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Application filed by Univ Hawaii, Univ Wayne StatefiledCriticalUniv Hawaii
Priority to ARP970104265priorityCriticalpatent/AR012019A1/en
Publication of AR012019A1publicationCriticalpatent/AR012019A1/en
La invencion proporciona nuevos compuestos de criptoficina, los cuales pueden ser utiles al interrumpir el sistema de la microtubulina, comoagente antineoplásico y para el tratamiento del cáncer. La invencion provee asimismo una formulacionque comprende dichos compuestos novedosos decriptoficina, de formula (I), donde Ar, X, Y, R1, a R11, R13, R14 y R30, tienen los valores indicados en la descripcion.The invention provides new cryptophycin compounds, which may be useful in disrupting the microtubulin system, as an antineoplastic agent and for the treatment of cancer. The invention also provides a formulation comprising said novel decriptophycin compounds, of formula (I), where Ar, X, Y, R1, R11, R13, R14 and R30 have the values indicated in the description.
ARP9701042651997-09-171997-09-17
CRYPTOFICINE COMPOUND AND ITS USE TO PREPARE A MEDICATION
AR012019A1
(en)
SOLID PHARMACEUTICAL COMPOSITIONS, PROCESS FOR PREPARATION, KIT FOR THE TREATMENT OF OBESITY AND USE OF SUCH COMPOSITIONS IN THE DEVELOPMENT OF MEDICINES
ANALOG COMPOUNDS OF (1R, CIS) -4- (6-AMINO-9H-PURIN-9-IL) -2-CYCLOPENTENE-1-METHANOL, PROCESS FOR PREPARATION, USE IN THE TREATMENT OF VIRAL INFECTIONS, AND PACKING THAT CONTAINS THEM