18 |
HUP9801924A3 (en) | 2004-11-29 |
KR19990023904A (en) | 1999-03-25 |
CN1172665C (en) | 2004-10-27 |
HRP980464A2 (en) | 1999-06-30 |
CA2245776A1 (en) | 1999-02-27 |
RU2227751C2 (en) | 2004-04-27 |
HK1018211A1 (en) | 1999-12-17 |
TR199801661A2 (en) | 1999-03-22 |
AU8190898A (en) | 1999-03-11 |
AU738598B2 (en) | 2001-09-20 |
HU9801924D0 (en) | 1998-10-28 |
JP4436940B2 (en) | 2010-03-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |