AR010336A1 - USE OF 17 ALPHA-DIHYDROEKYLENINE OR A PHARMACEUTICALLY ACCEPTABLE SALT OF 17-ALPHA-DIHYDROEKYLENINE-3-SULPHATE FOR THE MANUFACTURE OF A USEFUL MEDICINAL PRODUCT TO INHIBIT OR TREAT PATHOLOGIES INDUCED BY FREE RADICALS AND A COMPOSITION. - Google Patents

USE OF 17 ALPHA-DIHYDROEKYLENINE OR A PHARMACEUTICALLY ACCEPTABLE SALT OF 17-ALPHA-DIHYDROEKYLENINE-3-SULPHATE FOR THE MANUFACTURE OF A USEFUL MEDICINAL PRODUCT TO INHIBIT OR TREAT PATHOLOGIES INDUCED BY FREE RADICALS AND A COMPOSITION.

Info

Publication number
AR010336A1
AR010336A1 ARP970105739A ARP970105739A AR010336A1 AR 010336 A1 AR010336 A1 AR 010336A1 AR P970105739 A ARP970105739 A AR P970105739A AR P970105739 A ARP970105739 A AR P970105739A AR 010336 A1 AR010336 A1 AR 010336A1
Authority
AR
Argentina
Prior art keywords
alpha
dihydroekylenine
pharmaceutically acceptable
inhibit
manufacture
Prior art date
Application number
ARP970105739A
Other languages
Spanish (es)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR010336A1 publication Critical patent/AR010336A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Abstract

Uso de 17alfa dihidroequilenina o una sal farmacéuticamente aceptable del éster 17alfa dihidroequilenina-3-sulfato para la manufactura de un medicamentoutil para inhibir o tratar patologías inducidas por los radicales libres libres , caracterizadoporque comprende una cantidad antioxidante de 17 alfa--dihidroequilenina o una sal farmacéuticamente aceptable de éster de 17alfa- -dihidroequilenina-3-sulfato destinado, a un mamifero en necesidad del mismo, yun vehículo farmacéuticamente aceptable, composicion farmacéutica que los comprende.Use of 17alpha dihydroekylene or a pharmaceutically acceptable salt of 17alpha dihydroekylene-3-sulfate ester for the manufacture of a drugoutil to inhibit or treat pathologies induced by free radicals, characterized in that it comprises an antioxidant amount of 17 alpha-dihydroekylene or a pharmaceutically Acceptable 17alpha- -dihydroekylene-3-sulfate ester intended for a mammal in need thereof, and a pharmaceutically acceptable carrier, pharmaceutical composition comprising them.

ARP970105739A 1996-12-09 1997-12-05 USE OF 17 ALPHA-DIHYDROEKYLENINE OR A PHARMACEUTICALLY ACCEPTABLE SALT OF 17-ALPHA-DIHYDROEKYLENINE-3-SULPHATE FOR THE MANUFACTURE OF A USEFUL MEDICINAL PRODUCT TO INHIBIT OR TREAT PATHOLOGIES INDUCED BY FREE RADICALS AND A COMPOSITION. AR010336A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76263496A 1996-12-09 1996-12-09

Publications (1)

Publication Number Publication Date
AR010336A1 true AR010336A1 (en) 2000-06-07

Family

ID=25065657

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970105739A AR010336A1 (en) 1996-12-09 1997-12-05 USE OF 17 ALPHA-DIHYDROEKYLENINE OR A PHARMACEUTICALLY ACCEPTABLE SALT OF 17-ALPHA-DIHYDROEKYLENINE-3-SULPHATE FOR THE MANUFACTURE OF A USEFUL MEDICINAL PRODUCT TO INHIBIT OR TREAT PATHOLOGIES INDUCED BY FREE RADICALS AND A COMPOSITION.

Country Status (13)

Country Link
EP (1) EP0946182A1 (en)
JP (1) JP2001506629A (en)
KR (1) KR20000069346A (en)
CN (1) CN1239890A (en)
AR (1) AR010336A1 (en)
AU (1) AU743519B2 (en)
BR (1) BR9714382A (en)
CA (1) CA2272089A1 (en)
HU (1) HUP0000570A3 (en)
IL (1) IL130069A0 (en)
NZ (1) NZ336341A (en)
WO (1) WO1998025627A1 (en)
ZA (1) ZA9711053B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271221B1 (en) * 1996-12-10 2001-08-07 American Home Products Corporation Use of equilenin as an antioxidant
DE10154221A1 (en) * 2001-11-07 2003-05-15 Max Delbrueck Centrum Agent for the treatment of lesions of the nervous system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4338314C1 (en) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmaceutical preparations for the prophylaxis and therapy of radical-mediated cell damage

Also Published As

Publication number Publication date
IL130069A0 (en) 2000-02-29
CA2272089A1 (en) 1998-06-18
KR20000069346A (en) 2000-11-25
HUP0000570A3 (en) 2000-12-28
BR9714382A (en) 2000-05-16
NZ336341A (en) 2002-02-01
AU743519B2 (en) 2002-01-31
AU5464498A (en) 1998-07-03
ZA9711053B (en) 1999-06-09
CN1239890A (en) 1999-12-29
EP0946182A1 (en) 1999-10-06
HUP0000570A2 (en) 2000-10-28
JP2001506629A (en) 2001-05-22
WO1998025627A1 (en) 1998-06-18

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