AR010670A1 - THROMBOLITIC AGENT - Google Patents
THROMBOLITIC AGENTInfo
- Publication number
- AR010670A1 AR010670A1 ARP970105658A AR010670A1 AR 010670 A1 AR010670 A1 AR 010670A1 AR P970105658 A ARP970105658 A AR P970105658A AR 010670 A1 AR010670 A1 AR 010670A1
- Authority
- AR
- Argentina
- Prior art keywords
- conjugates
- methods
- provides
- thrombolytic agents
- vivo
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Proporciona agentes trombolíticos y métodos para elaborar y utilizar agentes trombolíticos. Específicamente, proporciona agentes trombolíticos queconstan de una proteinasa unida en forma covalente a un compuesto buscardor de blancos que de manera específica, se une al sitio de coágulos sanguíneos ytrombos in vivo. También proporciona conjungados de una proteinasa trombolítica y cuando menos, dos compuestos buscadores de blancos. También se proporcionanlos métodos para producir dichos conjugados y los métodos de empleo de dichos conjugados para la eliminacion de trombos in vivo para aliviar, de ese modo, elestado patologico causado.Provides thrombolytic agents and methods for making and using thrombolytic agents. Specifically, it provides thrombolytic agents that consist of a proteinase covalently bound to a target-seeking compound that specifically binds to the site of blood clots and thrombi in vivo. It also provides conjugates of a thrombolytic proteinase and at least two target-seeking compounds. Also provided are the methods of producing such conjugates and the methods of employing such conjugates for thrombus removal in vivo to thereby alleviate the pathological condition caused.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/753,781 US5951981A (en) | 1996-12-02 | 1996-12-02 | Thrombolytic agents with antithrombotic activity |
| US75378197A | 1997-12-02 | 1997-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR010670A1 true AR010670A1 (en) | 2000-06-28 |
Family
ID=45724774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105658 AR010670A1 (en) | 1996-12-02 | 1997-12-02 | THROMBOLITIC AGENT |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR010670A1 (en) |
-
1997
- 1997-12-02 AR ARP970105658 patent/AR010670A1/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |