AR017253A1 - A PROCEDURE TO PREPARE TRI-ARILALQUILALQUENOS AND INTERMEDIARIES - Google Patents
A PROCEDURE TO PREPARE TRI-ARILALQUILALQUENOS AND INTERMEDIARIESInfo
- Publication number
- AR017253A1 AR017253A1 ARP980103299A ARP980103299A AR017253A1 AR 017253 A1 AR017253 A1 AR 017253A1 AR P980103299 A ARP980103299 A AR P980103299A AR P980103299 A ARP980103299 A AR P980103299A AR 017253 A1 AR017253 A1 AR 017253A1
- Authority
- AR
- Argentina
- Prior art keywords
- arilalquilalquenos
- intermediaries
- procedure
- prepare tri
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/48—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describe un procedimiento para preparar tri-arilalquilalquenos de la formula (I) en la cual Ar1, Ar2 y Ar3 pueden ser grupos aromáticos iguales odiferentes, y R1 es alquilo o alquilo sustituido, que se procede a calentar en un disolvente de un compuesto de la formula (II) en la cual -COR2 es un derivadode acilo. Se describen también compuestos intermediarios nuevos.A process for preparing tri-arylalkylalkenes of the formula (I) in which Ar1, Ar2 and Ar3 can be odifferent equal aromatic groups is described, and R1 is alkyl or substituted alkyl, which is heated in a solvent of a compound of Formula (II) in which -COR2 is an acyl derivative. New intermediary compounds are also described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9714310.1A GB9714310D0 (en) | 1997-07-07 | 1997-07-07 | Process |
Publications (1)
Publication Number | Publication Date |
---|---|
AR017253A1 true AR017253A1 (en) | 2001-09-05 |
Family
ID=10815497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980103299A AR017253A1 (en) | 1997-07-07 | 1998-07-07 | A PROCEDURE TO PREPARE TRI-ARILALQUILALQUENOS AND INTERMEDIARIES |
Country Status (6)
Country | Link |
---|---|
AR (1) | AR017253A1 (en) |
AU (1) | AU8232098A (en) |
CO (1) | CO4940497A1 (en) |
GB (1) | GB9714310D0 (en) |
WO (1) | WO1999002509A1 (en) |
ZA (1) | ZA985917B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103992234B (en) * | 2014-06-11 | 2016-05-18 | 扬子江药业集团江苏海慈生物药业有限公司 | A kind of preparation method of tamoxifen citrate E isomers |
CN114133334A (en) * | 2021-11-09 | 2022-03-04 | 北京京丰制药(山东)有限公司 | Industrial preparation process of tamoxifen citrate |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU171269B (en) * | 1976-02-05 | 1977-12-28 | Gyogyszerkutato Intezet | Process for preparing new triphenyl-alkene derivatives |
DE3046719C2 (en) * | 1980-12-11 | 1983-02-17 | Klinge Pharma GmbH, 8000 München | 1,1,2-Triphenyl-but-1-ene derivatives, processes for their preparation and pharmaceuticals |
GB2196003A (en) * | 1986-09-11 | 1988-04-20 | Nat Res Dev | Iodo-and bromo-tamoxifen derivatives |
WO1996014283A1 (en) * | 1994-11-02 | 1996-05-17 | EGIS Gyógyszergyár Rt. | Process and intermediates for preparing triphenyltrifluoropropanes and -propenes |
-
1997
- 1997-07-07 GB GBGB9714310.1A patent/GB9714310D0/en active Pending
-
1998
- 1998-07-06 ZA ZA985917A patent/ZA985917B/en unknown
- 1998-07-07 CO CO98038357A patent/CO4940497A1/en unknown
- 1998-07-07 WO PCT/GB1998/001990 patent/WO1999002509A1/en active Application Filing
- 1998-07-07 AU AU82320/98A patent/AU8232098A/en not_active Abandoned
- 1998-07-07 AR ARP980103299A patent/AR017253A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1999002509A1 (en) | 1999-01-21 |
AU8232098A (en) | 1999-02-08 |
ZA985917B (en) | 1999-04-01 |
GB9714310D0 (en) | 1997-09-10 |
CO4940497A1 (en) | 2000-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |